个人简介
教育经历 09/2012 – 06/2016自然科学博士 德国多特蒙德工业大学(马普煤炭研究所) 09/2009 – 03/2012理学硕士 华中科技大学 化学与化工学院 09/2005 – 06/2009理学本科 华中科技大学 化学与化工学院 工作经历 11/2018-至今 副教授,华中科技大学同济医学院药学院 09/2016-10/2018 高级研究员 药明康德新药开发有限公司 国内新药服务部
研究领域
主要研究兴趣为有机合成方法学和对具有抗菌和抗肿瘤活性天然产物的仿生合成。
近期论文
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1 L. Gu, Y. Zheng, E. Haldón, R. Goddard, E. Bill, W. Thiel, M. Alcarazo,α-Radical Phosphines: Synthesis, Structure and ReactivityAngew. Chem. Int. Ed.2017,56, 8790.(IF: 11.9) 2 L.Gu, L.M. Wolf, A.Zieliński, W.Thiel, M.Alcarazo,αDicationic Chelating Phosphines: Synthesis and Application to the Hydroarylation of DienesJ. Am. Chem. Soc.2017,139, 4948.(IF: 13.8) 3 L. Gu,L. M. Wolf, W. Thiel, C. W. Lehmann, M. AlcarazoReductive Elimination of C6F5-C6F5from Pd(II) Complexes: Influence of αDicationic Chelating PhosphinesOrganometallics,2018,37, 665.(IF: 3.8) 4 L. Gu, G. Gopakumar, P. Gualco, W. Thiel and M. AlcarazoBis- and Tris(pyrazolyl)borate/Methane-Stabilized PIII-Centered CationsChem. Eur. J.2014,20, 8575-8578.(IF: 5.3) 5 L. Gu, Y. Zhou, J. Zhang, Y. Gong* A highly chemo- and enantioselective nitroaldol reaction of haloenals: preparation of chiral functionalized allylic alcoholsTetrahedron: Asymmetry2012,23, 124–129.(IF: 2.1) 6 J. Carreras, G. Gopakumar,L. Gu, A. Gimeno, J. Petuškova, W. Thiel, and M. Alcarazo Polycationic Ligands in Gold Catalysis: Synthesis and Applications of Extremely π-Acidic CatalystsJ. Am. Chem. Soc. 2013,135, 18815.(IF: 13.8) 7 E. H. Haldon, A. Kozma, H. Tinnermann,L. Gu, R. Goddard, M. Alcarazo*Synthesis and Reactivity of α-Cationic Phosphines: The Effect of Imidazolinium and Amidinium SubstituentsDalton Trans., 2016,45, 1872-1876(IF: 4.0) 8 J. Zhang, L. Liu, J. Duan,L. Gu, B. Chen T. Sun Y. Gong Stereoselective One‐Pot Sequential Dehydrochlorination/trans‐Hydrofluorination Reaction ofβ‐Chloro‐α,β‐unsaturated Aldehydes or Ketones: Facile Access to (Z)‐β‐Fluoro‐β‐arylenals/β‐Fluoro‐β‐arylenonesAdv. Synth. Catal. 2017,359, 4348.(IF: 5.6) 9 M. Wei, Y. Zhou,L. Gu, F. Luo*, F. Zhang*Asymmetric organocatalytic Michael-Hemiacetalization reaction: access to chiral spirocis-δ-lactones by in situ oxidation of spiroδ-lactols.Tetrahedron Lett.,2013, 54,2546-2548.(IF: 2.2) 10 J. Zhang,L. Gu, Y. Gong*Direct Vinylogous Aldol Reaction Triggered by Tetrabutylammonium Fluoride: A Highly Regioselective and Diastereoselective Addition of Cyclic β-Haloenals to Aromatic AldehydesSynlett2012, 23,468–472.(IF: 2.1)