张玉 - 华中科技大学

个人简介

现任协和医院党委书记、协和医院（西院）党委书记、医院管理研究所副所长、药学教研室主任、临床药学研究室主任；中华医学会临床药学分会第三届委员会副主委；中国药学会第六届医院药学专业委员会副主委；湖北省医学会临床药学分会第一届委员会主任委员；湖北省药学会第十二届理事会医院药学专业委员会主任委员；《中国医院药学杂志》主编；《中国药师》副主编；《中国现代应用药学》副主编。1991年同济医科大学药学院药学本科毕业，2002年获药学硕士学位，2012年获药理学博士学位。

研究领域

药物制剂及其生物效应；新药开发及其研制；植物多糖活性物质及其作用机制；植物多糖肝靶向及肝靶向载体可行性研究。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. A sensitive and rapid radiolabelling method for the in vivo pharmacokinetic study of lentinan. Food Funct., 2018, 9, 3114-3125.（本期封面文章） 2. Dendrobium officinale polysaccharide attenuates type 2 diabetes mellitus via the regulation of PI3K/Akt-mediated glycogen synthesis and glucose metabolism. Journal of Functional Foods. January 2018, Pages 261-271 3. Pharmacokinetics, biodistribution and receptor mediated endocytosis of a natural Angelica sinensis polysaccharide. Artificial Cells, Nanomedicine, and Biotechnology. 2018 Jan 1:1-10. 4. Investigation of the transport and absorption of Angelica sinensis polysaccharide through gastrointestinal tract both in vitro and in vivo. Drug Delivery. 2017 Nov;24(1):1360-1371. 5.Acidic Polysaccharide from Angelica sinensis Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-κB Activation, Oxidative Medicine and Cellular Longevit, Volume 2017,13 pages 6. Protective effects of Angelica sinensis polysaccharide against hyperglycemia and liver injury in multiple low-dose. Food & Function. 2016, 7, 4889-4897 7. Filicinic acid based meroterpenoids with anti-Epstein–Barr virus activities from Hypericum japonicum, Org. Lett. 2016, 18:2272−2275 8. (±)-Japonones A and B, two pairs of new enantiomers with anti-KSHV activities from Hypericum japonicum, Sci. Rep. 2016, 6, 27588. DOI: 10.1038/srep27588 9. (±)-Japonicols A–D, acylphloroglucinol-based meroterpenoid enantiomers with anti-KSHV activities from Hypericum japonicum, J. Nat. Prod. 2016, 79, 1322−1328 10. A new megastigmane sesquiterpenoid from Zanthoxylum schinifolium Sieb. et Zucc., Molecules 2016, 21, 383. DOI:10.3390/molecules21030383. 11. Two new bioactive α-pyrones from Hypericum japonicum, Molecules 2016, 21, 515. DOI:10.3390/molecules21040515 12. Chronic administration of Angelica sinensis polysaccharide effectively improves fatty liver and glucose homeostasis in high-fat diet-fed mice, Sci. Rep. 2016,6:26229 13. Polysaccharide from Lentinus edodes combined with oxaliplatin possesses the synergy and attenuation effect in hepatocellular carcinoma, cancer letters. 2016,377:117-125 14. Structural characterization and in vitro antitumor activity of an acidic polysaccharide from Angelica sinensis (Oliv.) Diels. Carbohydrate Polymers. 2016 15. The effects of polysaccharides from the root of Angelica sinensis on tumor growth and iron metabolism in H22-bearing mice. Food & Function. 2016,7:1033-1039 16. Angelica sinensis polysaccharide attenuates concanavalin A-induced liver injury in mice. International Immunopharmacology. 2016,31:140-148 17. Induction of apoptosis in S180 tumour bearing mice by polysaccharide from Lentinus edodes via mitochondria apoptotic pathway. Journal of functional foods. 2015 ,15:151-159. 18. Angelica sinensis polysaccharide regulates glucose and lipid metabolism disorder in prediabetic and streptozotocin-induced diabetic mice through the elevation of glycogen levels and reduction of inflammatory factors. Food & Function. 2015,6:902-909 19. The action of JAK, SMAD and ERK signal pathways on hepcidin suppression by polysaccharides from Angelica sinensis in rats with iron deﬁciency anemia. Food & Function,2014,5:1381-1388. 20. Structural differences and conformational characterization of five bioactive polysaccharides from Lentinus Edodes. Food Research International, 2014,62:223-232.