Wilson, ‌Alex - University of Miami

个人简介

PERT Postdoctoral fellow, 2003-2006, University of Arizona Postdoctoral fellow, 2000-2003, University of California, Davis Ph.D. 2001 Biology, Macquarie University, Australia Visiting fellow, 1998-2000, The Australian National University, Australia

研究领域

My research focuses on characterizing the mechanisms that metabolically and developmentally integrate hosts and symbionts. Symbioses are mutually beneficial interactions between species. They are so beneficial that they are everywhere - in fact you comprise ten symbiotic bacterial cells for every human cell and those bacteria are important determinants of your phenotype, the ability of your body to heal wounds, and digest food. A compelling challenge in symbiosis research concerns identifying and characterizing the mechanisms of host/symbiont integration. I lead a research group that uses symbiotic partnerships involving one host interacting with one, or at most two, symbionts to identify fundamental design principles in the evolution of symbiosis.

近期论文

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Lu HL, Price DRG, Wikramanayake A, Chang CC, Wilson ACC (2016) Ontogenetic differences in localization of glutamine transporter ApGLNT1 in the pea aphid demonstrate that mechanisms of host/symbiont integration are not similar in the maternal versus embryonic bacteriome. EvoDevo, DOI: 10.1186/s13227-015-0038-y. Wilson ACC, Duncan RP (2015) Signatures of host/symbiont genome coevolution in insect nutritional endosymbioses. Proceedings of the National Academy of Science, USA, 112(33):10255-10261. Price DRG, Wilson ACC (2014) A substrate ambiguous enzyme facilitates genome reduction in an intracellular symbiont. BMC Biology 12:110. Duncan RP, Husnik F, Van Leuven JT, Gilbert DG, Dávalos LM, McCutcheon JP, Wilson ACC (2014) Dynamic recruitment of amino acids transporters to the insect-symbiont interface. Molecular Ecology, 23(6): 1608-1623. Price DRG, Feng H, Baker JD, Bavan S, Luetje CW, Wilson ACC (2014) Aphid amino acid transporter regulates glutamine supply to intracellular bacterial symbionts. Proceedings of the National Academy of Sciences of the United States of America, 111, 320-325. Jiang Z, Jones DH, Khuri S, Tsinoremas NF, Wyss T, Jander G, Wilson ACC (2013) Comparative analysis of genome sequences from four strains of the Buchnera aphidicola Mp endosymbiont of the green peach aphid, Myzus persicae. BMC Genomics, 14, 917. Wilson ACC, Sternberg LdSL, Hurley KB (2011) Aphids alter host-plant nitrogen isotope fractionation. Proceedings of the National Academy of Sciences of the United States of America 108, 10220-10224. Wilson ACC, Ashton PD, Calevro F, Charles H, Colella S, Febvay G, Jander G, Kushlan PF, Macdonald SJ, #Schwartz JF, Thomas GH, Douglas AE (2010) Genomic insight into the amino acid relations of the pea aphid Acyrthosiphon pisum with its symbiotic bacterium Buchnera aphidicola. Insect Molecular Biology 19, 249-258.