张兰桐 - 河北医科大学

个人简介

药学院药物分析教研室主任。享受河北省政府特殊津贴专家，河北医科大学学术带头人，中国药学会药物分析专业委员会委员，河北省药学会理事，药物分析与天然药物专业委员会副主任委员，河北省中医药学会理事，河北省新药评审专家；药物分析杂志、中草药杂志、河北医科大学学报编委等。

研究领域

主要从事药品质量控制研究，从事化学药物和天然药物中有效成分与体内药物分析的研究，以及药物代谢和中药指纹（特征）图谱研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Investigating the in vitro stereoselective metabolism of m-nisoldipine enantiomers: Characterization of metabolites and cytochrome P450 isoforms involved. Biomedical Chromatography，2015，29（12）：1893–1900. SCI收录，IF=1.876. 通讯作者 2. Simultaneous quantification of 16 bioactive constituents in Common cnidium fruit by liquid chromatography–electrospray ionization-mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis，107 (2015) 304–310. SCI收录，IF=1.876. 通讯作者 3. LC–MS/MS determination and pharmacokinetic study of seven flavonoids in rat plasma after oral administration of Cirsiumjaponicum DC. Extract. Journal of Ethnopharmacology，158（2014）66–75. SCI收录，IF=3.055. 通讯作者 4. A sensitive analysis method for 7 diterpenoids in rat plasma by liquid chromatography–electrospray ionization mass spectrometry and its application to pharmacokinetic study of Isodonserra extract. Journal of Chromatography A 1218 (2011) 7771–7780. SCI收录，IF=4.531. 通讯作者 5. Development of a novel method for triterpenoidalsaponins in rat plasma by solid-phase extraction and high-performance liquid chromatography tandem mass spectrometry. Analytical Biochemistry，419 (2011) 323–332. SCI收录，IF=3.236. 通讯作者 6. A rapid method for simultaneous determination of triterpenoidsaponins in Pulsatillaturczaninovii using microwave-assisted extraction and high performance liquid chromatography - tandem mass spectrometry. Food Chemistry，135 (2012) 251–258. SCI收录，IF=3.458，通讯作者 7. Determination of Cnidilin and Its Two Metabolites in Rat Plasma by High-performance Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry. Plata Medica，2013; 79: 30–36，SCI收录，IF=1.863. 通讯作者 8. Determination of cnidilin and its two metabolites in rat bile and stool after oral administration by HPLC/electrospray ionization tandem mass spectrometry. Biomedical Chromatography，2013; 27: 527–534. SCI收录，IF=1.762. 通讯作者 9. Simultaneous determination and pharmacokinetic study of six flavonoids from FructusSophorae extract in rat plasma by LC–MS/MS. Journal of Chromatography B, 904 (2012) 59– 64. SCI收录，IF=2.885. 通讯作者 10. Simultaneous determination of nine components in Anemarrhenaasphodeloides by liquid chromatography-tandem mass spectrometry combined with chemometric techniques. Journal of Separation Science，2012, 35, 1796–1807. SCI收录，IF=2.786. 通讯作者