齐宪荣 - 北京大学

个人简介

教育及工作经历 2007.8至今北京大学药学院教授 1998.7-2007.7 北京大学药学院副教授 1993.6-1997.6 日本星药科大学客座研究员 1993.7-1998.7 北京医科大学药学院讲师 1987.8-1993.7 北京医科大学药学院助教 1993.6-1997.3 星药科大学（日本）药学博士学位 1982.9-1987.7 北京医科大学药学院理学学士学位荣誉及奖励 2016年北京大学药学院教学优秀奖 2016年北京大学医学部仲外奖教金 2015年北京大学医学部发明专利奖 2014年中国制剂大会优秀论文一等奖（学生王爱婷） 2014年北京大学优秀博士学位论文指导教师（博士生仰浈臻） 2014年医学部大学生创新实验项目一等奖（学生庞宁） 2014年北京大学优秀共产党员 2013年北京大学优秀博士学位论文指导教师（博士生高玮） 2012年北京大学医学部SCI论文引用奖 2012年教育部“高等学校科学技术奖”-自然科学一等奖（5/10 证书号2012-002） 2011年香港大学荣誉教授（2011.1.1-2013.12.31） 2010年北京大学优秀共产党员 2009年高等学校自然科学一等奖（5/9） 2008年北京大学药学院优秀共产党 2008年香港大学荣誉教授（2008.1.1-2010.12.31） 2007年中国中西医结合学会科学技术一等奖（5/17 证书号20078601A） 2007年药学学报优秀论文奖 2003年教育部科技进步二等奖（3/10 证书号2003-049） 2002年中国药剂学会优秀论文一等奖 2001年北京市科技进步三等奖（1/4 证书号2001-药-3-007-1） 2000年中国高校科技进步二等奖（2/3 证书号2000-64） 1999年中国药学会优秀论文二等奖 1998年第四届北医大国际交流论文三等奖 1996年北京医科大学教学优秀奖 1996年永井国际基金会出版奖 1995年国家教委科技进步二等奖（第7完成人证书号95-189）

