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PHD, Medical Microbiology, Tianjin Medical University, 1996 MPH, Biostatistics and Epidemiology, Tianjin Medical University, 1993

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Lin D, Wu Q, Lin X, Borlongan CV, He ZX, Tan J, Cao C, Zhou SF. Brain-derived Neurotrophic Factor Signaling Pathway: Modulation by Acupuncture in Telomerase Knockout Mice. Alternative therapies in health and medicine. 21(6) : 36-46http://www.ncbi.nlm.nih.gov/pubmed/26567448 Song S, Kong X, Sava V, Cao C, Acosta S, Borlongan C, Sanchez-Ramos J. Transient Micro-needle Insertion into Hippocampus Triggers Neurogenesis and Decreases Amyloid Burden in a Mouse Model of Alzheimer's Disease. Cell transplantation. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/26892497 Lin L, Skakavac N, Lin X, Lin D, Borlongan MC, Borlongan CV, Cao C. Acupuncture-Induced Analgesia: The Role of Microglial Inhibition. Cell transplantation. 25(4) : 621-8, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26849399 Hao Y, Bai G, Wang J, Zhao L, Sutherland K, Cai J, Cao C. Identifiable biomarker and treatment development using HIV-1 long term non-progressor sera. BMC immunology. 16: 25, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25927639 Ugen KE, Lin X, Bai G, Liang Z, Cai J, Li K, Song S, Cao C, Sanchez-Ramos J. Evaluation of an α synuclein sensitized dendritic cell based vaccine in a transgenic mouse model of Parkinson disease. Human vaccines & immunotherapeutics. 11(4) : 922-30, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25714663 Shahaduzzaman M, Nash K, Hudson C, Sharif M, Grimmig B, Lin X, Bai G, Liu H, Ugen KE, Cao C, Bickford PC. Anti-human α-synuclein N-terminal peptide antibody protects against dopaminergic cell death and ameliorates behavioral deficits in an AAV-α-synuclein rat model of Parkinson's disease. PloS one. 10(2) : e0116841, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25658425 Chu L, Zhao H, Fang J, Li C, Liu Z, Cui R, Hu F, Zhang X, Chen Y, Han H, Cao C, Xu Q. The traditional Chinese medicinal formula BDL301 suppresses tumor growth by inhibiting STAT3 pathway and inducing apoptosis in colorectal cancer cells. DNA and cell biology. 34(3) : 178-88, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25607688 Zhang LF, Zhou ZW, Wang ZH, Du YH, He ZX, Cao C, Zhou SF. Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells. Drug design, development and therapy. 9: 241-72, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25565776 Cheng J, Zhou ZW, Sheng HP, He LJ, Fan XW, He ZX, Sun T, Zhang X, Zhao RJ, Gu L, Cao C, Zhou SF. An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides. Drug design, development and therapy. 9: 33-78, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25552899 Citron BA, Saykally JN, Cao C, Dennis JS, Runfeldt M, Arendash GW. Transcription factor Sp1 inhibition, memory, and cytokines in a mouse model of Alzheimer's disease. American journal of neurodegenerative disease. 4(2) : 40-8, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26807343 Cheng J, Lin X, Morgan D, Gordon M, Chen X, Wang ZH, Li HN, He LJ, Zhou SF, Cao C. Dendritic and Langerhans cells respond to Aβ peptides differently: implication for AD immunotherapy. Oncotarget. 6(34) : 35443-57, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26473448 Li Y, Wu H, Teng P, Bai G, Lin X, Zuo X, Cao C, Cai J. Helical Antimicrobial Sulfono-γ-AApeptides. Journal of medicinal chemistry. 58(11) : 4802-11, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26020456 Lin D, De La Pena I, Lin L, Zhou SF, Borlongan CV, Cao C. The neuroprotective role of acupuncture and activation of the BDNF signaling pathway. International journal of molecular sciences. 15(2) : 3234-52, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24566146 Padhee S, Smith C, Wu H, Li Y, Manoj N, Qiao Q, Khan Z, Cao C, Yin H, Cai J. The development of antimicrobial a-AApeptides that suppress proinflammatory immune responses. Chembiochem : a European journal of chemical biology. 15(5) : 688-94, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24677440 Cao C, Li Y, Liu H, Bai G, Mayl J, Lin X, Sutherland K, Nabar N, Cai J. The potential therapeutic effects of THC on Alzheimer's disease. Journal of Alzheimer's disease : JAD. 42(3) : 973-84, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25024327 Li Y, Smith C, Wu H, Teng P, Shi Y, Padhee S, Jones T, Nguyen AM, Cao C, Yin H, Cai J. Short antimicrobial lipo-α/γ-AA hybrid peptides. Chembiochem : a European journal of chemical biology. 15(15) : 2275-80, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25169879 Lin X, Bai G, Lin L, Wu H, Cai J, Ugen KE, Cao C. Vaccination induced changes in pro-inflammatory cytokine levels as an early putative biomarker for cognitive improvement in a transgenic mouse model for Alzheimer disease. Human vaccines & immunotherapeutics. 10(7) : 2024-31, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25424812 Wu H, Li Y, Bai G, Niu Y, Qiao Q, Tipton JD, Cao C, Cai J. γ-AApeptide-based small-molecule ligands that inhibit Aβ aggregation. Chemical communications (Cambridge, England). 50(40) : 5206-8, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24158240 Li Y, Smith C, Wu H, Padhee S, Manoj N, Cardiello J, Qiao Q, Cao C, Yin H, Cai J. Lipidated cyclic γ-AApeptides display both antimicrobial and anti-inflammatory activity. ACS chemical biology. 9(1) : 211-7, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24144063 Selenica ML, Alvarez JA, Nash KR, Lee DC, Cao C, Lin X, Reid P, Mouton PR, Morgan D, Gordon MN. Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain. Journal of neuroinflammation. 10: 86, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23866683 Niu Y, Wu H, Li Y, Hu Y, Padhee S, Li Q, Cao C, Cai J. AApeptides as a new class of antimicrobial agents. Organic & biomolecular chemistry. 11(26) : 4283-90, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23722277 Song S, Song S, Cao C, Lin X, Li K, Sava V, Sanchez-Ramos J. Hippocampal neurogenesis and the brain repair response to brief stereotaxic insertion of a microneedle. Stem cells international. 2013: 205878, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23554817 Nabar NR, Yuan F, Lin X, Wang L, Bai G, Mayl J, Li Y, Zhou SF, Wang J, Cai J, Cao C. Cell therapy: a safe and efficacious therapeutic treatment for Alzheimer's disease in APP+PS1 mice. PloS one. 7(12) : e49468, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23226497 Dragicevic N, Delic V, Cao C, Copes N, Lin X, Mamcarz M, Wang L, Arendash GW, Bradshaw PC. Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in Alzheimer's mice and cells. Neuropharmacology. 63(8) : 1368-79, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22959965 Hu Y, Amin MN, Padhee S, Wang RE, Qiao Q, Bai G, Li Y, Mathew A, Cao C, Cai J. Lipidated peptidomimetics with improved antimicrobial activity. ACS medicinal chemistry letters. 3(8) : 683-6, 2012. http://www.ncbi.nlm.nih.gov/pubmed/24900530

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