Allen, Josephine B. - University of Florida - Department of Materials Science & Engineering

个人简介

EMPLOYMENT 2010-Present University of Florida Materials Science and Engineering Assistant Professor ACADEMIC BACKGROUND 2009-2010 Northwestern University, Evanston, IL Biomedical Engineering Department Post-doctoral Associate 2002-2009 Northwestern University, Evanston, IL The Interdepartmental Biological Sciences (IBiS) Program Ph.D. degree received 5/2009 2000-2002 California State University Northridge, Northridge, CA Masters of Science in Cell and Molecular Biology (with Distinction) 1999-2000 California State University Northridge, Northridge, CA Bachelor of Arts in Biology 1991-1995 Howard University Washington, DC RESEARCH EXPERIENCE 2010-Present University of Florida – Principal Investigator Research Interest: Biomaterials, Cell-material interaction, Cardiovascular disease, vascular and orthopedic tissue engineering, stem cell engineering. The Allen Research group conducts research on biomaterials, cell-material interactions, and stem cell differentiation. The focus of our work is on developing strategies to control adult stem cell differentiation for tissue engineering and regenerative medicine. The goal is to better understand the multiple physiological signals and interactions that elicit molecular events governing stem cell differentiation. These molecular events, include substrate properties, mechanical cues, soluble factors, alternative growth conditions, and cell-cell communication ultimately control stem cell fate and are the target areas of our research. 2009-2010 Northwestern University – Post-doctoral Associate Advanced Nanocomposites for Bone Regeneration Advisor: Dr. Guillermo Ameer The overall objective of the work is to develop and characterize novel drug-eluting biodegradable nanocomposites that can guide or mediate new bone formation.

研究领域

Stem Cell Engineering; Directed Stem Cell differentiation, Cell Materials Interactions; Tissue Engineering; Regenerative Medicine

近期论文

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V Ramaswamy, A Goins, JB Allen. Altered Functions of Human Blood Derived Vascular Endothelial Cells by Simulated Microgravity. Gravitational and Space Research – In Press I. Berglund, E Dirr, V Ramaswamy, JB Allen, K. Allen, MV Manuel. The effect of Mg-Ca-Sr alloy degradation products on human mesenchymal stem cells. Journal of Biomedical Materials Research – Under Review Ramaswamy V, Dirr E., JB Allen. The Effect of Simulated Microgravity on Differentiation of Porcine Blood-Derived Vascular Stem Cells. Stem Cells and Development 2016 Feb 15;25(4): 329-36. I. Berglund, B. Jacobs, K. Allen, S. Kim, A Pozzi, JB Allen, M. Manuel. Peri-implant tissue response and degredation performance of Mg-1.0Ca-0.5Sr alloy in rat tibia. Materials Science and Engineering C. 2016 Vol 62: 79-85. V. Ramaswamy A Monsalve, L. Sautina, M. Segal, J. Dobson, JB Allen. DNA Aptamer Assembly as a Vascular Endothelial Growth Factor Receptor Agonist. Nucleic Acid Therapeutics 2015 Oct; 25(5):227-34. K. Baler, J.P. Ball, Z. Cankova, R. Hoshi, G. Ameer, JB Allen. Advanced nanocomposites for bone regeneration. Biomaterials Science. 2014 Vol 2 (10):1355-1366. H.S. Brar, I.S. Berglund, JB Allen, M Manuel. The role of surface oxidation on the degradation behavior of biodegradable Mg-RE (Gd, Y, Sc) alloys for resorbable implants. Materials Science and Engineering C 2014 Jul 1;40:407-417 J.P. Ball, B.A. Mound, A. Monsalve, J.C. Nino, JB Allen. Biocompatibility evaluation of porous Ceria foams for orthopedic tissue engineering. Journal of Biomedical Materials Research – Part A March 2014 Vol 103 (1): 8-15. J. Ball, B.A. Mound, J. Nino, JB Allen. Biocompatibility evaluation of Barium Titanate Foamed Ceramic Structures for Orthopedic Applications. Journal of Biomedical Materials Research – Part A 2014 Jul; 102(7): 2089-2095. H. S. Brar, J.P. Ball, I.S. Berglund, JB Allen, M.V. Manuel. A study of biodegradable Mg-3Sc-3Y alloy and the effect of surface passivation on in-vitro degradation. Acta Biomaterialia 2013 Feb; 9(2):5331-40 R. Hoshi, R. Van Lith, M. Jen, JB Allen, K. Lapidos, G. Ameer. Improving the blood and vascular cell compatibility of vascular grafts. Biomaterials 2013 Jan; 34(1):30-41 JB Allen, S. Khan, K. Lapidos, G. Ameer. Toward engineering a human neoendothelium with circulating progenitor cells. 2010 Stem Cells, vol 28, issue 2, 318-328. JB Allen, S. Khan, M.C. Serrano, G. Ameer. Characterization of porcine circulating progenitor cells on a novel biodegradable elastomer: towards a functional endothelium. Tissue Engineering, January 2008, vol 14, issue 1, 183-194. JB Allen*, D. Motlagh*, R. Hoshi, J. Yang, K. Lui, G. Ameer. Hemocompatibility evaluation of poly(diol citrate) in vitro for vascular tissue engineering. Journal of Biomedical Materials Research (JBMR-Part A). March 2007. Vol 82A, Issue 4, p907-916. (*) Authors contributed equally JB Allen, Y. Liu, Y.L. Kim, V. M. Turzhitsky, V. Backman, G. Ameer. Spectroscopic Translation of Cell-Material Interactions. Biomaterials 2007, (28) 162-174. J. Yang, D. Motlagh, JB Allen, A. Webb, MR Kibbe, O. Aalami, M. Kapadia, TJ Carroll, G Ameer. Modulating ePTFE vascular graft host response via citric acid-based biodegradable elastomers. Advance Material 2006, 18. 1493-1498 Y. Liu, JB Allen, Y. L. Kim, V. Turzhitsky, G. Ameer, V. Backman. Light Scattering "Fingerprinting" for Characterization of Smooth Muscle Cell Proliferation, Proceedings of SPIE, vol. 5319, BiOS 2004, Photonics West, San Jose, CA, January 24-29, 2004.