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Narayan M, Kirouac L, Chaput D, Stevens S, Padmanabhan J, Jinwal U, K. Identification of Novel Cdc37 Interacting Proteins and Pathways in Human Alzheimer’s Disease Brain Tissue using Mass Spectrometry. Journal of Data Mining in Genomics & Proteomics. 7: 193, 2016.
Narayan M, Seeley K, W, Jinwal U, . ) Identification of Apo B48 and other novel biomarkers in amyotrophic lateral sclerosis patient fibroblasts. Biomarkers in Medicine. 10: 453-462, 2016.
Narayan M, Seeley K, W, Jinwal U, K. Data from SILAC-based quantitative analysis of lysates from mouse microglial cells treated with Withaferin A (WA). Data in Brief. 7: 747-750, 2016.
Klionsky D, J, …, , Jinwal U, K, …, , Zughaier S, M, et, al, . Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1 -222, 2016.
Young ZT Rauch JN Assimon VA Jinwal UK Ahn M Li X Dunyak BM Ahmad A Carlson GA Srinivasan SR Zuiderweg ER Dickey CA Gestwicki JE. Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy. Cell Chemical Biology. 23: 1-10, 2016.
Martin MD, Calcul L, Smith C, Jinwal UK, Fontaine SN, Darling A, Seeley K, Wojtas L, Narayan M, Gestwicki JE, Smith GR, Reitz AB, Baker BJ, Dickey CA. Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance. ACS chemical biology. 10(4) : 1099-109, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25588114
Fontaine SN, Rauch JN, Nordhues BA, Assimon VA, Stothert AR, Jinwal UK, Sabbagh JJ, Chang L, Stevens SM, Zuiderweg ER, Gestwicki JE, Dickey CA. Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement. The Journal of biological chemistry. 290(21) : 13115-27, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25864199
Narayan M, Zhang J, Braswell K, Gibson C, Zitnyar A, Lee DC, Varghese-Gupta S, Jinwal UK. Withaferin A regulates LRRK2 levels by interfering with the Hsp90-Cdc37 chaperone complex. Current aging science. 8: 259-65, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25989799
Narayan M, Peralta DA, Gibson C, Zitnyar A, Jinwal UK. An optimized InCell Western screening technique identifies hexachlorophene as a novel potent TDP43 targeting drug. Journal of biotechnology. 207: 34-8, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25987361
8, Narayan M, Peralta D, A, Gibson C, Zitnyar A, Jinwal U, . An optimized InCell Western screening technique identifies hexachlorophene as a novel potent TDP43 targeting drug. Journal of Biotechnology. 207: 34-38, 2015.
Narayan M, Seeley K, W, Jinwal U, . Identification and Characterization of Cellular Proteins Affected by Treatment with Withaferin A using a SILAC-based Proteomics Approach. Journal of Ethnopharmacology. 175: 86-92, 2015.
Jinwal U, K Grover A, Narayan M, Hirani A, Sutariya V, B. Preparation and Characterization of MKT-077 Nanoparticles for brain-targeted treatment of Alzheimer’s disease and other Tauopathies Pharmaceutical Nanotechnology. 2: 217-226, 2014.
Jinwal UK, Groshev A, Zhang J, Grover A, Sutariya VB. Preparation and characterization of methylene blue nanoparticles for Alzheimer's disease and other tauopathies. Current drug delivery. 11(4) : 541-50, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24237400
Braswell K, Dickey CA, Jinwal UK. A commentary on: Modulating molecular chaperones improves sensory fiber recovery and mitochondrial function in diabetic peripheral neuropathy. Experimental neurology. 241: 122-4, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23298520
Abisambra J, Jinwal UK, Miyata Y, Rogers J, Blair L, Li X, Seguin SP, Wang L, Jin Y, Bacon J, Brady S, Cockman M, Guidi C, Zhang J, Koren J, Young ZT, Atkins CA, Zhang B, Lawson LY, Weeber EJ, Brodsky JL, Gestwicki JE, Dickey CA. Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau. Biological psychiatry. 74(5) : 367-74, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23607970
Jinwal UK, Koren J, Dickey CA. Reconstructing the Hsp90/Tau Machine. Current enzyme inhibition. 9(1) : 41-45, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23798910
Abisambra JF, Jinwal UK, Blair LJ, O'Leary JC, Li Q, Brady S, Wang L, Guidi CE, Zhang B, Nordhues BA, Cockman M, Suntharalingham A, Li P, Jin Y, Atkins CA, Dickey CA. Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(22) : 9498-507, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23719816
Jinwal UK, Akoury E, Abisambra JF, O'Leary JC, Thompson AD, Blair LJ, Jin Y, Bacon J, Nordhues BA, Cockman M, Zhang J, Li P, Zhang B, Borysov S, Uversky VN, Biernat J, Mandelkow E, Gestwicki JE, Zweckstetter M, Dickey CA. Imbalance of Hsp70 family variants fosters tau accumulation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 27(4) : 1450-9, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23271055
Totten DC, Vuong M, Litvinova OV, Jinwal UK, Gulia-Nuss M, Harrell RA, Bene? H. Targeting gene expression to the female larval fat body of transgenic Aedes aegypti mosquitoes. Insect molecular biology. 22(1) : 18-30, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23241066
Miyata Y, Li X, Lee HF, Jinwal UK, Srinivasan SR, Seguin SP, Young ZT, Brodsky JL, Dickey CA, Sun D, Gestwicki JE. Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels. ACS chemical neuroscience. 4(6) : 930-9, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23472668
Abisambra, J.F., Jinwal, U.K., Suntharalingam, A., Arulselvam, K. Brady, S., Cockman, M.S., Jin, Y., Zhang, B., Dickey, C.A. DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau Journal of Molecular Biology. , 2012.
Koren, J. III., Miyata, Y., Kiray, J., O’Leary, J.C., Nguyen, L., Guo, J., Blair, L.J., Jinwal, U.K., Cheng, J.Q., Gestwicki, J.E., Dickey, C.A. Rhodacyanine derivatives selectively targets cancer cells and overcomes tamoxifen resistance PLoS ONE. , 2012.
Calcul, L., Zhang, B., Jinwal, U.K., Dickey, C.A., Baker, B.J. products are a rich source of tau-targeting drugs for Alzheimer’s disease Future Medicinal Chemistry. , 2012.
Jinwal, U.K., J.H., Abisambra, J.F., Zhang, J., Dharia, S., O’Leary, J.C., Patel, T., Braswell, K., Jani, T., Gestwicki, J.E., Dickey, C.A. Cdc37/ Hsp90 Complex disruption triggers an autophagic clearance cascade for TDP-43 The Journal of Biological Chemistry. , 2012.
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