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个人简介

教育经历: 2001.9-2004.7: 华中科技大学同济医学院药学院,获得药理学博士学位。 1996.9-1999.7: 同济医科大学药学院,获药物化学专业硕士学位。 1985.9-1989.7: 中国药科大学中药系,获理学学士学位。 工作经历: 2014.11-今: 华中科技大学同济药学院教授,硕士、博士生导师,中药与天然药物学系主任。 2011.3-2014.11: 华中科技大学同济药学院教授,硕士、博士生导师,天然药物化学与中药学系副主任;天然药物化学课程群负责人。 2009.11-2011.2: 华中科技大学同济药学院教授,硕士、博士生导师。 2002.7-2009.10: 华中科技大学同济药学院副教授,硕士生导师。 1997.1-2002.6: 华中科技大学同济医学院药学院讲师。 1992.12-1997.12: 同济医科大学药学院助教。 海外经历: 2014.1-2014.6: 德国马尔堡大学,访问学者。 2007.7-10; 2008.7-10: 德国杜塞尔多夫大学,访问学者。 2005.9-2006.9: 德国图宾根大学及杜塞尔多夫大学,访问学者。

研究领域

主要从事天然药物活性成分的提取分离、结构鉴定、活性测试和生物合成工作。致力于核桃属、五味子属、蟹甲草属、石蒜属、贝母属等多种植物及其内生真菌的化学成分和生物活性研究;并曾对曲霉属真菌中吲哚类生物碱的异戊烯基转移酶相关生物合成基因进行过研究。

近期论文

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Ming Zhou, Jia Zhou, Junjun Liu, Jing-Jing Liang, Xiao-Gang Peng, Fang-Fang Duan, and Han-Li Ruan*. Parasubindoles A-G, Seven Eremophilanyl Indoles from the Whole Plant of Parasenecio albus. The Journal of Organic Chemistry, 2018, Just Accepted Manuscript, DOI: 10.1021/acs.joc.8b02089, Publication Date (Web): September 10, 2018 * Jian Song, Ming Zhou, Jia Zhou, Jing-Jing Liang, Xiao-Gang Peng, Junjun Liu, and Han-Li Ruan*. Schincalactones A and B, Two 5/5/6/11/3 Fused Schinortriterpenoids with a 13-Membered Carbon Ring System from Schisandra incarnate. Organic Letters, 2018, 20 (8), 2499-2502 * Ye Liu, Heng-Yi Yu, Hong-Zhe Xu, Jun-Jun Liu, Xiang-Gao Meng, Ming Zhou, and Han-Li Ruan*. Alkaloids with Immunosuppressive Activity from the Bark of Pausinystalia yohimbe. Journal of Natural Products, 2018, 81 (8), 1841–1849 * Jingjing Liang, Xiaogang Peng, Jia Zhou, Ming Zhou, Hanli Ruan* Diarylheptanoids from the Fresh Pericarps of Juglans sigillata, Chemistry of Natural Compounds, 2018, accepted * Wenming Wu & Hanli Ruan* Triterpenoids and lignans from the stems of Schisandra glaucescens Natural Product Research, 2018 Mar 12:1-7 * Jingjing Liang, Xiaogang Peng, Jia Zhou, Ming Zhou & Hanli Ruan* Diarylheptanoids from the fresh pericarps of Juglans sigillata, Natural Product Research, 2017 Dec 28:1-7 * Jian Song, Ye Liu, Ming Zhou, Hui Cao, Xiao-Gang Peng, Jing-Jing Liang, Xiao-Ya Zhao, Ming Xiang, Han-Li Ruan*. Spiroschincarins A–E: Five Spirocyclic Nortriterpenoids from the Fruit of Schisandra incarnata. Organic Letters, 2017, 19 (5), 1196–1199 * Ye Liu, Heng-Yi Yu, Yan-Mei Wang, Tian Tian, Wen-Ming Wu, Ming Zhou, Xiang-Gao Meng, Han-Li Ruan*. Neuroprotective Lignans from the Fruits of Schisandra bicolor var. tuberculata. Journal of Natural Products, 2017, 80 (4), 1117–1124 * Ye Liu, Tian Tian, Heng-Yi Yu, Ming Zhou, Han-Li Ruan*. Nortriterpenoids from the stems and leaves of Schisandra viridis, Fitoterapia, 2017, 118: 38-41 * An Jin, Wen-Ming Wu, Han-Li Ruan*. Sesquiterpenoids and monoterpenoid coumarins from Parasenecio rubescens, Rsc Advances, 2017, 7(9), 5167–5176 * Ye Liu, Yan-Mei Wang, Wen-Ming Wu, Jian Song, Han-Li Ruan*. Triterpenoids and lignans from the fruit of Schisandra sphenanthera. Fitoterapia, 2017, 116:10–16 * Ming Zhou, Ye Liu, Jian Song, Xiao-Gang Peng, Qi Cheng, Hui Cao, Ming Xiang, and Han-Li Ruan*, Schincalide A, a Schinortriterpenoid with a Tricyclo[5.2.1.01,6]decane-Bridged System from the Stems and Leaves of Schisandra incarnate. Organic Letters, 2016, 18 (18), 4558–4561 * Wen-Ming Wu, Xu Chen, Ye Liu, Yan-Mei Wang, Tian Tian, Xiao-Ya Zhao, Juan Li, Han-Li Ruan*. Triterpenoids from the branch and leaf of Abies fargesii. Phytochemistry, 2016, 130, 301–312 * Heng-Yi Yu, Juan Li, Ye Liu, Wen-Ming Wu, Han-Li Ruan*. Triterpenoids from the fruit of Schisandra glaucescens. Fitoterapia, 2016, 113, 64–68. * Wen-Ming Wu, Ye Liu, Xu Chen, An Jin, Ming Zhou, Tian Tian, Han-Li Ruan*, Diterpenoids from the branch and leaf of Abies fargesii, Fitoterapia, 2016, 110: 123-128.

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