个人简介
Ph.D., University of California (Berkeley), 1975
近期论文
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Ping Zhu, Hanspeter Winkler, Kenneth A. Taylor & Kenneth H. Roux. Cryoelectron tomography of HIV-1 envelope spikes: further evidence for tripod-like legs. PLoS Pathogens, 4(11): e1000203. doi:10.1371/journal.ppat.1000203 (2008). PMCID: PMC2805068.
Cheri M. Hampton, Jun Liu, Dianne W. Taylor, David J. DeRosier & Kenneth A. Taylor. The 3D structure of villin as a unique F-actin cross-linker. Structure, 16(12), 1882-1891 (2008). PMCID: PMC2782859.
Hanspeter Winkler, Ping Zhu, Jun Liu, Feng Ye, Kenneth H. Roux & Kenneth A. Taylor. Tomographic subvolume alignment and subvolume classification applied to myosinV and SIV envelope spikes. J. Struct. Biol. 165(2), 64-77 (2009) PMCID: PMC2656979.
Jason O’Donnel, Kenneth A. Taylor & Michael S. Chapman. Adeno-Associated Virus-2 and its primary cellular receptor – cryo-EM structure of a heparin complex. Virology 385, 434–443 (2009). PMCID: PMC2684845.
Shenping Wu, Jun Liu, Mary C. Reedy, Hanspeter Winkler, Michael K. Reedy & Kenneth A. Taylor. Methods for identifying and averaging variable molecular conformations in tomograms of actively contracting insect flight muscle. J. Struct. Biol. 168, 485-502 (2009). PMCID: PMC2805068.
Feng Ye, Guiqing Hu, Dianne Taylor, Boris Ratnikov, Mark A. McLean, Stephen G. Sligar, Kenneth A. Taylor, and Mark H. Ginsberg. Recreation of the terminal events in physiological integrin activation. J. Cell Biol. 188(1), 157-173 (2010). PMCID: PMC2812850.
Shenping Wu, Jun Liu, Mary C. Reedy, Richard T. Tregear, Hanspeter Winkler, Clara Franzini-Armstrong, Hiroyuki Sasaki, Carmen Lucaveche, Yale E. Goldman, Michael K. Reedy & Kenneth A. Taylor. Electron tomography of cryofixed, isometrically contracting insect flight muscle reveals novel actin-myosin interactions. PLoS ONE 5(9), e12643 (2010). PMCID: PMC2936580
Guiqing Hu, Jun Liu, Kenneth A Taylor & Kenneth H. Roux. Structural Comparison of HIV-1 Envelope Spikes with and without the V1/V2 loop. J. Virology, 85(6), 2741–2750 (2011). PMCID: PMC3067966
Agnieszka Collins, Anthony Warrington, Kenneth A. Taylor & Tatyana Svitkina. Structural organization of the actin cytoskeleton at the sites of clathrin-mediated endocytosis. Current Biology, 21(14), 1167-1175 (2011). PMCID: PMC3143238
Pradeep Luther, Hanspeter Winkler, Kenneth Taylor, Maria-Elena Zoghbi, Roger Craig, Raul Padron, John Squire and Jun Liu. Direct visualisation of the binding of myosin binding protein C to actin filaments in intact muscle. Proc. Natl. Acad. Sci. 108(28), 11423-11428 (2011) PMCID: PMC3136262
Bruce A. J. Baumann, Dianne W. Taylor, Florence Tama, Patty Fagnant, Kathy Trybus & Kenneth A. Taylor. Phosphorylated smooth muscle heavy meromyosin shows an open conformation linked to activation. J. Mol. Biol. 415(2), 274–287 (2012). PMCID: PMC3295741
Dustin McCraw, Jason O'Donnell, Scott Stagg, Kenneth A. Taylor & Michael S. Chapman. Structure of Adeno-Associated Virus-2 in complex with neutralizing monoclonal antibody A20. Virology 431(1,2), 40-49 (2012)
Shenping Wu, Jun Liu, Mary C. Reedy, R. J. Perz-Edwards, Richard T. Tregear, Hanspeter Winkler, Clara Franzini-Armstrong, Hiroyuki Sasaki, Carmen Lucaveche, Yale E. Goldman, Michael K. Reedy & Kenneth A. Taylor. Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation. PLoS-ONE 7(6): e39422. (2012)
Thomas F. Lerch, Jason K. O’Donnell, Nancy L. Meyer, Qing Xie, Kenneth A. Taylor, Scott M. Stagg & Michael S. Chapman. Structure of AAV-DJ, a retargeted gene therapy vector: cryo-electron microscopy at 4.5 ? resolution. Structure 20(8), 1310-1320 (2012)
Hanspeter Winkler & Kenneth A. Taylor. Marker-free dual-axis tilt series alignment. J. Struct. Biol. 182(2), 117-124 (2013)
H. Winkler, S. Wu and K. A. Taylor. Electron Tomography of Paracrystalline 2-D Arrays. In: Methods in Molecular Biology, Y. Cheng and I. Schmidt-Krey, Editors. Academic Press, San Diego, CA. vol. 955, pgs. 427-60 (2013)
Hanspeter Winkler, Kenneth A. Taylor. Marker-free dual-axis tilt series alignment J. Struct. Biol. 182(2), 117-124 (2013) PMCID: PMC4098971
Kenneth A. Taylor, Meikel Feig, Charles L. Brooks, III, Susan Lowey, Patricia M. Fagnant and Kathleen M. Trybus. Role of the essential light chain in the activation of smooth muscle myosin by regulatory light chain phosphorylation. J. Struct. Biol. 185, 375–382 (2014) PMCID: PMC4065857
G. Márquez, A. Pinto, L. Alamo, B. A. J. Baumann, F. Ye, H. Winkler, K. Taylor & R. Padrón. A method for 3D-reconstruction of a muscle thick filament using the tilt series images of a single filament electron tomogram. J. Struct. Biol. 186(2), 265-72 (2014). PMCID: PMC4102135
Moumita Dutta, Jun Liu, Kenneth H. Roux, and Kenneth A. Taylor. Visualization of retroviral envelope spikes 1 in complex with a variable loop antibody on intact viruses by cryo-electron tomography. J. Virology 88(21) 12265-75 (2014) PMCID: PMC4248906
Claudia Arakelian, Anthony Warrington, Hanspeter Winkler, R. J. Perz-Edwards, Michael K. Reedy, and Kenneth A. Taylor. Myosin cross-bridge origins indicate azimuthal rolling of motor domain during the weak to strong binding transition. Biophys J. 108, 1495–1502 (2015)
Aguang Dai, Feng Ye, Dianne W. Taylor, Guiqing Hu, Mark H. Ginsberg, Kenneth A. Taylor. The Structure of a Full-length Membrane-embedded Integrin Bound to a Physiological Ligand. J. Biol. Chem. 290, 27168-27175 (2015)
Zhongjun Hu, Dianne W. Taylor, Michael K. Reedy, Robert J. Perz-Edwards and Kenneth A. Taylor. Structure of myosin filaments from relaxed Lethocerus flight muscle by cryo-EM at 6 ? resolution. Sci. Adv. 2, e1600058 (2016)