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个人简介

Dr. Christine E. Schnitzler earned a bachelor’s degree in Environmental Science from Northwestern University. She then earned her master’s degree in Marine Science from Moss Landing Marine Labs of California State University-Monterey Bay. She earned her doctorate in Zoology from Oregon State University. She was a postdoctoral fellow and research fellow at the National Human Genome Research Institute of the National Institutes of Health.

研究领域

Evolutionary, comparative, and functional genomics; stem cells and regeneration

近期论文

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T?r?k, A, Schiffer, PH, Schnitzler, CE, Ford, K, Mullikin, JC, Baxevanis, AD, Bacic, A, Frank, U, Gornik, SG. 2016. The cnidarian Hydractinia echinata employs canonical and highly adapted histones to pack its DNA. Epigenetics & Chromatin 9:36. PMCID: PMC5011920 Francis, WR, Christianson, LM, Powers, ML, Schnitzler, CE, Haddock, SHD. 2016. Non-excitable fluorescent protein orthologs found in ctenophores. BMC Evolutionary Biology 16:167. PMCID: PMC4997694. Ryan, JF, Schnitzler, CE, Tamm, SL. 2016. Meeting report of Ctenopalooza: the first international meeting of ctenophorologists. EvoDevo 7:19. Presnell, JS, Schnitzler, CE, Browne, WE. 2015. KLF/SP transcription factor family evolution: expansion, diversification, and innovation in eukaryotes. Genome Biology and Evolution 7:2289-2309. PMID: 26232396. Pope, WH, Bowman, CA, Russell, DA, Jacobs-Sera, D, Asai, DJ, Cresawn, SG, Jacobs, WR Jr, Hendrix, RW, Lawrence, JG, Hatfull, GF, Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science, Phage Hunters Integrating Research and Education, Mycobacterial Genetics Course. 2015. Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity. eLife 4:e06416. PMID: 25919952. [I was part of the Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science group.] Maxwell, EK, Schnitzler, CE, Havlak, P, Putnam, NH, Nguyen, AD, Moreland, RT, Baxevanis, AD. 2014. Evolutionary profiling reveals the heterogeneous origins of classes of human disease genes: implications for modeling disease genetics in animals. BMC Evolutionary Biology 14:212. PMID: 25281000. Schnitzler, CE, Simmons DK, Pang, K, Martindale, MQ, Baxevanis, AD. 2014. Expression of multiple Sox genes through embryonic development in the ctenophore Mnemiopsis leidyi is spatially restricted to zones of cell proliferation. EvoDevo 5:15. PMID: 24834317. Moreland, RT, Nguyen, AD, Ryan, JF, Schnitzler, CE, Koch, BJ*, Siewert, K*, Wolfsberg, TG, Baxevanis, A.D. 2014. A customized Web portal for the genome of the ctenophore Mnemiopsis leidyi. BMC Genomics 15:316. PMID: 24773765. Ryan, JF, Pang, K, Schnitzler, CE, Nguyen, A-D, Moreland, RT, Simmons, DK, Koch, BJ*, Francis, WR, Havlak, P, NISC Comparative Sequencing Program, Smith, SA, Putnam, NH, Haddock, SHD, Dunn, CW, Wolfsberg, TG, Mullikin, JC, Martindale, MQ, Baxevanis, AD. 2013. The genome of the ctenophore Mnemiopsis leidyi and its implications for cell type evolution. Science 342:1242592. PMCID: PMC3920664. Schnitzler, CE, Pang, K, Powers, M, Reitzel, AM, Ryan, JF, Simmons, D, Tada, T, Park, M, Gupta, J, Brooks, SY, Blakesley, RW, Yokoyama, S, Haddock, SHD, Martindale, MQ, Baxevanis, AD. 2012. Genomic organization, evolution, and expression of photoprotein and opsin genes in Mnemiopsis leidyi: a new view of ctenophore photocytes. BMC Biology 10:107. PMCID: PMC3570280. Maxwell, EK, Ryan, JF, Schnitzler, CE, Browne, WE, Baxevanis, AD. 2012. MicroRNAs and microRNA processing machinery are absent in the genome of the ctenophore Mnemiopsis leidyi. BMC Genomics 13:714. PMCID: PMC3563456. Detournay, O=, Schnitzler CE=, Poole, A, Weis VM. 2012. Regulation of cnidarian-dinoflagellate mutualisms: Evidence that activation of a host TGFb innate immune pathway promotes tolerance of the symbiont. Developmental and Comparative Immunology 38:525-537. =Co-first author. PMID: 23010490. Schnitzler, CE, Hollingsworth, LL, Krupp, DA, Weis, VM. 2012. Elevated temperature impairs onset of symbiosis and reduces survivorship in larvae of the Hawaiian coral, Fungia scutaria. Marine Biology 159:633-642. Pope, WH, Jacobs-Sera D, Russell DA, Peebles CL, Al-Atrache Z…Schnitzler, CE…et al. (192 authors) 2011. Expanding the diversity of mycobacteriophages: Insights into genome architecture and evolution. PLoS ONE 6(1):e16329. PMCID: PMC3029335. Schnitzler, CE, Weis, VM. 2010. Coral larvae exhibit few measurable transcriptional changes during the onset of coral-dinoflagellate endosymbiosis. Marine Genomics 3:107-116. PMID: 21798204. Richier, S, Rodriguez-Lanetty, M, Schnitzler, CE, Weis, VM. 2008. Response of the symbiotic cnidarian Anthopleura elegantissima transcriptome to temperature and UV increase. Comparative Biochemistry and Physiology D: Genomics and Proteomics 3:283-289. PMID: 20494848. Schnitzler, CE, Keenan, RJ, McCord, R, Matysik, A, Christianson, LM, Haddock, SHD. 2008. Spectral diversity of fluorescent proteins from the anthozoan Corynactis californica. Marine Biotechnology 10:328-342. Cover photo. PMID: 18330643. Dunn, SR, Schnitzler, CE, Weis, VM. 2007. Apoptosis and autophagy as mechanisms of dinoflagellate symbiont release during cnidarian bleaching: every which way you lose. Proceedings of the Royal Society of London Series B. 274:3079-3085. PMCID: PMC2293937. Haddock, SHD, Dunn, CW, Pugh, PR, Schnitzler, CE. 2005. Use of bioluminescent and red-fluorescent lures in deep-sea fish-eating siphonophores. Science 309:263. PMID: 16002609. Farzan, M, Chung, S, Li, W, Vasilieva, N, Wright, P, Schnitzler, CE, Marchione, RJ, Gerard, C, Gerard, NP, Sodroski, J, Choe, H. 2002. Tyrosine-sulfated peptides functionally reconstitute a CCR5 variant lacking a critical amino-terminal region. Journal of Biological Chemistry 277(43):40397-40402. PMID: 12183462. Farzan, M, Schnitzler, CE, Vasilieva, N, Leung, D, Kuhn, J, Gerard, C, Gerard, N, Choe, H. 2001. Sulfated tyrosines contribute to the formation of the C5a docking site of the human C5a anaphylatoxin receptor. Journal of Experimental Medicine 193(9):1059-66. PMCID: PMC2193433. Farzan, M, Vasilieva, N, Schnitzler, CE, Chung, S, Robinson, J, Gerard, NP, Gerard, C, Choe, H, Sodroski, J. 2000. A tyrosine-sulfated peptide based on the N-terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and Inhibits HIV-1 entry. Journal of Biogical Chemistry 275 (43):33516-33521. PMID: 10938094.

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