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Postdoc, Molecular Genetics, Indiana University and the Howard Hughes Medical Institute PhD, Biochemistry, The University of North Carolina at Chapel Hill BS, Biochemistry, The State University of New York at Stony Brook

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Zheng Y, Mennella V, Marks S, Wildonger J, Elnagdi E, Agard D, Megraw T.L.The Seckel syndrome and centrosomal protein Ninein localizes asymmetrically to stem cell centrosomes, but is not required for normal development, behavior, or DNA damage response in Drosophila.Molecular Biology of the Cell. 2016 Apr 6. Chen, J. V., Kao, L.R., Jana, S.C., Sivan-Loukianova, E., Mendon?a, S., Cabrera, O.A., Singh, P., Cabernard, C., Eberl, D.F., Bettencourt-Dias, M., and Megraw, T. L. (2015).Rootletin organizes the ciliary rootlet to achieve neuron sensory function in Drosophila.Journal of Cell Biology (In Press) Tozser, J., Earwood, R., Kato, A., Brown, J., Tanaka, K., Didier, R., Megraw, T. L., Blum, M., and Kato, Y. (2015).TGF-beta Signaling Regulates the Differentiation of Motile Cilia.Cell reports 11, 1000-1007. Man, X., Megraw, T. L., and Lim, Y.P. (2015).Cep68 can be regulated by Nek2 and SCF complex.European Journal of Cell Biology 94, 162-172. Bingol, K., Li, D.W., Bruschweiler-Li, L., Cabrera, O.A., Megraw, T., Zhang, F., and Bruschweiler, R. (2015).Unified and isomer-specific NMR metabolomics database for the accurate analysis of (13)C-(1)H HSQC spectra.ACS chemical biology 10, 452-459. Galletta, B.J., Guillen, R.X., Fagerstrom, C.J., Brownlee, C.W., Lerit, D.A., Megraw, T. L., Rogers, G.C., and Rusan, N.M. (2014).Drosophila pericentrin requires interaction with calmodulin for its function at centrosomes and neuronal basal bodies but not at sperm basal bodies.Molecular Biology of the Cell 25, 2682-2694. Chen, J.V., and Megraw, T. L. (2014).Mother centrioles do a cartwheel to produce just one daughter.Developmental Cell 30, 111-112. Chen, J.V., and Megraw, T. L. (2014).Spermitin: a novel mitochondrial protein in Drosophila spermatids.PloS ONE 9, e108802. Riparbelli, M.G., Cabrera, O.A., Callaini, G., and Megraw, T. L. (2013).Unique properties of Drosophila spermatocyte primary cilia.Biology Open 2, 1137-1147. ----------This article was featured on the cover Chen, J.V., and Megraw, T. L. (2013).Cenexin1 and Odf2: splice variants with diverged cilium functions.Cell Cycle 12, 869. Riparbelli, M.G., Callaini, G., and Megraw, T. L. (2012).Assembly and persistence of primary cilia in dividing Drosophila spermatocytes.Developmental Cell 23, 425-432. Kao, L.R. and Megraw, T. L. (2012) Cytokinesis: RhoGEF controls a developmental cleavage switch.Curr Biol 22: 916-17. Gopalakrishnan, J., Mennella, V., Blachon, S., Zhai, B., Smith, A. H., Megraw, T. L., Nicastro, D., Gygi, S. P., Agard, D. A., & Avidor-Reiss, T. (2011). Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome. Nature communications, 2, 359. Megraw, T. L., Sharkey, J. T., & Nowakowski, R. S. (2011). Cdk5rap2 exposes the centrosomal root of microcephaly syndromes. Trends Cell Biol., 21: 470-480. NIHMS300507 Megraw, T. (2011)PP2A targets SAS-5 in centriole assembly Dev Cell, 20: 416-417. Invited commentary. PMC3104853 Barrera, J. A., Kao, L. R., Hammer, R. E., Seemann, J., Fuchs, J. L., & Megraw, T. L. (2010). CDK5RAP2 regulates centriole engagement and cohesion in mice. Dev Cell, 18(6), 913-26.----------This article was featured on the cover Kao, L. R., & Megraw, T. L. (2009). Centrocortin cooperates with centrosomin to organize Drosophila embryonic cleavage furrows. Current Biology, 19(11), 937-42. Mottier-Pavie, V., & Megraw, T. L. (2009). Drosophila bld10 is a centriolar protein that regulates centriole, basal body, and motile cilium assembly. Mol Biol Cell, 20(10), 2605-14.----------This article was featured on the cover Kotadia, S., Kao, L. R., Comerford, S. A., Jones, R. T., Hammer, R. E., & Megraw, T. L. (2008). PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigen. Oncogene, 27(49), 6334-46. Zhang, J. and Megraw, T. L. (2007) Motif 1 of Centrosomin recruits gamma-Tubulin and D-TACC/Msps to embryonic Drosophila centrosomes. Mol Biol Cell, 18, 4037-49. PMC1995719

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