Langford, Melanie - Florida Southern College

个人简介

I am originally from the Midwest, and have always been interested in science in general. I have always held a great personal interest in marine biology, but also became fascinated with microbiology. I obtained my B.A. from the University of Kansas, my M.S. from the University of South Alabama, and my Ph.D. from the University of Nebraska-Lincoln before coming to FSC as an Adjunct Professor and finally as an Assistant Professor at FSC. I have a very strong background in pathogenic microbiology, and I apply that background to my current work studying the microbial flora of the manatee digestive system. My favorite part about working at FSC is that I can combine my two greatest interests: marine biology and microbiology. I enjoy dance and the performing arts, yoga, hiking, and pretty much any ocean-related activity you can think of such as kayaking, trips to the beach, snorkeling, diving, etc. 2005-2010 – Ph.D. Microbiology – University of Nebraska-Lincoln. 2003-2005 – M.S. Biology (Emphasis in Microbiology) – University of South Alabama 1999- 2003 – B.A. Microbiology. University of Kansas.

研究领域

I have worked with biology students and biology honors students on projects such as studying the bacterial composition of the manatee digestive tract. I have a collaboration with the Marine Mammal Pathobiology Laboratory (MMPL) in St. Petersburg, a facility that performs necropsies on deceased manatees, and upon obtaining a permit from the Florida Fish and Wildlife Conservation Commission, I have been able to obtain samples from these manatees for my research. I have also been able to arrange student visits to observe some of these necropsies thanks to the collaborative efforts of the wonderful researchers at the MMPL. Lastly, I am working on a project with students and my fellow biology faculty members studying the evolutionary relationship between different populations of green anoles in Florida.

近期论文

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Langford, M.L., Shelby Cain, Jalen Howard, Martine de Wit. Isolation of multidrug-resistant bacteria from the Florida manatee, Trichechus manatus latirostris. In Prep. Langford, M.L., Hargarten, J.C., Patefield, K.D., Marta, E., Blankenship, J.R., Fanning, S., Nickerson, K.W., Atkin, A.L. Candida albicans Czf1 and Efg1 coordinate response to farnesol during quorum sensing, white-opaque thermal dimorphism, and cell death. Eukaryotic Cell. 2013. Sep;12(9):1281-92. Kim, S.H., Langford, M.L., Boucher, J.L., Testerman, T.L., McGee, D.J. Helicobacter pylori arginase mutant colonizes arginase II knockout mice. World J Gastroenterol. 2011. Jul 28;17(28):3300-9. Langford, M.L., Hasim, S., Nickerson, K.W., Atkin, A.L. Activity and toxicity of farnesol towards Candida albicans are dependent on growth conditions. Antimicrob Agents Chemother. 2010. Feb;54(2):940-2. Langford, M.L., Atkin, A.L., Nickerson, K.W. Cellular interactions of farnesol, a quorum-sensing molecule produced by Candida albicans. Future Microbiol. 2009. Dec;4(10):1353-62. Kebaara, B.W*., Langford, M.L.*, Navarathna, D.H., Dumitru, R., Nickerson, K.W., Atkin, A.L. Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous growth induction. Eukaryot Cell. 2008. Jun;7(6):980-7. Hovey, J.G., Watson, E.L., Langford, M.L., Hildebrandt, E., Bathala, S., Bolland, J.R., Spadafora, D., Mendz, G.L., McGee, D.J. Genetic microheterogeneity and phenotypic variation of Helicobacter pylori arginase in clinical isolates. BMC Microbiol. 2007. Apr 4;7:26. Langford, M.L., Zabaleta, J., Ochoa, A.C., Testerman, T.L., McGee, D.J. In vitro and in vivo complementation of the Helicobacter pylori arginase mutant using an intergenic chromosomal site. Helicobacter. 2006. Oct;11(5):477-93. McGee, D.J., Langford, M.L., Watson, E.L., Carter, J.E., Chen, Y.T., Ottemann, K.M. Colonization and inflammation deficiencies in Mongolian gerbils infected by Helicobacter pylori chemotaxis mutants. Infect Immun. 2005. Mar:73(3):1820-7.