Best, Michael D. - The University of Tennessee Knoxville

个人简介

B.S., Boston College (1997) Ph.D., The University of Texas at Austin (2002) NSF CAREER Awardee Ziegler Professorship

研究领域

Chemistry & Life Sciences, Synthetic Chemistry

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Best, M.D. Global approaches for the elucidation of phosphoinositide-binding proteins. Chem. Phys. Lipids In Press. Bayer, A.M.; Alam, S.; Mattern-Schain, S.I.; Best, M.D. Triggered release of molecular cargo from liposomes via a phosphatidylcholine analog bearing a photocleavable moiety embedded within the sn-2 acyl chain. Chem. Eur. J. 2014, 20(12), 3350-3357. Cutulle, M.A.; Armel, G.R.; Brosnan, J.T.; Best, M.D. Kopsell, D.A.; Bruce, B.D.; Bostic, H.E.; Layton, D.D. Synthesis and evaluation of heterocyclic analogs of bromoxynil. J. Agr. Food Chem. 2014, 62, 329-336. Chen, J.; Lambert, J.; Buonaugurio, A.; Bowen, K.H.*; Do-Thanh, C.-L.; Wang, Y.; Best, M.D.; Compton, B.; Sommerfeld, T. Combined photoelectron, collision-induced dissociation, and computational studies of parent and fragment anions of N-paranitrosulfophenysulfonylalanine and N-paranitrophenylalanine. J. Chem. Phys. 2013, 139, 224308. Wang, D.; Zhu, W.; Best, M.D.; Camden, J.P.; Crozier, K.B. Wafer-scale metasurface for total power absorption, local field enhancement and single molecule Raman spectroscopy. Scientific Reports 2013, 3, doi:10.1038/srep02867. Thomas, J.W.; Armel, G.R.; Best, M.D.; Brosnan, J.T.; Klingeman, W.E.; Kopsell, D.A.; Bostic, H.E.; Vargas, J.J.; Do-Thanh, C.-L. Herbicidal activity of heterocyclic dichlobenil analogues. J. Pest. Sci. 2013, 38(4), 220-222. Crozier, K.B.; Zhu, W.; Wang, D.; Lin, S.; Best, M.D.; Camden, J.P. Plasmonics for surface enhanced raman scattering: Nanoantennas for single molecules. J. Sel. Top. Quant. Elect. 2014, 20(3), Article#: 7300311, DOI: 10.1109/JSTQE.2013.2282257. Liu, L.; Xie, H.; Bostic, H.E.; Jin, L.; Best, M.D.; Zhang, X.P.; Zhan, W. Effects of oriented surface dipole on photoconversion efficiency in an alkane/lipid-hybrid-bilayer-based photovoltaic model system. ChemPhysChem, 2013, 14(12), 2777-2785. Milojevich, C.B.; Mandrell, B.K.; Turley, H.K.; Iberi, V.; Simmons, P.D.; Best, M.D.; Camden, J.P. Surface-enhanced hyper-Raman scattering from single molecules. J. Phys. Chem. Lett. 2013, 4, 3420-3423. Wang, D.; Zhu, W.; Best, M.D.; Camden, J.P.; Crozier, K.B. Directional Raman scattering from single molecules in the feed gaps of optical antennas. Nano Lett. 2013, 13(5), 2194-2198. Best, M.D.* The development and application of clickable lipid analogs for elucidating lipid function. Click Chemistry in Glycoscience: New Developments and Strategies. Wiley and Sons, editors: Zbigniew Witczak and Roman Bielski. 2013. 79-107. Mirsaleh-Kohan, M.; Iberi, V.; Simmons, P.D.; Bigelow, N.W.; Vaschillo, A.; Rowland, M.M.; Best, M.D.; Pennycook, S.J.; Masiello, D.J.; Guiton, B.S.; Camden, J.P. Single-molecule surface-enhanced raman scattering: can STEM/EELS image electromagnetic hot spots? J. Phys. Chem. Lett. 2012, 3, 2303-2309. Bostic, H.E.; Smith, M.D.; Poloukhtine, A.A.; Popik, V.V.; Best, M.D. Membrane labeling and immobilization via copper-free click chemistry. Chem. Commun. 2012, 48, 1431-1433. Rowland, M.M.; Bostic, H.E.; Gong, D.; Lucas, N.; Cho, W.; Best, M.D. Microarray analysis of Akt PH domain binding employing synthetic biotinylated analogs of all seven phosphoinositide headgroup isomers. Chem. Phys. Lipids 2012, 165, 207-215. Do-Thanh, C.-L.; Khanal, N.; Lu, Z.; Cramer, S.A.; Jenkins, D.M.*; Best, M.D.* Chloride binding by a polyimidazolium macrocycle detected via fluorescence, NMR and X-ray crystallography. Tetrahedron 2012, 68, 1669-1673. Rowland, M.M.; Bostic, H.E.; Gong, D.; Speers, A.E.; Lucas, N.; Cho, W.; Cravatt, B.F. Best, M.D. Phosphatidylinositol (3,4,5)-trisphosphate activity probes for the labeling and proteomic characterization of protein binding partners. Biochemistry. 2011, 50, 11143−11161. Scott, J.L.; Gong, D.; Ali, M.; Best, M.D.; Prestwich, G.D.; Stahelin R.V.; Kutateladze, T.G. Metabolically stabilized derivatives of phosphatidylinositol 4-phosphate: Synthesis and applications. Chem. Biol. 2011, 18, 1312-1319. Kooijman, E.E.; Kuzenko, S.R.; Gong, D.; Best, M.D.; Folkesson, H.G. Phophatidylinositol-4,5-bisphosphate stimulates alveolar epithelial fluid clearance in male and female adult rats. Am. J. Physiol.-Lung Cell. Mol. Physiol. 2011, 301, L804–L811. Best, M.D.* Recent developments in the generation and application of lipid probes. ASBMB Today 2011, August edition, 28-29. Best, M.D.*; Rowland, M.M.; Bostic, H.E. Exploiting bioorthogonal chemistry to elucidate protein-lipid binding interactions and other biological roles of phospholipids. Acc. Chem. Res. 2011, 44(9), 686–698. Smith, M.D.; Best, M.D.* Characterization of protein–membrane binding interactions via a microplate assay employing liposome immobilization. Bioconjugation Protocols, 2nd edition, Editor: Sonny S. Mark. 2011, 477-489. Do-Thanh, C.-L.; Rowland, M.M.; Best, M.D.* Fluorescent bis-cyclen tweezer receptors for inositol (1,4,5)-trisphosphate. Tetrahedron 2011, 67, 3803-3808. Bolen, A.L.; Naren , A.P.; Yarlagadda, S.; Beranova-Giorgianni, S.; Chen, L. Norman, D.; Baker, D.L.; Rowland, M.M.; Best, M.D.; Sano T., Tsukahara, T.; Liliom, K.; Igarashi, Y.; Tigyi, G.* The phospholipase A 1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation. J. Lipid Res. 2011, 52, 958-970. Rowland, M.M.; Best, M.D.* Reeling in the Catch: Advancing Cleavable Linkers for Proteomics. Chem. Biol. 2010, 17, 1166-168. (Invited preview article).