项光亚 - 华中科技大学

个人简介

教育部新世纪优秀人才支持计划入选者。现任全国药学教学指导委员会委员，中国高等教育学会医学教育专业委员会药学教育研究分会理事，中国药学会湖北省药物化学专业委员会副主任委员。1990年毕业于华东师范大学化学系，1995年毕业于武汉大学获硕士学位；2000年毕业于同济医科大学获博士学位。先后在德国蒂宾根大学和美国俄亥俄州立大学分别进行为期一年进修访问。

研究领域

现主要从事靶向药物传递系统和药物合成研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Yannan Yang#, Yao Lu#, Prasanna Lakshmi Abbaraju, Jun Zhang, Min Zhang,Guangya Xiang,* and Chengzhong Yu*，Multi-shelled Dendritic Mesoporous Organosilica Hollow Spheres: Roles of Composition and Architecture in Cancer Immunotherapy，Angew. Chem. Int. Ed.,2017,56:8446-8450 Pengxuan Zhao,Shuangping Wu,Yao Cheng,Jia You,Yan Chen,Minsi Li, Chuanchuan He,Xiaojuan Zhang,TanYang,Yao Lu,Robert J. Lee,Xingxing He, Guangya Xiang, MiR-375 delivered by lipid-coated doxorubicin-calcium carbonate nanoparticles overcomes chemoresistance in hepatocellular carcinoma，Nanomedicine: Nanotechnology, Biology, and Medicine，2017，In press. Muhammad Sarfraz#, Attia Afzal1#, Shahid Masood Raza, Sajid Bashir, Asadullah Madni, Muhammad Waseem Khan, Xiang Ma*, Guangya Xiang*，Liposomal co-delivered oleanolic acid attenuates doxorubicin induced multi-organ toxicity in hepatocellular carcinoma，Oncotarget，2017，8(29):47136-47153 Wei Li, Mengzhu Zheng, Shuangping Wu, Suyu Gao, Mei Yang, Zhimei Li, Qiuxia Min1, Weiguang Sun,Lixia Chen*, Guangya Xiang* and Hua Li*，Benserazide, a dopadecarboxylase inhibitor,suppresses tumor growth by targeting hexokinase, Journal of Experimental & Clinic Cancer Research, 2017，36：58 Zhongping Hu, Shasha Zhang, Weicheng Zhou, Xiang Ma*, Guangya Xiang*，Synthesis and antibacterial activity of 3-benzylamide derivatives as FtsZ Inhibitors，Bioorganic & Medicinal Chemistry Letters,2017，27：1854-1858 Tan Yang#，Ling Xu#，Bin Li，Weijie Li，Xiang Ma，Lingling Fan，Robert J Lee，Chuanrui Xu*， Guangya Xiang*，Antitumor activity of a folate receptor-targeted immunoglobulin G-doxorubicin conjugate， Internatioal Journal of Nanomedicine，2017，12：2505-2515 Yongkang Gai#, Lingyi Sun#, Wenqi Hui, Qin Ouyang, Carolyn J. Anderson, Guangya Xiang*, Xiang Ma*, and Dexing Zeng*，New Bifunctional Chelator p‑SCN-PhPr-NE3TA for Copper-64: Synthesis, Peptidomimetic Conjugation, Radiolabeling, and Evaluation for PET Imaging，Inorganic Chemistry，2016，55（14）：6892-6901（IF=4.82） Yao Lu, Yuhua Wang, Lei Miao, Matthew Haynes, Guangya Xiang*, Leaf Huang*, Exploiting in situ antigen generation and immune modulation to enhance chemotherapy response in advanced melanoma: A combination nanomedicine approach，Cancer Letters，2016，379（1）：32–38(IF=5.992) Yongkang Gai, Guangya Xiang, Xiang Ma, Wenqi Hui, Qin Ouyang, Lingyi Sun, Jiule Ding, Jing Sheng, and Dexing Zeng*, Universal Molecular Scaffold for Facile Construction of Multivalent and Multimodal Imaging Probes，Bioconjugate Chemistry，2016，27:515-520（IF=4.513） Lu, Yao; Miao, Lei; Wang, Yuhua; Xu, Zhenghong; Zhao, Yi; Shen, Youqing; Xiang, Guangya*; Huang, Leaf*，Curcumin Micelles Remodel Tumor Microenvironment and Enhance Vaccine Activity in an Advanced Melanoma Model，Molecular Therapy，2016,24（2）：364-374（IF=6.938） Yang, Tan; Zhao, Pengxuan; Rong, Zhao; Li, Bin; Xue, Huiying; You, Jia; He, Chuanchuan; Li, Weijie; He, Xingxing; Lee, Robert J; Ma, Xiang*; Guangya Xiang*，Anti-tumor Efficiency of Lipid-coated Cisplatin Nanoparticles Co-loaded with MicroRNA-375，Theranostics，2016，6(1)：142-154（IF=8.854） Gai, YK；Hu, ZP ; Rong, Z；Ma, X*；Xiang, GY*，A Practical Route for the Preparation of 1,4,7-Triazacyclononanyl Diacetates with a Hydroxypyridinonate Pendant Arm，Molecules，2015，20(10):19393-19405（IF=2.416） Zhang, Wendian; Peng, Fangqi; Zhou, Taotao; Huang, Yifei; Zhang, Li; Ye, Peng; Lu, Miao; Yang, Guang; Gai, Yongkang; Yang, Tan; Ma, Xiang*; Xiang, Guangya*，Targeted delivery of chemically modified anti-miR-221 to hepatocellular carcinoma with negatively charged liposomes，International Journal of Nanomedicine, 2015，10：4825-4836. （IF=4.195） Yifei Huang,* Tan Yang,*Wendian Zhang，Yao Lu，Peng Ye，Guang Yang，Bin Li，Shibo Qi，Yong Liu，Xingxing He，Robert J Lee，Chuanrui Xu*，Guangya Xiang*，A novel hydrolysis-resistant lipophilic folate derivative enables stable delivery of targeted liposomes in vivo，International Journal of Nanomedicine ，2014:9 4581–4595（IF=4.195） Guang Yang, Tan Yang, Wendian Zhang, Miao Lu Xiang Ma,*, and Guangya Xiang*，In Vitro and in Vivo Antitumor Effects of Folate-Targeted Ursolic Acid Stealth Liposome，J. Agric. Food Chem. 2014，62:2207-2215（IF=3.107） Peng Ye，Wendian Zhang，Tan Yang，Yao Lu，Miao Lu，Yongkang Gai，Xiang Ma*，Guangya Xiang*，Folate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting， International Journal of Nanomedicine，2014,9:2167-2178（IF=4.195）