Li, Yan - Florida Agricultural and Mechanical University - Department of Chemical and Biomedical Engineering

个人简介

Ph.D., Chemical Engineering, The Ohio State University, 2002 B.S., Chemical Engineering, Tsinghua University (Beijing, China), 1995 2009-2011, Principal Scientist, Group/Project Leader, Department of Process Sciences, Geron Corporation 2007-2009, Senior Scientist, Department of Process Sciences, Geron Corporation 2003-2006, Scientist II, Department of Product Development, Geron Corportation 2002-2003, Scientist, Department of Product Development, Geron Corporation

研究领域

Stem cell technology and engineering Tissue engineering and biomaterials Cell processing and bioprocessing

近期论文

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L Song, K Wang, Y Li*, Y Yang. Nanotopography promoted neuronal differentiation of human induced pluripotent stem cells. Colloids and Surfaces B: Biointerfaces. 2016, In Press. DOI: 10.1016/j.colsurfb.2016.08.041 Y Yan, J Bejoy, J Xia, J Guan, Y Zhou, Y Li*. Neural patterning of human induced pluripotent stem cells in 3-D cultures for studying biomolecule-directed differential cellular responses. Acta Biomaterialia. 2016, 42, 114-126. J Bejoy, L Song, Y Li*. Wnt-YAP interactions in the neural fate of human pluripotent stem cells and the implications for neural organoid formation. Organogenesis. 2016; 12: 1-15. [Invited] S Sart, Y Yan, Y Li, E Lochner, C Zeng, T Ma, Y Li*. Crosslinking of extracellular matrix scaffolds derived from pluripotent stem cell aggregates modulates neural differentiation. Acta Biomaterialia. 2016; 30: 222-232. Y Yan, L Martin, D Bosco, J Bundy, R Nowakowski, Q.-X. Amy Sang, Y Li*. Differential effects of acellular embryonic matrices on pluripotent stem cell expansion and neural differentiation. Biomaterials. 2015; 73: 231-242. J Xia, Z Wang, D Huang, Y Yan, Y Li, J Guan. Asymmetric biodegradable microdevices for cell-borne drug delivery. ACS Applied Materials & Interfaces. 2015; 7: 6293-6299. S Sart, Y Yan, Y Li. The microenvironment of embryoid bodies modulated the commitment to neural lineage post-cryopreservation. Tissue Engineering Part C: Methods. 2015; 21: 356-366. Y Yan, F Calixto Bejarano, S Sart, M Muroski, GF Strouse, S Grant, Y Li. Cryopreservation of embryonic stem cell-derived multicellular neural aggregates labeled with micron-sized particles of iron oxide for magnetic resonance imaging. Biotechnology Progress. 2015; 31: 510-521. S Sart, F Calixto Bejarano, MA Baird, Y Yan, JT Rosenberg, T Ma, S Grant, Y Li. Intracellular labeling of mouse embryonic stem cell-derived neural progenitor aggregates with micron-sized particles of iron oxide. Cytotherapy. 2015; 17: 98-111. Z Wang, J Xia, Y Yan, A-C Tsai, Y Li, T Ma, J Guan. Facile functionalization and assembly of live cells with microcontact printed polymeric biomaterials. Acta Biomaterialia. 2015; 11: 80-87. S Sart, L Song, Y Li*. Controlling redox status for stem cell survival, expansion and differentiation. Oxidative Medicine and Cellular Longevity. 2015; Article ID 105135: 1-14. [Invited] M Liu, Y Li, S-T Yang. Effects of naringin on the proliferation and osteogenic differentiation of human amniotic fluid derived stem cells. Journal of Tissue Engineering and Regenerative Medicine. 2014, In Press. DOI: 10.1002/term.1911. Y Li*, C Xu, T Ma. In vitro organogenesis from pluripotent stem cells (Views and Commentaries). Organogenesis. 2014; 10: 159-163. [Invited] S Sart, Y Liu, T Ma, Y Li. Microenvironment regulation of pluripotent stem cell-derived neural progenitor aggregates by human mesenchymal stem cell secretome. Tissue Engineering Part A 2014; 20: 2666-2679. S Sart, SN Agathos, Y Li. Process engineering of stem cell metabolism for large scale expansion and differentiation in bioreactors. Biochemical Engineering Journal 2014; 84: 74-82. S Sart, A-C Tsai, Y Li, T Ma. Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications. Tissue Engineering Part B Reviews 2014; 20: 365-380. M Liu, Y Li, S-T Yang. Curculigoside improves osteogenesis of human amniotic fluid derived stem cells. Stem Cells and Development 2014; 23:146-154. S Sart, T Ma, Y Li. Extracellular matrices decellularized from embryonic stem cells maintained their structure and signaling specificity. Tissue Engineering Part A 2014; 20: 54-66. S Sart, SN Agathos, Y Li. Engineering stem cell fate with biochemical and biomechanical properties of microcarriers. Biotechnology Progress 2013; 29: 1354-1366. Y Li, A Gautam, J Yang, L Qiu, Z Melkoumian, J Weber, L Telukuntla, R Srivastava, E Whiteley, R Brandenberger. Oligodendrocyte progenitor cell differentiation from human embryonic stem cells on vitronectin-derived synthetic peptide acrylate surface. Stem Cells and Development 2013; 22, 1497-1505. N Liu, Y Li, and S-T Yang. Microfibrous carriers for integrated expansion and neural differentiation of embryonic stem cells in suspension bioreactor. Biochemical Engineering Journal 2013; 75: 55-63. BM Mooney, NA Raof, Y Li, Y Xie. Convergent mechanisms in pluripotent stem cells and cancer: Implications for stem cell engineering. Biotechnology Journal 2013; 8: 408-419. S Sart, T Ma, Y Li. Cryopreservation of pluripotent stem cell aggregates in defined protein-free formulation. Biotechnology Progress 2013; 29: 143-153. Y Li, T Ma. Bioprocessing of cryopreservation for large scale banking of human pluripotent stem cells. BioResearch Open Access. 2012; 1: 205-214. C Xu, S Police, M Hassanipour, Y Li, Y Chen, C Priest, C O’Sullivan, MA Laflamme, W-Z Zhu, J Yang, K Delavan-Boorsma, A Davies, J Lebkowski and JD Gold. Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells. Regenerative Medicine. 2011; 6(1): 53-66.