Li, Chenzhong - Florida International University - Department of Biomedical Engineering

个人简介

Prof. Chenzhong Li, the principal investigator of the nanobioengineering/bioelectronics lab, in the Biomedical Engineering Department at Florida International University (Miami). Dr. Li received his M.Sc and Ph.D from Kumamoto University in Japan . Dr. Li served as a post-doctoral research associate at the university of British Columbia and as professional research associate at the University of Saskatchewan and Adnavance Technologies, Inc. He worked at Nanobiotechnology/Biosensor Group of Biotechnology Research Institute, Canada National Research Council as Research Officer till 2006. He joined in FIU in 2006 and tenured in the Department of Biomedical Engineering and He is an affiliated faculty in the Department of Immunology at the College of Medicine. Dr. Li is an expert in nanobioengineering, bioelectronics and electrochemistry, specifically in the development of biomedical devices including biosensors and biofuel cells. Dr. Li’s research interests also include Biosensors, BioMEMS, Lab on Chip, Point Care of Testings, cell biology, biomarker and nanotoxicity measurements and electron transfer study of various biomolecules.

研究领域

1. Miniaturized Biosensors for Point of Care Testings My lab is developing several optical and electrical biosensing platforms coupling micro/nano materials, microfluidic technology, and nanoparticles for the detection of biomarkers for cancer, Alzheimer’s disease, and DNA oxidative damage. The novel approaches for biomarker detection developed in my laboratory could be applied to the diagnosis of chronic conditions (cancers, cardiac disease, autoimmune diseases), acute events (stroke, cardiac ischemia, head injury), or pathogen detection and toxin exposure assessments, all using a simple, rapid and sensitive device. 2. Whole Cell Analysis and Manipulations The main focus of this research is toward the development of whole cell based electronic biosensors for monitoring and modulating cellular behaviors at the single cell level or for a group of cells. We developed a chip based cell impedance sensing system capable of rapid assessment of nanotoxicity, neuronal mapping and electrical manipulation of cells. 3. Environmental Sensors for Biological Toxins and Other Chemical Pollution Assay This work focuses on the development of environmental biosensors for the detection of pathogenic bacteria cells, explosive compounds, radioactive and heavy metals and pesticide and phosphate contaminants. This work was done in collaboration with Pacific Northwest National Laboratory, Department of Chemistry (FIU), Everglades Foundation, and the Department of Chemistry at the University of Texas at El Paso. 4. Miniaturized Implantable Enzymatic Biofuel Cell for Sustainable Energy Supply Editorial Service: 2013 – Guest Editor, Special Issue on Neuron Biosensors, Journal of Neuroscience and Neuroengineering (American Scientific Publishers). 2014- Present – Editor, Journal of Sensors (Hindawi Publishing Corporation) 2012- Present – Associate Editor, Chemical Sensors (Simplex Academic Publishers) 2012- Present – Academic Editor, PLoS ONE 2011- Present – Associate Editor, Biosensors Journal (Ashdin Publishing) 2010- Present – Associate Editor, Applied Biochemistry and Biotechnology (Springer) 2009 – Guest Editor, Special Issue on Biomedical Engineering, American Journal of Biomedical Science (New World Publishing International, Inc NWPII)

近期论文

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R. Guduru, D. Carvajal, Y. Katsenovich, L. Lagos, D. McDaniel, C.-Z. Li, “Investigation of the Effect of Uranium on Microbial Surfaces using Atomic Force Microscopy”, WM2011 Conference Proceedings... 2015 A. Badr, D. M.M. AlSadek, M. P. Mathew, C.-Z. Li, L. B. Djansugurova, K. J. Yarema, H. Ahmed, Nutrient-deprived cancer cells preferentially use sialic acid to maintain cell surface glycosylation,... C.-Z. Li, R. Jung, Z-Z, Wu, A Special Issue on Frontiers in Neural Biosensing Technology, Journal of Neuroscience and Neurengineering,, American Scientific Publishers, 2013. E. Hondroulis, P. Shah, X.... Chenzhong Li, Chang Liu, “Surface Plasmon Resonance Based Sensing Devices and Methods for Real-Time Analysis of Analyte Secretion From Living Cells”; Provisional patent, 2013, US 14/198,814. USPTO...