个人简介
自2007年以高层次人才引进方式进入贵州省中国科学院天然产物化学重点实验室从事科研工作以来,一直从事天然药物化学相关的一线科研工作,2013年破格晋升为研究员,创新药物研究中心副主任。
研究领域
1、药用植物(包括中药和民族药)中物质基础的提取、分离纯化、结构鉴定、生物功能及其质量控制标准的研究;2、基于植物化学防御特性研发新型农药;3、活性天然产物的结构修饰及其构效关系的研究。
近期论文
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1. Jiaqi Fang, Tao Huang, MengyuanXia, Lulu Deng, XiaojiangHao, Yuehu Wang, and Shuzhen Mu*. Design and synthesis of novel monoterpenoid indole alkaloids-like analogues and their antitumour activities in vitro[J]. Organic & Biomolecular Chemistry, 2018, 16, 3026-3037. 2. Qingyao Wang; Jiaqi Fang; Lulu Deng; Xiaojiang Hao; Shuzhen Mu*. Regioselective alkali metal reduction of dibenzocyclooctadiene lignan derivatives, demethoxylation followed by dehalogenation[J]. Chemistry Central Journal 2017, 11: 138-146. 3. Qing-Yao Wang, Lu-Lu Deng, Jia-Ju Liu, Jian-Xin Zhang, Xiao-Jiang Hao, Shu-Zhen Mu*. Schisanhenol derivatives and their biological evaluation against tobacco mosaic virus (TMV)[J]. Fitoterapia, 2015, 101(3): 117-124. 4. Tao He, Qing-Yao Wang, Jing-Zhen Shi, Tian-Yun Fan, Chen Yan, Lie-Jun Huang, Sheng Liu, Xiao-Jiang Hao*, and Shu-Zhen Mu*. Synthesis and the hepatoprotective activity of dibenzocyclooctadiene lignan derivatives[J]. Bioorganic Medicine Chemistry. Letters 2014, 24(7): 1808-1811. 5. Lin Chen, Jian-Xin Zhang, Bin Wang, Shu Zhen Mu*, Xiao-Jiang Hao*. Triterpenoids with Anti-Tobacco Mosaic Virus Activities from Melia Toosendan[J]. Fitoterapia, 2014, 97(9): 204-210. 6. Shu-Zhen Mu, Chun-Rong Jiang, Tao Huang, and Xiao-Jiang Hao*. Two New Rosane-type Diterpeniods from Euphorbia ebracteolata Hayata[J]. Helvetica Chimica Acta 2013, 96 (12): 2299-2303.