杨元勇 - 贵州医科大学

个人简介

2007年毕业于四川大学获学士学位，2012年毕业于新加坡国立大学获哲学博士学位，2012年到2014年在新加坡国立大学化学生物学从事博士后研究工作，2014年下学期进入贵州医科大学药物化学教研室工作，现任药学科学中心副主任。

研究领域

主要从事有机不对称催化的方法学研究和鲍曼不动杆菌生物膜抑制剂的开发。不对称催化包括药物活性分子的路线设计，不对称合成和工艺开发等。细菌的生物膜是细菌耐药和院内感染的主要形式，对生物膜抑制剂的开发会极大程度上减轻细菌耐药和院内感染，基于此方法的抗菌材料有很好的发展前景。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Yuanyong Yang, Yingxian Li, Cheng Cheng, Guo Yang, Jiquan Zhang, Yi Zhang, Yonglong Zhao, Lin Zhang, Chun Li,* Lei Tang* Synthesis of 4‑Aryl Isoquinolinedione Derivatives by a Palladium-Catalyzed Coupling Reaction of Aryl Halides with Isoquinoline-1,3(2H,4H)‑diones. J. Org. Chem. 2018, 83, 3348−3353. (IF:4.849) 2. Shun Zhou, Lin Zhang, Chun Li, Yuanhu Mao, Jianta Wang, Ping Zhao, Lei Tang*, Yuanyong Yang* Pentanidiumcatalyzed enantioselective hydroperoxidation of 2-oxindole using molecular oxygen. Catalysis Communication, 2016, 82, 29-31. (IF:3.389) 3. Jeng Yeong Chow, Yuanyong Yang, Song Buck Tay, Kim Lee Chua, Wen Shan Yew* Disruption of Biofilm Formation by the Human Pathogen Acinetobacter baumannii Using Engineered Quorum-Quenching Lactonases. Antimicrobial Agents and Chemotherapy, 2014, 58, 1802–1805. (IF:4.302) 4. Yang Yuanyong, Chua Kim Lee. Assessment of efflux pump inhibitors on in vitro antimicrobial susceptibility of multidrug resistant Acinetobacter baumannii. Int. J. Antimicrob. Ag. 2013, 42, 283–284. (IF: 4.259) 5. Richmond Lee#, Yuanyong Yang#, Geok Kheng Tan, Choon-Hong Tan, Kuo-Wei Huang. A novel heteroleptic paddlewheel diruthenium bicyclic guanidinate complex: synthesis, structure, and scope. Dalton Trans.,2010, 39, 723 – 725. (IF: 4.08) 6. Yuanyong Yang, Farhana Moinodeen, Chin Willy, Ting Ma, and Choon-Hong Tan. Pentanidium–Catalyzed Enantioselective α-Hydroxylation of Oxindoles Using Molecular Oxygen. Org. Lett. 2012, 14, 4762–4765. (IF: 6.142) 7. Zhiyong Jiang, Yuanyong Yang, Yuanhang Pan, Yujun Zhao, Hongjun Liu, Choon-Hong Tan. Synthesis of alpha-Stereogenic Amides and Ketones via Enantioselective Conjugate Addition of 1,4-Dicarbonyl But-2-enes. Chem. Eur. J. 2009, 15, 4925 – 4930. (IF: 5.696) 8. Zhiyong Jiang, Yuanhang Pan, Yujun Zhao, Ting Ma, Richmond Lee,Yuanyong Yang, Kuo-Wei Huang, Ming Wah Wong, Choon-Hong Tan. Synthesis of a Chiral Quaternary Carbon Center Bearing a Fluorine Atom: Enantio- and Diastereoselective Guanidine-Catalyzed Addition of Fluorocarbon Nucleophiles. Angew. Chem. Int. Ed. 2009, 121, 3681 – 3685. (IF: 11.829) 9.Yuanhang Pan, Yujun Zhao, Ting Ma, Yuanyong Yang, Hongjun Liu, Zhiyong Jiang, Choon-Hong Tan. Enantioselective Synthesis of alpha-Fluorinated beta-Amino Acid Derivatives by an Asymmetric Mannich Reaction and Selective Deacylation/Decarboxylation Reactions. Chem. Eur. J. 2010, 16, 779 – 782. (IF: 5.696) 10.Jianmin Wang, Hongjun Liu, Yitian Fan, Yuanyong Yang, Zhiyong Jiang, Choon-Hong Tan. Bicyclic Guanidine-Catalyzed Direct Asymmetric Allylic Addition of N-Aryl Alkylidene-Succinimides. Chem. Eur. J. 2010, 16, 12534 – 12537. (IF: 5.696) 11.Yujun Zhao, Yuanhang Pan, Hongjun Liu, Yuanyong Yang, Zhiyong Jiang, Choon-Hong Tan. Fluorinated Aromatic Ketones as Nucleophiles in the Asymmetric Organocatalytic Formation of C–C and C–N Bonds: A Facile Route to the Construction of Fluorinated Quaternary Stereogenic Centers. Chem. Eur. J. 2011, 17, 3571 – 3574. (IF: 5.696)