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个人简介

受教育经历(EducationalExperience): 2010/09-2014/06,北京大学,基础医学院,博士 2007/09-2010/06,郑州大学,基础医学院,硕士 2003/09-2007/06,河南大学,药学院,学士。 工作经历(ProfessionalExperience): 2019/01–至今,河南大学,药学院,副教授; 2015/04–2018/12,河南大学,药学院,讲师; 承担项目情况(FinancialSupports) [1]Wnt5b介导P2X3受体上膜的机制及其在骨癌痛中的作用研究,81701110,20万,2018.01-2020.12,国家自然科学基金项目,主持人。 [2]嘌呤能P2X3受体上膜的机制及其在骨癌痛中的作用研究,10万,2018.12-至今,河南省博士后项目一等资助,主持人。 [3]多胺通过蛋白激酶AKT促进肝癌转移,2万,2016.01.01-2017.12,河南省教育厅科学技术研究重点项目,主持人。

研究领域

癌及癌症痛的发病机制。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

[1]DongFang,Ling-YuKong,CaiJie,Ji-ShengHan,Guo-GangXing.IL-6-mediatedfunctionalupregulationofTRPV1receptorsinDRGneuronsviaactivationofJAK/PI3Ksignalingpathway:rolesinthedevelopmentofbonecancerpaininaratmodel,Pain,2015,156(6):1124-1144.(IF=6.02) [2]CongWang,PingRuan,YingZhao,XiaominLi,JunWang,XiaoxiaoWu,TongLiu,ShashaWang,JiuzhouHou,WeiLi,QianLi,JinghuaLi,FujunDai,DongFang*,ChaojieWang*,SongqiangXie*.Spermidine/spermineN1-acetyltransferaseregulatescellgrowthandmetastasisviaAKT/β-cateninsignalingpathwaysinhepatocellularandcolorectalcarcinomacells;Oncotarget;2017,8(1):1092-1109.(IF=5.08) [3]WeiLi,Jiu-ZhouHou,JieNiu,Zhuo-QingXi,ChangMa,HuaSun,Chao-JieWang,DongFang*,QinLi*,Song-qiangXie*..Akt1inhibitionpromotesbreastcancermetastasisthroughEGFR-mediatedβ-cateninnuclearaccumulation;CellCommunicationandSignaling,2018,16(1):82.(IF=5.3) [4]JieNiu,XiaoMengLi,XiaoWang,ChaoLiang,YiDanZhang,HaiYingLi,FanYeLiu,HuaSun,SongQiangXie,DongFang*.DKK1inhibitsbreastcancercellmigrationandinvasionthroughsuppressionofβ-catenin/MMP7signalingpathway;CancerCellInternational;2019,19:168.[IF=3.36] [5]YingZhao,Chao-ChaoGe,JunWang,Xiao-XiaoWu,Xiao-MinLi,WeiLi,Sha-ShaWang,TongLiu,Jiu-ZhouHou,HuaSun,DongFang*,Song-QiangXie*.MEKinhibitor,PD98059,promotesbreastcancercellmigrationbyinducingβ-cateninnuclearaccumulation;OncologyReports;2017,38(5):3055-3063.[IF=3.06] [6]Jiu-ZhouHou,Zhuo-QingXi,JieNiu,WeiLi,XiaoWang,ChaoLiang,HuaSun,DongFang*,Song-qiangXie*.InhibitionofPIKfyveusingYM201636suppressesthegrowthoflivercancerviatheinductionofautophagy;OncologyReports,2018,41(3):1971-1979.[IF=3.06] [7]JieNiu,XiaoWang,ChaoLiang,Yi‐DanZhang,Fan‐YeLiu,Hai‐YingLi,Song‐QiangXie,HuaSun,DongFang*.Suppressionofepidermalgrowthfactorreceptor‐mediatedβ‐cateninnuclearaccumulationenhancestheanti‐tumoractivityofphosphoinositide3‐kinaseinhibitorinbreastcancer;CellBiologyInternational;2019,43(8):931-939.2017;18:2231-2246..[IF=2.12] [8]YingWang,Chen-YangFeng,Hao-YingHe,Jin-JinHe,JunWang,Xiao-MinLi,Sha-ShaWang,WeiLi,Jiu-ZhouHou,TongLiu,DongFang*,Song-QiangXie*.SensitizationofTRPV1receptorsbyTNF-αorchestratesthedevelopmentofvincristine-inducedpain.2018,OncologyLetters,15(4):5013-5019.[IF=1.87]

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