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个人简介

Nathan D. Gallant is an Assistant Professor in the Department of Mechanical Engineering at the University of South Florida. Professor Gallant joined the USF faculty in August 2008 following a National Research Council postdoctoral fellowship at the National Institute of Standards and Technology in the Polymers Division. He graduated with a B.S. degree in Mechanical Engineering and a Cooperative Education Certificate from the Georgia Institute of Technology in 1999. He went on to earn M.S. and Ph.D. degrees in Mechanical Engineering at the Georgia Institute of Technology in 2003 and 2004, respectively, working in the lab of Andres J. Garcia. Professor Gallant is an NSF CAREER award recipient for his work developing combinatorial biomaterials for mechanobiology.

研究领域

Materials, Tissue Engineering, Mechanotransduction

近期论文

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Elineni, K.K. and Gallant, N.D. Microtubules Mechanically Regulate Cell Adhesion Strengthening Via Cell Shape. Cellular and Molecular Bioengineering 7(1):136-144 (2014). Onen, O., Ahmad, A.A., Guldiken, R., and Gallant, N.D. Surface modification of acoustic wave biosensors for enhanced specificity. Sensors 12(9):12317-12328 (2012). Guldiken, R., Jo, M.C., Gallant, N.D., Demirci, U., and Zhe, J. Sheathless size-based acoustic particle separation. Sensors 12(1):905-922 (2012). Elineni, K.K. and Gallant, N.D. Regulation of cell adhesion strength by peripheral focal adhesion distribution. Biophysical Journal 101(12):2903-2911 (2011). Moore, N.M., Lin, N.J., Gallant, N.D., and Becker, M.L. Synergistic proliferation and osteogenic differentiation activity of human bone marrow stromal cells on BMP-2 derived and RGD peptide concentration gradients. Acta Biomaterialia 7(5):2091-2100 (2011). Acharya, A.P., Dolgova, N.V., Moore, N.M., Xia, C.Q., Clare-Salzler, M.J., Becker, M.L., Gallant N.D., and Keselowsky, B.G. The modulation of dendritic cell integrin binding and activation by RGD peptide density gradient substrates. Biomaterials 31(29):7444-7454 (2010). Moore, N.M., Lin, N.J., Gallant, N.D., and Becker, M.L. The use of immobilized osteogenic growth peptide on gradient substrates synthesized via click chemistry to enhance MC3T3-E1 osteoblast proliferation. Biomaterials 31(7):1604-1611 (2010). Dumbauld, D.W., Shin, H., Gallant, N.D., Michael, K.E., Radhakrishna, H., and Garcia, A.J. Contractility modulates adhesive force via focal adhesion kinase and assembly of vinculin-containing focal adhesions. Journal of Cellular Physiology 223(3):746-756 (2010). Jakupciak, J.P., Gallant, N.D., Becker, M.L., Tona, A., and Atha, D.H. Improved methods and standards for telomerase detection: Quantitative histopathology using antibody staining. Biotechnic and Histochemistry 84:195-206 (2009). Chen, R.I., Gallant, N.D., Smith, J.R., Kipper, M.J., and Simon Jr., C.G. Time-dependent effects of pre-aging polymer films in cell culture medium on cell adhesion and spreading. Journal of Materials Science Materials in Medicine 19:1757-1766 (2008). Becker, M.L., Fagan, J.A., Gallant, N.D., Bauer, B.J., Bajpai, V., Hobbie, E.K., Lacerda, S.H., Migler, K., and Jakupciak, J.P. Length dependent uptake of DNA-wrapped single walled carbon nanotubes. Advanced Materials 19(7):939-945 (2007). Gallant, N.D., Lavery, K.A., Amis, E.J., and Becker, M.L. Universal gradient substrates for “click” biofunctionalization. Advanced Materials 19(7):965-969 (2007). Gallant, N.D., Charest, J.L., King, W.P., and García, A.J. Micro- and nano-patterned substrates to manipulate cell adhesion. Journal of Nanoscience and Nanotechnology 7(3):803-807 (2007). Gallant, N.D. and García, A.J. Model of integrin-mediated cell adhesion strengthening. Journal of Biomechanics 40(6):1301-1309 (2007). Bailey, L.O., Becker, M.L., Stephens, J.S., Gallant, N.D., Mahoney, C.M., Washburn, N.R., Rege, A., Kohn, J., and Amis, E.J. Cellular response to phase-separated blends of tyrosine-derived polycarbonates. Journal of Biomedical Materials Research, Part A 76(3):491-502 (2006). Gallant, N.D., Michael, K.E., and García, A.J. Cell adhesion strengthening: Contributions of adhesive area, integrin binding and focal adhesion assembly. Molecular Biology of the Cell 16:4329-4340 (2005). García, A.J. and Gallant, N.D. “Stick and Grip”: Measurement systems and quantitative analyses of integrin-mediated cell adhesion strength. Cell Biochemistry and Biophysics 39:61-74 (2003). Gallant, N.D., Capadona, J.R., Frazier, A.B., Collard, D.M., and García A.J. Micropatterned surfaces to engineer focal adhesions for analysis of cell adhesion strengthening. Langmuir 18(14):5579-5584 (2002).

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