个人简介
高建
职务: 副教授
专业: 药理学
Education/Working Experience
1994/09--1998/07 Anhui Chinese Medicine University Bachelor
2001/09--2004/07 Anhui Medical University Master
2006/09--2009/07 Anhui Medical University PhD
2009/11--2015/10 The First Hospital of Anhui Medical University AssociateChief Pharmacist
2015/11--Present The Second Hospital of Dalian Medical University ChiefPharmacist;Director of Division of Research and Development Department ; Associate Director of pharmaceutical department
Research Projects/Grants
1. Natural Science Foundation of China, 81473267, P62 regulates Keap1-Nrf2-ARE signaling pathway during PF, 2015/01-2018/12.
2. Natural Science Foundation of China, 81274172, Nrf2 regulates TGFβ-Smad signaling pathway in oxidative stress-induced PF and the mechanism of Total glucosides of Danggui–Buxue–Tang, 2013/01-2016/12.
Admission Plan/Requirements
Admission Plan:1-2 foreign postgraduate
Requirements: Decent English level;Healthy ;Honesty; Hard-Working
近期论文
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1. Total Glucosides of Danggui Buxue Tang Attenuate BLM-Induced Pulmonary Fibrosis via Regulating Oxidative Stress by Inhibiting NOX4. Oxidative Medicine and Cellular Longevity.(IF:4.492)
2. High-Mobility Group Box 1 Mediates Epithelial-to-Mesenchymal Transition in Pulmonary Fibrosis Involving Transforming Growth Factor-β1/Smad2/3 Signaling. Journal of pharmacology and experimental therapeutics.(IF:3.972)
3. Inositol-requiring protein 1-X-box-binding protein 1 pathway promotes epithelial-mesenchymal transition via mediating snail expression in pulmonary fibrosis. International journal of biochemistry & cell biology.(IF:3.905)
4. Total extract of Yupingfeng attenuates bleomycin-induced pulmonary fibrosis in rats. Phytomedicine.(IF:2.937)
5. Total glycosides of Yupingfeng protects against bleomycin-induced pulmonary fibrosis in rats associated withreduced high mobility group box1 activation and epithelial-mesenchymal transition. Inflamm Res.(IF:2.347)
6. Total Polysaccharide of Yupingfeng Protects against Bleomycin-Induced Pulmonary Fibrosis via Inhibiting TGF-ß1-Mediated Type I Collagen Abnormal Deposition in Rats. Journal of Pharmacy and Pharmacology.(IF:2.363)
7. Functions of galectin-3 and its role in fibrotic diseases. Journal of pharmacology and experimental therapeutics.(IF:3.972)
8. Emerging role of HMGB1 in fibrotic diseases. Journal of cellular and molecular medicine.(IF:4.938)
9. Total glucosides of Danggui– Buxue–Tang attenuates bleomycin-induced pulmonary fibrosis via inhibition of extracellular matrix remodeling. Journal of Pharmacy and Pharmacology.(IF:2.363)
10. Total glucosides of Danggui Buxue Tang ameliorates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-beta1/Smad pathway and altering the MMP2/TIMP1 ratio. Journal of Ethnopharmacology.(IF:3.055)
学术兼职
SeniorMember of ChinesePharmaceuticalAssociation
Standing Committee Member of Tonicpharmacology ofChinesePharmacologicalSociety
Standing Committee Member of PharmaceuticPreparationofChina Association of Chinese Medicine
Member of ChineseCrudeDrugProcessing ofChina Association of Chinese Medicine