个人简介
Education
Ph.D. in Biophysics, University of Virginia, Charlottesville, VA 07/2006 – 05/2010
Graduate Student, Department of Applied Physics, Rice University, Houston, TX 01/2005 – 06/2006
Ph.D. in Organic Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai, China 09/1998 – 01/2003
Bachelor in Chemistry, Nanjing University, Nanjing, China 09/1994 – 07/1998
Postgraduate Training
Department of Neurobiology, Yale University, New Haven, CT 05/2010 – 05/2012
Department of Chemistry, University of Illinois at Urbana and Champaign, Urbana, IL 01/2003 – 01/2005
Appointments
Associate Professor, Department of Pharmaceutical Sciences,College of Pharmacy, University of South Florida, Tampa, FL.2018-present
Adjunct Associate Professor, Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida,Tampa, FL.2018-present
Assistant Professor, Department of Pharmaceutical Sciences,College of Pharmacy, University of South Florida, Tampa, FL.2012-2018
Adjunct Assistant Professor, Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida,Tampa, FL.2012-2018
Moffitt Cancer Center Support Grant (CCSG) Collaborator Member, Moffitt Cancer Center, Tampa, FL.2013-2017
研究领域
Dr. Cheng is a computational biologist. He received systematic training in bioinformatics at Chinese Academy of Science, University of Illinois at Urbana Champaign, Rice University, University of Virginia and Yale University. His researches mainly focus on applications of bioinformatics methods for the identifications of drug-drug interactions (DDIs) and for drug repositioning by analyzing Big Data from public resources. He is also interested in computer-aided drug design. Dr. Cheng has published over 70 research papers in prestigious journals including Nature, Neuron, J. Am. Chem. Soc, and Scientific Reports. His work has been cited more than 3,200 times. Presently, Dr. Cheng is an editor board member of Journal of Proteomics and Bioinformatics, and the Open Bioinformatics Journal. Dr. Cheng has been serving as a peer reviewer for more than ten journals.
近期论文
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Carris, N. W., Tsalatsanis, A., Tipparaju, S. M., Cheng, F.,Magness, R. R., & Kumar, A."Metformin's impact on statin‐associated muscle symptoms: An analysis of ACCORD study data and research materials from the NHLBI Biologic Specimen and Data Repository Information Coordinating Center." Diabetes, Obesity and Metabolism (2018) March.6.36 /106
Hu Y, Fang Z, Yang Y, Rohlsen-Neal D, Cheng F*, Wang J*.Analyzing the genes related to nicotine addiction or schizophrenia via a pathway and network based approach.Scientific Reports. 2018 8(1):2894.4.847 / 69
Wang XL, Cheng F, Rohlsen D, Bi CW, Wang CY, Xu YQ, Wei SY, Ye QL, Yin TM, Ye N, Organellar genomes assembly methods and comparative analysis of horticultural plants.Horticulture Research, 2018, 5:33.6 / 3
Xiao WB*, Dai J, Wu HM, Zhang HM, Cheng F*, Effect of the meteorological factors on photovoltaic power forecast based on neural network, RSC Adv., 2017,7, 55846-558503.108 / 84
Xiao WB*, Nazario G, H.M. Wu HM, H.M. Zhang HM, Cheng F*,A Neural Network Based Computational Model to Predict the Output Power of Different Types of Photovoltaic Cells. Plos One, 2017, 12 (9): e0184561 3.394 / 181
Tur J, Sachin L. Badole1 Cheng F, Das A, Kukreja RC, Tipparaju SM: Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvb1.1 (AKR6A8) subunit of voltage-gated potassium channel. Mol Cell Biochem, 2017, 436:71–78 2.487 / 103
Luo YY, Xiong XY, Cheng F, Gong YC, Li ZL, Li YP, The targeting Properties of Folate-conjugate Pluronic F127/poly (lactic-co-glycolic) nanoparticles, International Journal of Biological Macromolecules, 2017, 105, 711-719 3.657 / 75
Carris NW, Cheng F, Kelly WN, “The Changing Cost to Prevent Diabetes: A Retrospective Analysis of the Diabetes Prevention Program”. Journal of the American Pharmacists Association, 2017, 57 (6), 717-722
Paullin T, Powell C, Menzie C, Hill R, Cheng F, Martyniuk CJ,Westerheide SD. Spheroid growth in ovarian cancer alters transcriptome responses for stress pathways and epigenetic responses. PLoS One 2017, 12 (8), e0182930 3.394 / 181
Brunquell J, Cheng F*, Westerheide SD*, HSF-1 is a Regulator of miRNA Expression in Caenorhabditis elegans Plos One,2017, 12 (8): e0183445 3.394 / 181
MohanKumar K, Namachivayam K, Cheng F, Jiang RH, FloresTorres J, Torres BA, Maheshwari A: Trinitrobenzene sulfonic acid-induced intestinal injury in neonatal mice activates transcriptional networks similar to those seen in human necrotizing enterocolitis. Pediatric Res 2017, 81(1-1):99-112.3.110 / 117
Niu NK, Wang Q, Shi, J, Zhang X, Geng G, Zhou SF, Thach, C,Cheng F, and Wang Z: Clinical and genomic responses to ultra-short course chemotherapy in spinal tuberculosis.Experimental and Therapeutic Medicine, 2017, 13: 1681-1688.1.367 / 18
Lu Y, Figler, B, Huang H, Tu YC, Wang J, Cheng, F*:Characterization of the Mechanism of Drug-drug Interactions from PubMed using MeSH Terms. PLoS One 2017, 12 (4),e0173548.3.394 / 181
Xiong XY, Pan XQ, Tao L, Cheng F, Li ZP, Gong YC, Li, YP:“Enhanced Effect of Folated Pluronic F87-PLA/TPGS Mixed Micelles on Targeted Delivery of Paclitaxel”, International Journal of Biological Macromolecules, 2017, 103:1011-1018 3.657 / 75
Brunquell J, Morris S, Lu Y, Cheng F, Westerheide SD: The genome-wide role of HSF-1 in the regulation of gene expression in Caenorhabditis elegans. BMC Genomics 2016,17:559.4.284 / 108
Olmos-Serrano JL, Kang HJ, Tyler WA, Silbereis JC, Cheng F,Zhu Y, Pletikos M, Jankovic-Rapan L, Cramer NP, Galdzicki Z et al: Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination. Neuron 2016, 89(6):1208-1222.15.832 / 372
Liu M, Fan R, Liu X, Cheng F*, Wang J*: Pathways and networks-based analysis of candidate genes associated with nicotine addiction. PLoS One 2015, 10(5): e0127438.3.394 / 181
Lu Y, Shen D, Pietsch M, Nagar C, Fadli Z, Huang H, Tu YC, Cheng F*: A novel algorithm for analyzing drug-drug interactions from MEDLINE literature. Sci Rep 2015, 5:17357.4.847 / 69
Xu Y, Hu B, Alnajm SS, Lu Y, Huang Y, Allen-Gipson D, Cheng F*: SEGEL: A Web Server for Visualization of Smoking Effects on Human Lung Gene Expression. PLoS One 2015,10(5):e0128326. 3.394 / 181
Gupta AR, Pirruccello M, Cheng F, Kang HJ, Fernandez TV,Baskin JM, Choi M, Liu L, Ercan-Sencicek AG, Murdoch JD et al:Rare deleterious mutations of the gene EFR3A in autism spectrum disorders. Mol Autism 2014, 5:31.5.663 / 23