研究领域

1.药物递送系统的构筑、靶向化设计与评价 2.纳米技术与生物技术

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. 2017 Yang, Zhen-zhen; Gao, Wei; Liu, Yu-jie; Pang, Ning; Qi, Xian-rong*. Delivering siRNA and Chemotherapeutic Molecules Across BBB and BTB for Intracranial Glioblastoma Therapy. Molecular Pharmaceutics (2017), 14(4), 1012-1022. 2. 2017 Shi, Nian-Qiu; Qi, Xian-Rong*. Taming the Wildness of "Trojan-Horse" Peptides by Charge-Guided Masking and Protease-Triggered Demasking for the Controlled Delivery of Antitumor Agents. ACS Applied Materials & Interfaces (2017), 9(12), 10519-10529. 3. 2017 De-Sheng Liang, Wen-Jie Zhang, Ai-Ting Wang, Hai-Tao Su, Hai-Jun Zhong, Xian-Rong Qi*. Treating metastatic triple negative breast cancer with CD44 neuropilin dual molecular targets of multifunctional nanoparticles. Biomaterials 137 (2017) 23-36. 4. 2017 Yu-Jie Liu, Ying-Cong Ma, Wen-Jie Zhang, Zhen-Zhen Yang, De-Sheng Liang, Zhi-Fu Wu, Xian-Rong Qi*. Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation. Oncotarget. Oncotarget. 2017; 8:42495-42509. 5. 2017 Yingcong Ma, Yujie Liu, Aning Sun, Yitian Du, Min Ye, Xiaoping Pu, Xianrong Qi*. Intestinal absorption and neuroprotective effects of kaempferol-3-O-rutinoside. RSC Adv., 2017, 7, 31408–31416. 6. 2017 Xin Li, Ning Pang, Ji Li, Xianrong Qi*. Characterization of amphiphilic dendrimer modified PEG-PLA nanoparticles prepared by a double emulsion-solvent evaporation method. J. Chin. Pharm. Sci. 2017, 26 (7), 521–527. 7. 2017 Yi Zhang, Ying Zhan, Ning Pang, Yujie Liu, Shixuan Cheng, Ji Li, Yitian Du, Xianrong Qi*. Preparation, characterization and pharmacokinetics of 10-hydroxycamptothecin nanosuspension. J. Chin. Pharm. Sci. 2017, 26 (8), 574–581. 8. 2016 Hai-Tao Su, Xin Li, De-Sheng Liang, Xian-Rong Qi*. Synthetic low-density lipoprotein (sLDL) selectively delivery paclitaxel to tumor with low systemic toxicity. Oncotarget, 2016，7（32）51535-52。 9. 2015 D.S. Liang, H.T. Su, Y.J. Liu, A.T. Wang, X.R. Qi*. Tumor-specific penetrating peptides-functionalized hyaluronic acid-d-α-tocopheryl succinate based nanoparticles for multi-task delivery to invasive cancers. Biomaterials 2015, 71, 11-23. 10. 2015 W. Gao , T. Meng , N. Shi , H. Zhuang , Z. Yang , X.R. Qi*. Targeting and microenvironment responsive lipid nanocarrier for the enhancement of Targeting and Microenvironment-Responsive Lipid Nanocarrier for the Enhancement of Tumor Cell Recognition and Therapeutic Efficiency. Adv. Healthc. Mater. 2015, 4, 748 –759. 11. 2015 A. Wang, D. Liang, Y. Liu, X.R. Qi*. Roles of ligand and TPGS of micelles in regulating internalization, penetration and accumulation against sensitive or resistant tumor and therapy for multidrug resistant tumors. Biomaterials 2015, 53, 160-172. 12. 2015 D. Dong, W. Gao, Y. Liu, X.R. Qi*. Therapeutic potential of targeted multifunctional nanocomplex co-delivery of siRNA and low-dose doxorubicin in breast cancer. Cancer Letters 2015, 359, 178 –186. 13. 2015 L. Sun, Y.J. Liu, Z.Z. Yang, X.R. Qi*. Tumor specific delivery with redox-1 triggered mesoporous silica nanoparticles inducing neovascularization suppression and vascular normalization. RSC Advances, 2015, 5, 55566-55578. 14. 2015 D.S. Liang, H.T. Su, Y.J Liu, A.T. Wang, X.R. Qi*. Enhance Cancer Cell Recognition and Overcome Drug Resistance Using Hyaluronic Acid and α-Tocopheryl Succinate Based Multifunctional Nanoparticles. Mol. Pharmaceutics, 2015, 12 (6), 2189 –2202. 15. 2014 Z.Z. Yang, J.Q. Li, Z.Z. Wang, D.W. Dong, X.R. Qi*. Tumor-targeting dual peptides-modified cationic liposomes for delivery of siRNA and docetaxel to gliomas. Biomaterials 2014, 35, 5226-5239. 16. 2014 Z. Yang, B. Xiang, D. Dong, Z. Wang, J. Li, X.R. Qi*. Dual receptor-specific peptides modified liposomes as VEGF siRNA vector for tumor-targeting therapy. Current Gene Therapy. 2014, 4,289-299. 17. 2014 N.Q. Shi*, X.R. Qi*, B Xiang, Y Zhang. A survey on“Trojan Horse”peptides Opportunities, issues and controlled entry to“Troy”. J. Control. Release 2014, 194, 53 –70. 18. 2014 K. Wu, Z.Z. Wang, D. Liu, X.R. Qi*. Pharmacokinetics, brain distribution, release and blood–brain barrier transport of Shunaoxin pills. J. Ethnopharmacol. 2014, 151, 1133-1140. 19. 2013 W. Gao, B. Xiang, T. Meng, F. Liu, X.R. Qi *. Chemotherapeutic drug delivery to cancer cells using a combination of folate targeting and tumor microenvironment-sensitive polypeptides. Biomaterials. 2013, 34: 4137-4149. 20. 2013 D. Dong, B. Xiang,W. Gao, Z. Yang, J. Li, X.R. Qi *. pH-responsive complexes using prefunctionalized polymers for synchronous delivery of doxorubicin and siRNA to cancer cells. Biomaterials. 2013, 34: 4849-4859. 21. 2013 B Xiang, D Dong, N Shi, W Gao, Z Yang, Y Cui, D Cao, XR Qi*. PSA-responsive and PSMA-mediated multifunctional liposomes for targeted therapy of prostate cancer. Biomaterials. 2013, 34: 6976-6991. 22. 2013 D Dong, S Tong, XR Qi*. Comparative studies of polyethylenimine-doxorubicin conjugates with pH-sensitive and pH-insensitive linkers. J. Biomed. Mater. Res. 2013, 101A, 1336-1344. 23. 2013 ZZ Yang, YQ Zhang, ZZ Wang, K Wu, JN Lou, XR Qi*. Enhanced brain distribution and pharmacodynamics of rivastigmine by liposomes following intranasal administration. Int. J. Pharm. 2013, 452, 344 –354. 24. 2012 ZZ Yang, ZZ Wang, K Wu, XR Qi*. Tissue Distribution and Pharmacodynamics of Rivastigmine after Intranasal and Intravenous Administration in Rats. Current Alzheimer Res. 2012, 9(3), 315-325. 25. 2012 SW Tong, B Xiang, DW Dong, XR Qi*. Enhanced antitumor efficacy and decreased toxicity by self-associated docetaxel in phospholipid-based micelles. Int. J. Pharm.2012, 434, 413 –419. 26. 2012 NQ Shi, W Gao, B Xiang, XR Qi*. Enhancing cellular uptake of activable cell-penetrating peptide–doxorubicin conjugate by enzymatic cleavage. Int. J. Nanomed.2012, 7, 1613 –1621. 27. ZX Lv, LT Liu, XR Qi*. Development of small interfering RNA delivery system using PEI-PEG-APRPG polymer for antiangiogenic vascular endothelial growth factor tumor-targeted therapy. Int. J. Nanomed. 2011, 6, 1661-1673. 28. 2011 DX Ma, NQ Shi, XR Qi*. Distinct transduction modes of arginine-rich cell-penetrating peptides for cargo delivery into tumor cells. Int. J. Pharm. 2011, 419 （1-2 ）, 200-208. 29. 2011 W zhao, S Zhuang, XR Qi*. Comparative study of the in vitro and in vivo characteristics of cationic and neutral liposomes. Int. J. Nanomed. 2011, 6, 3087-3098.