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个人简介

受教育经历(EducationalExperience)(从大学本科开始,按时间倒排序): 2005.3-2009.3天津大学应用化学专业博士研究生 2001.9-2004.6河南中医学院中药专业硕士研究生 工作经历(ProfessionalExperience)(按时间倒排序): 2003.7至今河南大学药学院副教授; 承担项目情况: (1)河南省重点科技攻关项目,132102310026,芳香酰亚胺衍生物合成、生物活性,2013/01-2015/12,5万元,已结题、主持 (2)中国博士后科学基金第四十九批项目,20110490991,萘酰亚胺衍生物合成及其抗肿瘤活性评价,2011/05-2014/11,3万元,已结题,主持。 (3)河南省自然科学与基础前沿项目,112300410181、新型萘酰亚胺衍生物抗肿瘤活性及其作用机制研究,2011/01-2014/10,0万元,已结题,主持

研究领域

1)药物合成;2)小分子与生物大分子相互作用研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

第一作者论文 (1)Tian,Zhiyong,Huang,Yingying,Zhang,Yan,Song,Lina,Qiao,Yan,Xu,Xuejun,Wang,Chaojie,Spectroscopicandmolecularmodelingmethodstostudytheinteractionbetweennaphthalimide-polyamineconjugatesandDNA,JournalofPhotochemistryandPhotobiologyB-Biology,2016.5.01,158:1~15. (2)Tian,Zhi-Yong,Song,Li-Na,Zhao,Yuan,Zang,Feng-Lei,Zhao,Zhong-Hua,Chen,Nan-Hao,Xu,Xue-Jun,Wang,Chao-Jie,SpectroscopicstudyontheInteractionbetweennaphthalimide-polyamineconjugatesandbovineserumalbumin(BSA),Molecules,2015.9.01,20(9):16491~16523. (3)Tian,Zhiyong,Zang,Fenglei,Luo,Wen,Zhao,Zhonghua,Wang,Yuegiao,Xu,Xuejun,Wang,Chaojie,Spectroscopicstudyontheinteractionbetweenmononaphthalimidespermidine(MINS)andbovineserumalbumin(BSA),JournalofPhotochemistryandPhotobiologyB:Biology,2015.1.01,142:103~109. (4)Tian,Zhiyong,Zhao,Zhonghua,Zang,Fenglei,Wang,Yueqiao,Wang,Chaojie,Spectroscopicstudyontheinteractionbetweennaphthalimide-polyamineconjugatesandDNA,JournalofPhotochemistryandPhotobiologyB-Biology,2014.9.5,138:202~210. (5)Tian,Zhi-Yong,Li,Jing-Hua,Li,Qian,Zang,Feng-Lei,Zhao,Zhong-Hua,Wang,Chao-Jie,Studyonthesynthesis,biologicalactivityandspectroscopyofnaphthalimide-diamineconjugates,molecules,2014.6.01,19(6):7646~7668. (6)田智勇,苏雷朋,谢松强,赵瑾,王超杰,萘酰亚胺-多胺缀合物的合成、生物活性和荧光光谱,有机化学,2013.2.01,(07):1514~1521. (7)Tian,Zhi-yong,Xie,Song-qiang,Mei,Zi-hou,Zhao,Jin,Gao,Wen-yuan,Wang,Chao-jie,ConjugationofsubstitutednaphthalimidestopolyaminesascytotoxicagentstargetingtheAkt/mTORsignalpathway,Organic&BiomolecularChemistry,2009.01.01,7(22):4651~4660. (8)Tian,Zhi-yong,Xie,Song-qiang,Du,Yao-wu,Ma,Yuan-fang,Zhao,Jin,Gao,Wen-yuan,Wang,Chao-jie,Synthesis,cytotoxicityandapoptosisofnaphthalimidepolyamineconjugatesasantitumoragents,EuropeanJournalofMedicinalChemistry,2009.1.01,44(1):393~399 (9)Tian,ZhiYong,Ma,HongXia,Xie,SongQiang,Wang,Xue,Zhao,Jin,Wang,ChaoJie,Gao,WenYu,Synthesis,DNAbindingandtopoisomeraseinhibitionofmononaphthalimidehomospermidinederivatives,ChineseChemicalLetters,2008.5.01,19(5):509~512. (10)Tian,Zhi-Yong,Du,Gang-Jun,Xie,Song-Qiang,Zhao,Jin,Gao,Wen-Yuan,Wang,Chao-Jie,Synthesisandbioevaluationof5-fluorouracilderivatives,Molecules,2007.11.01,12(11):2450~2457. (11)ZhiyongTian,LuyaoZhao,HuanyangDong,YanZhang,YijuanZhang,QianleiRen,ShuangyuShao,YingyingHuang,LinaSong,TaoGuo,XuejunXu,ChaojieWang,Studyontheinteractionofanthracenyl-methylhomospermidineconjugate(ANTMHspd)withDNAbyspectroscopicmethods,JournalofPhotochemistryandPhotobiologyB:Biology,2017.03.02,169:27~34

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