Wang, Yanchang - Florida State University - Department of Biomedical Sciences

个人简介

Ph.D., University of Virginia, Charlottesville, Va., 1993 - 1997 Postdoctoral fellow, HHMI, Baylor College of Medicine, Houston, Texas, 1997 - 2002

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Fengzhi, J., Hong, L., Ping, L., Hong-Guo, Y., & Wang, Y. (2012). Loss of function of the Cik1/Kar3 motor complex results in chromosomes with syntelic attachment that are sensed by the tension checkpoint. PLoS Genetics, 8, e1002492. Liu, H., Jin, F., Liang, F., Tian, X., & Wang, Y. (2011). The Cik1/Kar3 Motor Complex Is Required for the Proper Kinetochore-Microtubule Interaction After Stressful DNA Replication. Genetics, 187(2), 397-U58. Wang, Y. (2010). A new layer of regulation is required to silence the DNA damage checkpoint. Cell Cycle, 9(18), 3642-3642. Baldwin, M. L., Julius, J. A., Tang, X., Wang, Y., & Bachant, J. (2009). The yeast SUMO isopeptidase Smt4/Ulp2 and the polo kinase Cdc5 act in an opposing fashion to regulate sumoylation in mitosis and cohesion at centromeres. Cell Cycle, 8(20), 3406-3419. Liang, F., Jin, F., Liu, H., & Wang, Y. (2009). The Molecular Function of the Yeast Polo-like Kinase Cdc5 in Cdc14 Release during Early Anaphase. Mol Biol Cell, 20(16), 3671-3679. Zhang, J., Li, Y., Guo, L., Cao, R., Zhao, P., Jiang, W., Ma, Q., Yi, H., Li, Z., Jiang, J., Wu, J., Wang, Y., & Si, S. (2009). DH166, a beta-carboline derivative, inhibits the kinase activity of PLK1. Cancer Biol Ther, 8(24), 2374-2383. Fu, Da-Hua, Jiang, W., Zheng, Jian-Ting, Zhao, Gui-Yu, Li, Y., Yi, H., Li, Zhuo-Rong, Jiang, Jian-Dong, Yang, Ke-Qian, Wang, Y., & Si, Shu-Yi. (2008). Jadomycin B, an Aurora-B kinase inhibitor discovered through virtual screening. Mol Cancer Ther, 7(8), 2386-2393. Hong Liu, Fengshan Liang, Fengzhi Jin and Yanchang Wang. (2008) The coordination of centromere replication, spindle formation and kinetochore-microtubule interaction in budding yeast. PLoS Genetics. 4:e1000262. Epub 2008 Nov 21. Fengzhi Jin, Hong Liu, Fengshan Liang, Raed Rizkallah, Myra M. Hurt and Yanchang Wang (2008) Temporal control of the dephosphorylation of Cdk substrates by mitotic exit pathways in budding yeast. Proc Natl Acad Sci U S A. 105:16177-82 Fengshan Liang and Yanchang Wang (2007) DNA damage checkpoints inhibit mitotic exit by two different pathways. Molecular and Cellular Biology 14:5067-5078 Yan Li, Fengshan Liang, Wei Jiang, Fusheng Yu, Rihui Cao, Qinghe Ma, Xiuyong Dai, Jiandong Jiang, Yanchang Wang*, and Shuyi Si* (2007) DH334, a Beta-carboline anti-cancer drug, inhibits the CDK activity of budding yeast. Cancer Biology and Therapy 6(8) [Epub ahead of print] *co-corresponding author Tang X. and Wang Y. (2006) Pds1/Esp1 dependent and independent sister chromatid separation in mutants defective for protein phosphatase 2A. Proc Natl Acad Sci U S A. 103:16290-16295 Liu H. and Wang Y. (2006) The Function and Regulation of Budding Yeast Swe1 in Response to Interrupted DNA Synthesis. Mol Biol Cell. 17:2746-56 (Epub Mar. 2006) Wang Y. and Ng T. (2006) Phosphatase 2A negatively regulates mitotic exit in Saccharomyces cerevisiae. Mol. Biol Cell 17(1) 80-89 (Epub Aug. 2005) Wang Y, Shirogane T, Liu D, Harper JW, Elledge SJ. (2003) Exit from exit: resetting the cell cycle through Amn1 inhibition of G-protein signaling. Cell 112 (5):697-709 Hu F*, Wang Y*, Liu D, Li Y, Qin J, Elledge SJ. (2001) Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints. Cell 107(5):655-65. (*equal contributor) Wang Y*, Hu F*, Elledge SJ. (2000) The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit. Curr Biol. 2000 10(21):1379-82. (* equal contributor) Wang Y, Burke DJ. (1997) Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae. Mol Cell Biol. 17:620-6. Wang Y, Burke DJ. (1995) Checkpoint genes required to delay cell division in response to nocodazole respond to impaired kinetochore function in the yeast Saccharomyces cerevisiae. Mol Cell Biol 15:6838-44