Ramella-Roman, Jessica - Florida International University - Department of Biomedical Engineering

个人简介

Jessica C. Ramella-Roman received an Electrical Engineering degree (Laurea) from the University of Pavia, Italy in 1993 and worked for five years in the semiconductor industry. She returned to academia in 1999 to pursue a Ph.D. degree in bio-optics with Dr. Steve Jacques and she received a Master's and Ph.D. degree in Electrical Engineering from Oregon Health Science University in Portland, Oregon in 2004. She was a Post Doctoral Fellow at the Applied Physics Laboratory of the Johns Hopkins University from 2004 to 2005. She was then an Associate Professor at The Catholic University of America from 2005 to 2010 and an Associate Professor from 2010 to 2013. She is a Senior Research Scientist at the National Rehabilitation Hospital in Washington DC, and an Adjunct Professor in the School of Medicine at Johns Hopkins University. Since 2013, she has served an Associate Professor at Florida International University, in the Biomedical Engineering Department and an Associate Professor on the Research Scientist Track in the Department of Cellular Biology and in the Department of Ophthalmology. Her current research interests include the use of spectroscopic methodologies for retinal oximetry and flow for the detection of early signs of eye disease. She is also pursuing research on skin damage and recovery including skin burns, pressure wounds, and damage associated to spinal cord injury. She has developed fiber-optic probes as well as spectroscopic and polarimetric imaging devices for this application.

研究领域

Bio-photonics is a line of research that encompasses multiple disciplines, including physics, mathematics, biology, and engineering. The Medical Photonics Laboratory (MPL) at FIU conducts research in bio-photonics and focuses particularly on the development of devices and methodologies for diagnosis of disease. We focus on the detection of early signs of Diabetic Retinopathy, a disease associated with diabetes, using spectroscopic and polarimetric techniques. We are also developing methodologies for non-invasive monitoring of the skin. We are conducting research on the discrimination of melanoma, one of the most dangerous forms of skin cancer, and we are seeking insights into several forms of skin damage including pressure damage, thermal damage, and electrical damage.

