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Modular Assembly of Primary Metabolic Building Blocks: A Chemical Language in C. elegans. Frank C. Schroeder, Chem. Biol. 2015, 22, 7-16. doi:10.1016/j.chembiol.2014.10.012
B. subtilis GS67 protects C. elegans from Gram-positive pathogens via fengycin-mediated microbial antagonism. Igor Iatsenko, Joshua J. Yim, Frank C. Schroeder, Ralf J. Sommer, Curr. Biol. 2014, 24, 2720-2727.
Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus. Philipp Wiemann, Beatrix E. Lechner, Joshua A. Baccile, Thomas A. Velk, Wen-Bing Yin, Jin Woo Bok, Suman Pakala, Liliana Losada, William C. Nierman, Frank C. Schroeder, Hubertus Haas, Nancy P. Keller. Front. Microbiol. 2014, 5, 530.
Chemosensation of Bacterial Secondary Metabolites Modulates Neuroendocrine Signaling and Behavior of C. elegans. Joshua D. Meisel, Oishika Panda, Parag Mahanti, Frank C. Schroeder, Dennis H. Kim. Cell 2014, 159, 267-280. doi:10.1016/j.cell.2014.09.011
Activation of a G protein-coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans. Olivier Zugasti, Neelanjan Bose, Barbara Squiban, J�r�me Belougne, C. L�opold Kurz, Frank C. Schroeder, Nathalie Pujol, Jonathan J. Ewbank. Nat. Immunol. 2014, 15, 833-838. doi:10.1016/j.cub.2014.05.045
Small molecule signaling: encoding biological information in chemical structures. Frank C. Schroeder. In "Pristionchus pacificus - A nematode model for comparative and evolutionary biology", edited by Ralf J. Sommer. Brill, Leiden, NL, 2014, in press.
Endogenous NHR ligands: metabolomics to the rescue. Axel Bethke, Frank C. Schroeder. Aging, 2014, 6, 522-523. Editorial
Natural variation in dauer pheromone production and sensing supports intraspecific competition in nematodes. . Neelanjan Bose, Jan M. Meyer, Joshua J. Yim, Melanie G. Mayer, Gabriel V. Markov, Akira Ogawa, Frank C. Schroeder, Ralf J. Sommer. Curr. Biol. 2014, 24, 1536-1541. doi:10.1016/j.cub.2014.05.045
A Photocleavable Masked Nuclear-Receptor Ligand Enables Temporal Control of C. elegans Development. Joshua C. Judkins, Parag Mahanti, Jacob B. Hoffman, Isaiah Yim, Adam Antebi, Frank C. Schroeder. Angew. Chem. Int. Ed., 2014, 53, 2110-2113. DOI:10.1002/anie.201307465
Males Shorten the Life Span of C. elegans Hermaphrodites via Secreted Compounds. Travis J. Maures, Lauren N. Booth, Berenice A. Benayoun, Yevgeniy Izrayelit, Frank C. Schroeder, Anne Brunet. Science, 2014, 343, 541-544. DOI:10.1126/science.1244160
Comparative Metabolomics Reveals Endogenous Ligands of DAF-12, a Nuclear Hormone Receptor, Regulating C. elegans Development and Lifespan. Parag Mahanti, Neelanjan Bose. Axel Bethke, Joshua C. Judkins, Joshua Wollam, Kathleen J. Dumas, Anna M. Zimmerman, Sydney L. Campbell, Patrick J. Hu, Adam Antebi, Frank C. Schroeder. Cell Metab., 2014, 19, 73-83. DOI:10.1016/j.cmet.2013.11.024
Density dependence in Caenorhabditis larval starvation. Alexander B. Artyukhin, Frank C. Schroeder, Leon Avery.Scientific Reports, 2013, 19, 73-83.DOI:10.1016/j.cmet.2013.11.024
Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans. Cassandra Coburn, Erik Allman, Parag Mahanti, Alexandre Benedetto, Filipe Cabreiro, Zachary Pincus, Filip Matthijssens, Caroline Araiz, Abraham Mandel, Manolis Vlachos, Sally-Anne Edwards, Grahame Fischer, Alexander Davidson, Rosina E. Pryor, Ailsa Stevens, Frank J. Slack, Nektarios Tavernarakis, Bart P. Braeckman, Frank C. Schroeder, Keith Nehrke, David Gems. PLoS Biol., 2013, 11, e1001613. DOI:10.1371/journal.pbio.1001613
Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans. Alexander B. Artyukhin, Joshua J. Yim, Jagan Srinivasan, Neelanjan Bose, Stephan H. von Reuss, Yeara Jo, James M. Jordan, L. Ryan Bough, Micheong Cheong, Paul W. Sternberg, Leon Avery, Frank C. Schroeder. J. Biol. Chem., 2013, 288, 18778-18783. DOI:10.1074/jbc.C113.477000
Chemical defense of an Asian snake reflects local availability of toxic prey and hatchling diet. Deborah A. Hutchinson, Alan Savitzky, Gordon M. Burghardt, C. Nguyen, Jerrold Meinwald, Frank C. Schroeder, Akira Mori. J. Zool., 2013, 289, 270-278. DOI:10.1111/jzo.12004
Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARγ) agonist with potent glucose-lowering properties. Christopher Weidner, S.J. Wowro, Freiwald A, Ken Kawamoto, A. Witzke, M. Kliem, K. Siems, L. Müller-Kuhrt, Frank C. Schroeder, Sascha Sauer. Diabetologia, 2013, 56, 1802-1812. DOI 10.1007/s00125-013-2920-2
Protein sets define disease states and predict in vivo effects of drug treatment. David Meierhofer, Christopher Weidner, Ludger Hartmann, Johannes A. Mayr, Chung-Ting Han, Frank C. Schroeder, Sascha Sauer. Mol. Cell. Proteomics, 2013, 7, 1965-1979. DOI:10.1074/mcp.M112.025031
Pheremone sensing regulate Caenorhabditis elegans lifepsan and stress resistance via the deacetylase SIR-2.1. Andreas H. Ludewig, Yevgeniy Izrayelit, Donha Park, Rabia U. Malik, Anna Zimmerman, Parag Mahanti, Bennett W. Fox, Axel Bethke, Frank Doering, Donald L. Riddle, Frank C. Schroeder. Proc. Natl. Acad. Sci. USA, 2013, 110, 5522-5527. DOI:10.1073/pnas.1214467110
A Nonribosomal Peptide Synthetase-Derived Iron(III) Complex from the Pathogenic Fungus Aspergillus fumigatus. Wen-Bing Yin, Joshua A. Baccile, Jin Woo Bok, Yiming Chen, Nancy P. Keller, Frank C. Schroeder.J. Am. Chem. Soc., 2013, 135, 2064-2067. DOI:10.1021/ja311145n
A Family of Indoles Regulate Virulence and Shiga Toxin Production in Pathogenic E. coli. Bettina Bommarius, Akwasi Anyanful, Yevgeniy Izrayelit, Shantanu Bhatt, Emily Cartwright, Wei Wang, Alyson I. Swimm, Guy M. Benian, Frank C. Schroeder, Daniel Kalman.PLoS ONE, 2013, 8, e54456. DOI:10.1371/journal.pone.0054456