Stefanovic, Branko - Florida State University - Department of Biomedical Sciences

个人简介

B.S., Medical Biochemistry, University of Zagreb, Croatia, 1978 Ph.D., Molecular Biophysics, Florida State University, Tallahassee, Fla., 1991 Postdoctoral Fellow, Dept. of Developmental Biology, University of Bern, Bern, Switzerland, 1992-1994

近期论文

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Zhang Y, Stefanovic B. Akt mediated phosphorylation of LARP6: critical step on biosynthesis of type I collagen. Sci Rep. 2016 Mar 2;6:22597 Stefanovic L, Longo L, Zhang Y, Stefanovic B. Characterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs: implications for synthesis of type I collagen. RNA Biol. 2014;11(11):1386-401. Seet LF, Toh LZ, Finger SN, Chu SW, Stefanovic B, Wong TT. Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis. J Mol Med (Berl). 2016 Mar;94(3):321-34. doi: 10.1007/s00109-015-1358-z. Epub 2015 Oct 27. Wang H., Stefanovic B. Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane. PLoS One. 2014 Oct 1;9(10):e108870. Manojlovic Z., Earwood R., Kato A., Stefanovic B., Kato Y. RFX7 is required for the formation of cilia in the neural tube. Mech. Dev. 2014, Feb. Blackstock C., Higashi Y., Sukhanov S., Shai SV., Stefanovic B., Tabony FM., Yoshida T., Delafontain P. Insulin-like growth factor 1 increases synthesis of collagen type I via induction of the mRNA binding protein LARP6 and binding to the 5’ stem-loop of col1A1 and col1A2 mRNA. J. Biol. Chem. 2014, Jan. Vukmirovic M, Manojlovic Z, Stefanovic B. Serine-threonine kinase receptor associated protein (STRAP) regulates translation of type I collagen mRNAs. Mol Cell Biol. 2013 Oct; 33 (19):3896-3906. Manojlovic Z, Blackmon J, Stefanovic B. Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis. PLoS One. 2013 Jun 3;8(6):e65897. Manojlovic, Z., & Stefanovic, B. (2012). A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs. RNA, 18(2), 321-34. Challa, A., & Stefanovic, B. (2011). A novel role of vementin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol, 31(18), 3773-89. Challa, A. A., & Stefanovic, B. (2011). A novel role of vimentin filaments; binding and stabilization of collagen mRNAs. Mol Cell Biol, 31(18), 3773-89. Fritz, D., Cai, L., Stefanovic, L., & Stefanovic, B. (2011). Progress towards discovery of antifibrotic drugs targeting synthesis of type I collagen. Curr Med Chem, 18 (22), 3410-6. Parsons, C. J., Stefanovic, B., Seki, E., Aoyama, T., Latour, A. M., Marzluff, W. F., Rippe, R. A., & Brenner, D. A. (2011). Mutation of the 5 '-Untranslated Region Stem-Loop Structure Inhibits alpha 1(I) Collagen Expression in Vivo. Journal of Biological Chemistry, 286(10), 8609-8619. Cai, L., Fritz, D., Stefanovic, L., & Stefanovic, B. (2010). Binding of LARP6 to the Conserved 5 ' Stem-Loop Regulates Translation of mRNAs Encoding Type I Collagen. J Mol Biol, 395(2), 309-326. Cai, L., Fritz, D., Stefanovic, L., & Stefanovic, B. (2010). Nonmuscle Myosin-Dependent Synthesis of Type I Collagen. J Mol Biol, 401(4), 564-578. Sakano, D., Kato, A., Parikh, N., McKnight, K., Terry, D., Stefanovic, B., & Kato, Y. (2010). BCL6 Canalizes Notch-Dependent Transcription, Excluding Mastermind-like1 from Selected Target Genes during Left-Right Patterning. Dev Cell, 18(3), 450-462 Fritz D, Stefanovic B. RNA binding protein RBMS3 is expressed in activated hepatic stellate cells and liver fibrosis and increases expression of transcription factor Prx1. J.Mol.Biol. 2007; 17;371(3):585-95. Jiang F, Stefanovic B. Homeobox Gene Prx1 Is Expressed in Activated Hepatic Stellate Cells and Transactivates Collagen {alpha}1(I) Promoter. Exp Biol Med. 2008: 233(3):286-96. Cai L, Fritz D, Stefanovic L, Stefanovic B. Coming together: liver fibrosis, collagen mRNAs and the RNA binding protein. Expert Rev. Gastroenterol. Hepatol. 3(1), 2009