ZHU, FANXIU - Florida State University

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Ph.D., Wuhan University, 1995

近期论文

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Avey D, Tepper S, Pifer B, Bahga A, Williams H, Gillen J, Li W, Ogden S, Zhu F. 20016. Discovery of a co-regulatory interaction between KSHV ORF45 and the viral protein kinase ORF36. J Virol. 90:5953-5964. Li W, Avey D, Fu B, Wu JJ, Ma S, Liu X, Zhu F. 2016. KSHV inhibitor of cGAS (KicGAS) encoded by ORF52 is an abundant tegument protein and required for production of infectious progeny viruses. J Virol. 90:5329-5342. Wu JJ, Avey D, Li W, Gillen J, Fu B, Miley W, Whitby D, Zhu F. 2016. ORF33 and ORF38 of Kaposi's Sarcoma-Associated Herpesvirus Interact and are Required for Optimal Production of Infectious Progeny Viruses. J Virol. 90:1741–1756. Sexton BS, Druliner BR, Vera DL, Avey D, Zhu F, Dennis JH. 2016. Hierarchical regulation of the genome: global changes in nucleosome organization potentiate genome response. Oncotarget. 7:6460-6475. Wang X, Zhu N, Li W, Zhu F, Wang Y, Yuan Y. 2015. Mono-ubiquitylated ORF45 Mediates Association of KSHV Particles with Internal Lipid Rafts for Viral Assembly and Egress. PLoS Pathog. 11:e1005332. Wu JJ, Li W, Shao Y, Avey D, Fu B, Gillen J, Hand T, Ma S, Liu X, Miley W, Konrad A, Neipel F, Stürzl M, Whitby D, Li H, Zhu F. 2015. Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein. Cell Host & Microbe. 18:333-44. Commentary Preview by Benjamin Diner and Ileana Cristea. FSU press release. Features in NIDCR E-Newsletter, Science Advances. Avey D, Tepper S, Li W, Turpin Z, Zhu F. 2015. Phosphoproteomic Analysis of KSHV-Infected Cells Reveals Roles of ORF45-Activated RSK during Lytic Replication. PLoS Pathogens. 11:e1004993. Li X, Du S, Avey D, Li Y, Zhu F, Kuang E. 2015. Inhibition ORF45-Mediated Prolonged c-Fos Accumulation Accelerates Viral Transcription during the Late Stage of Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 89:195-207. Gillen J, Li W, Liang Q, Avey D, Wu J, Wu F, Myoung J, Zhu F. 2015. A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is required for production of progeny viruses. J Virol. 89:4918-4931. Avey D, Brewers B, Zhu F. 2015. Recent advances in the study of Kaposi's sarcoma-associated herpesvirus replication and pathogenesis. Virologica Sinica. 30:130-145. Fu B, Kuang E, Li W, Avey D, Li X, Turpin Z, Valdes A, Brulois K, Myoung J, Zhu F. 2015. Activation of p90 ribosomal S6 kinases by ORF45 of Kaposi's sarcoma-associated herpesvirus is critical for optimal production of infectious viruses. J Virol. 89:195-207. Sexton BS, Druliner BR, Avey D, Zhu F, Dennis JH. 2014. Changes in nucleosome occupancy occur in a chromosome specific manner. Genomics Data. 2:114-116. Sexton BS, Avey D, Druliner BR, Fincher JA, Vera DL, Grau DJ, Borowsky ML, Gupta S, Girimurugan SB, Chicken E, Zhang J, Noble WS, Zhu F, Kingston RE, Dennis JH. 2014. The spring-loaded genome: nucleosome redistributions are widespread, transient, and DNA-directed. Genome Res. 24:251-259. Liang Q, Fu B, Wu F, Li X, Yuan Y, Zhu F. 2012. ORF45 of Kaposi's sarcoma–associated herpesvirus inhibits phosphorylation of interferon regulatory factory 7 by IKKε and TBK1 as an alternative substrate. J Virol. 86:10162-10172. Kuang E, Fu B, Liang Q, Myoung J, Zhu F. 2011. Phosphorylation of eukaryotic translation initiation factor 4B (eIF4B) by open reading frame 45/p90 ribosomal S6 kinase (ORF45/RSK) signaling axis facilitates protein translation during Kaposi sarcoma-associated herpesvirus (KSHV) lytic replication. J Biol Chem. 286:41171-41182. Liang Q, Deng H, Li X, Wu X, Tang Q, Chang TH, Peng H, Rauscher FJ 3rd., Ozato K, Zhu F. 2011. Tripartite Motif-Containing Protein 28 Is a Small Ubiquitin-Related Modifier E3 Ligase and Negative Regulator of IFN Regulatory Factor 7. J Immunol. 187:4754-4763. Featured In This Issue. Liang Q, Deng H, Sun CW, Townes TM, Zhu F. 2011. Negative Regulation of IRF7 Activation by ATF4 Suggests a Cross Regulation Between the Interferon Responses and the Cellular Integrated Stress Responses. J Immunol. 186:1001-1010. Sathish N, Zhu FX, Golub EE, Liang Q, Yuan Y. 2011. Mechanisms of auto-inhibition of IRF-7 and a probable model for inactivation of IRF-7 by Kaposis Sarcoma-associated herpesvirus protein ORF45. J Bio Chem. 286:746-756.