近期论文

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Yinchen Song, Jessica C. Ramella-Roman, Mohammad Soltani and Wei-Chiang Lin, “Quantitative assessment of hemodynamic and structural characteristics of in vivo brain tissue using total diffuse reflectance spectrum measured in a non-contact fashion,” Biomedical Optics Express, Vol. 8, Issue 1, pp. 78-103 (2017) J. Chue-Sang, Y. Bai, S. Stoff, D. Straton, S. Ramaswamy, J. C. Ramella-Roman, “Use of a combined polarization-sensitive optical coherence tomography system and Mueller matrix imaging polarimetry for the polarimetric characterization of excised biological tissue,” J. Biomed. Opt. 21(7) 071109 doi: 10.1117/1.JBO.21.7.071109, (2016) Rincon K, Shah P, Ramella-Roman J, Bhansali S., “A Review of Engineering Approaches for Lymphedema Detection.,” IEEE Rev Biomed Eng.;9:79-90. doi: 10.1109/RBME.2016.2582178. Epub 2016 Jun 20. (2016) Daniel Rodriguez, Pedro Lopez, Jessica C. Ramella-Roman, “A Monte Carlo Analysis of Error Associated With Two-Wavelength Algorithms for Retinal Oximetry,” Investigative Ophthalmology & Visual Science November, Vol.57, 6474-6481. doi:10.1167/iovs.16-20138 (2016) Md Ashfaq Ahmed, Yuqiang Bai, J.C. Ramella-Roman, R. Jung, “Neurophotonics for peripheral nerves”, Textbook of NeuroPhotonics and Brain Mapping, Taylor and Francis, (2016) P. Ghassemi, L. T. Moffatt, J. W. Shupp and J.C. Ramella-Roman, “A new approach for optical assessment of directional anisotropy in turbid media,” Journal of Biophotonics, 9999, 10.1002/jbio.201400124, (2015) D. W. Paul, P. Ghassemi, Jessica C. Ramella-Roman, N. Prindeze, L. T. Moffatt, A. Alkhalil; and J. W. Shupp, “Noninvasive Imaging Technologies for Cutaneous Wound Assessment: A Review,” Wound Repair and Regeneration 10.1111/wrr.12262, (2015) A. Alkhalil, S. Tejiram, MD, T. E. Travis, MD, N. J. Prindeze, B. C. Carney, L. T. Moffatt, L. S. Johnson, J. C. Ramella-Roman, and J. W. Shupp, “A Translational Animal Model for Scar Compression Therapy Using an Automated Pressure Delivery System,” Eplasty. 15: e29, (2015) P. Ghassemi, J. Wang, A. J. Melchiorri, J. C. Ramella-Roman, S. A. Mathews, J. C. Coburn, B. S.Sorg, Y. Chen, and J. Pfefera “Rapid prototyping of biomimetic vascular phantoms for hyperspectral reflectance imaging”, In J. Biomed. Opt. 20(12) 121312 doi: 10.1117/1.JBO.20.12.121312, (2015) Pejhman Ghassemi, Taryn E. Travis, Lauren T. Moffatt, Jeffrey W. Shupp, and Jessica C. Ramella-Roman, "A polarized multispectral imaging system for quantitative assessment of hypertrophic scars," Biomedical Optics Express, Vol. 5, Issue 10, pp. 3337-3354 (2014) http://dx.doi.org/10.1364/BOE.5.003337 Taryn E. Travis, Pejhman Ghassemi, Jessica C. Ramella-Roman, Nicholas J. Prindeze, Dereck W. Paul, Lauren T. Moffatt, Marion H. Jordan, Jeffrey W. Shupp, "A Multi-Modal Assessment of Melanin and Melanocyte Activity in Abnormally Pigmented Hypertrophic Scar," The Journal of burn care & rehabilitation (2014) Du V. N. Le, Quanzeng Wang, Taylor Gould, Jessica C. Ramella-Roman and T. Joshua Pfefer, “Vascular Contrast in Narrow Band and White Light Imaging,” Applied Optics, Vol. 53, Issue 18, pp. 4061-4071 (2014) http://dx.doi.org/10.1364/AO.53.004061 Jianting Wang, James Coburn, Chia-Pin Liang, Nicholas Woolsey, Jessica C. Ramella-Roman, Yu Chen, and T. Joshua Pfefer, “Three-Dimensional Printing of Tissue Phantoms for Biophotonic Imaging," Optics Letters, Vol. 39, Issue 10, pp. 3010-3013 (2014) Mamdouh Aloraefy, T. Joshua Pfefer, Jessica C. Ramella-Roman and Kim E. Sapsford, "In Vitro Evaluation of Fluorescence Glucose Biosensor Response," Sensors 2014, 14(7), 12127-12148; doi:10.3390/s140712127 Xuan Liu, Jessica C. Ramella-Roman, Jin Kang, “Robust spectral-domain optical coherence tomography speckle model and its cross-correlation coefficient analysis,” JOSA A 30, 1, 51–59 (2013) Xuan Liu, Yong Huang, Jessica C. Ramella-Roman, Scott A. Mathews, and Jin U. Kang, “Quantitative transverse flow measurement using optical coherence tomography speckle decorrelation analysis,” Opt. Lett. 38, 805-807 (2013) Taryn E Travis, Matthew Mino, Lauren Moffatt, Neil Mauskar, Pejhman Ghassemi, Jessica Ramella-Roman, Marion H Jordan, Jeffrey W. Shupp, “Biphasic Presence of Fibrocytes in a Porcine Hypertrophic Scar Model,” Journal of Burn Care & Rehabilitation, 34:2, (2013) J.W. Shupp, L.T. Moffatt, T.A. Nguyen, J.C. Ramella-Roman, R. Hammamieh, R.J. Leto, D.Y. Jo, P.R. Randad, M. Jett, J.C. Jeng, and M.H. Jordan “Examination of Local and Systemic In vivo Responses to Electrical Injury Using an Electrical Burn Delivery System,” Journal of Burn Care & Research, 33 – 1 (2012) L. Luu, P. A. Roman, Scott A. Mathews, J.C. Ramella-Roman, “Microfluidics based phantoms of superficial vascular network,” Biomedical Optics Express, 3(6), 1350-1364, (2012) Thu T.A. Nguyen, Hanh N.D. Le, Minh Vo, Zhaoyang Wang, Long Luu, and Jessica C. Ramella-Roman, “Three-dimensional phantoms for curvature correction in spatial frequency domain imaging,” Biomedical Optics Express, 3(6), 1200-1214, (2012) Q. Wang, Du Le, J.C. Ramella-Roman and J. Pfefer, “Broadband UV-Vis optical property measurement in layered turbid media,” Biomedical Optics Express 3(6), 1226-1240, (2012) J. Hwang, J.C. Ramella-Roman, and R. Nordstrom, “Introduction: Feature Issue on Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices,” Biomedical Optics Express, 3(6), 1399-1403 (2012) Pejhman Ghassemi, Paul Lemaillet, Thomas A. Germer, Jeffrey W. Shupp, Suraj S. Venna, Marc E. Boisvert, Katherine E. Flanagan, Marion H. Jordan, and Jessica C. Ramella-Roman, “Out-of-plane Stokes imaging polarimeter for early skin cancer diagnosis,” J. Biomed. Opt. 17, 076014 (2012), DOI:10.1117/1.JBO.17.7.076014 Du V. N. Le; Quanzeng Wang; Jessica C. Ramella-Roman; T. Joshua Pfefer, “Monte Carlo modeling of light-tissue interactions in narrow band imaging,” J. Biomed. Opt. 18 (1), 010504 (2012); doi: 10.1117/1.JBO.18.1.010504 Nguyen, Thu T. A.; Ramella-Roman, Jessica C.; Moffatt, Lauren T.; Ortiz, Rachel T.; Jordan, Marion H.; Shupp, Jeffrey W., “Novel Application of a Spatial Frequency Domain Imaging System to Determine Signature Spectral Differences Between Infected and Noninfected Burn Wounds,” Journal of Burn Care & Research, 34 - 1 44–50 (2013) (2012 Burke/Yannas Bioengineering Award)