个人简介
2013年于贵州大学硕博连读获得理学博士学位后进入贵州省中国科学院天然产物化学重点实验室(药用植物功效与利用国家重点实验室)工作,负责肿瘤药理实验室的日常管理工作,并担任药理与活性筛选中心主任助理。2016年12月,在首都医科大学完成博士后研究工作。入选了中国科学院“西部青年学者”培养计划、中组部“西部之光”访问学者计划。
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[1] Li YJ.#, Luo H. #, Zacksenhaus, E., and Ben-David, Y*. The ets transcription factor in development, cancer and diseases. Oncogene, 2015, 34:2022–2031 [2]Huang LR#, Luo H#, Yang XS*, Chen L, Hao XJ. Enhancement of anti-bacterial and -tumor activities of pentacyclic triterpenes by introducing exocyclic α, β-unsaturated ketone moiety in ring A. Medicinal Chemistry Research, 2014, 23:4631–4641. [3]Lei Xia, Yu-Fen Xia, Li-Rong Huang, Xiao Xiao, Hua-yong Lou, Tang-Jingjun Liu, Wei-Dong Pan*, Heng Luo*. Benzaldehyde Schiff bases regulation to the metabolism, hemolysis, and virulence genes expression in vitro and their structure-microbicidal activity relationship [J]. European Journal of Medicinal Chemistry, 2015, 97 (2015) 83-93 [4] Li-Rong Huang, Xiao-Jiang Hao, Qi-Ji Li, Jian-Xin Zhang, Dao-Ping Wang, Heng Luo*, Xiao-Sheng Yang*. 18β-Glycyrrhetinic Acid Derivatives Possessing a Polyhydroxyl A-ring as Potent Gram-positive Bacteria Inhibitors. Journal of Natural Products, 2016, 79, 721−731 [5] Zheng-Ming Liang#, Xing-Hui Wang#, Li-Rong Huang, Qi-Ji Li, Tian-Qi Guan, Xiao-Jiang Hao, Heng Luo*, Xiao-Sheng Yang*. 1α, 2α-Epoxy -3b-hydroxy oleanolic acid derivatives regulation of the metabolism, haemolysis and b-lactamase gene expression in vitro and their structure–microbicidal activity relationship. Bioorganic & Medicinal Chemistry Letters, 2016, 26:3870–3875. [6]Chen Yan#, Yun-Dong Zhang #, Xing-Hui Wang, Shun-Dong Geng, Tian-Yuan Wang, Mao Sun, Wei Liang, Wei-Qing Zhang, Xiao-Dong Zhang*, Heng Luo*. Tirucallane-type triterpenoids from the fruits of Phellodendron chinense Schneid and their cytotoxic activities. Fitoterapia, 2016, 113(2):132-138 [7] Li-li Fang#, Bao-fei Sun#, Li-rong Huang, Hai-bo Yuan, Shuo Zhang, Jing Chen, Zi-jiang Yu* and Heng Luo*. Potent Inhibition of miR-34b on Migration and Invasion in Metastatic Prostate Cancer Cells by Regulating the TGF-β Pathway[J]. Int. J. Mol. Sci. 2017, 18, 2762. [8]Li-li Fang#, Xing-hui Wang#, Bao-fei Sun, Xiao-dong Zhang, Xu-hui Zhu, Zi-jiang Yu* and Heng Luo*. Expression, regulation and mechanism of action of miR-17-92 cluster in tumor cells. International Journal of Molecular Medincine, 2017, 40: 1624-1630 [9] Heng Luo#, Yu-fen Xia#, Bao-fei Sun, Li-rong Huang, Xing-hui Wang, Hua-yong Lou, Xu-hui Zhu,Wei-dong Pan*, Xiao-dong Zhang*. Synthesis and Evaluation of In Vitro Antibacterial and Antitumor Activities of Novel N,N-Disubstituted Schiff Bases. BioMed Research International, 2017, 2017:1-10. [10]Zhonghang Wen, Yongqiang Zhang, Xinghui Wang, Xiaoping Zeng, Zhanxing Hu,Yi Liu, Yuxin Xie, Guangyi Liang, Jianguo Zhu*, Heng Luo*, Bixue Xu*.Novel 3’,5’-diprenylated chalcones inhibited the proliferation of cancer cells in vitro by inducing cell apoptosis and arresting cell cycle phase. European Journal of Medicinal Chemistry, 2017,133:227-239. [11]Yong-Qiang Zhang, Zhong-Hang Wen, Ke Wan, Dongbo Yuana, Xiaoping Zeng, Guangyi Liang, Jianguo Zhu⁎, Bixue Xu⁎, Heng Luo⁎. A novel synthesized 3’, 5’-diprenylated chalcone mediates the proliferation of human leukemia cells by regulating apoptosis and autophagy pathways [J]. Biomedicine & Pharmacotherapy, 106 (2018):794–804.