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Ming, Guo-li, Tang, Hengli and Song, Hongjun 2016 Dec 1. Advances in Zika Virus Research: Stem Cell Models, Challenges, and Opportunities doi: http://dx.doi.org/10.1016/j.stem.2016.11.014
Xu, M., Lee, EM.,Wen, Z., Cheng, Y., Huang, W., Qian, X., TCW, J., Kouznetsova, J., Ogden., SC., Hammack, C., Jacob, F., Nguyen, HN., Itkin, M., Hanna, C., Shinn, P., Allen, C., Michael, SG., Simeonov, A., Huang, W., Christian, KM., Goate, A., Brennand, KJ., Huang, R., Xia, M., Ming, G., Zheng, W., Song, H., Tang, H. 2016 Aug 22. Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen. Nature Medicine. doi:10.1038/nm.4184
Zhang, F., Hammack, C., Ogden, S. C., Cheng, Y., Lee, E. M., Wen, Z., Qian, X., Nguyen, H., Li ,Y., Yao, B., Xu, M., Xu, T., Chen, L., Wang, Z., Feng, H., Huang, W., Yoon, K., Shan, C., Huang, L., Qin, Z., Christian, K M., Shi, P., Xu, M., Xia, M., Zheng, W., Wu, H., Song, H., Tang, H., Ming, G., Jin, P. 2016 Aug 31. Molecular signatures associated with ZIKV exposure in human cortical neural progenitors. Nucleic Acids Research, doi:10.1093/nar/gkw765
Lang, J., Vera, D., Cheng, Y., & Tang, H. 2016 Aug 16. Modeling dengue virus-hepatic cell interactions using human pluripotent stem cell-derived hepatocyte-like cells. Stem Cell Reports, doi:http://dx.doi.org/10.1016/j.stemcr.2016.07.012
Qian, X., Ha Nam Nguyen, Song, M. M., Hadiono, C., Ogden, S. C., Hammack, C., Yao, B., Hamersky, GR., Jacob, F., Zhong, C., Yoon, KJ., Jeang, W., Lin, L., Li, YJ., Thakor, J., Berg, DA., Zhang, C., Kang, E., Chickering, M., Nauen, D., Ho, CY., Wen, ZX., Christian, KM., Shi, PY., Maher, BJ., Wu, H., Jin, P., Tang, HL., Song, HJ., Ming, G. 2016 May 19. Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure. Cell, 165(5), 1238-1254. doi:10.1016/j.cell.2016.04.032
Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM, Christian KM, Didier RA, Jin P, Song H, Ming GL. Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth. Cell Stem Cell. 2016 Mar 3. pii: S1934-5909(16)00106-5. doi: 10.1016/j.stem.2016.02.016. [Epub ahead of print]
Lee EM, Alsagheir A, Wu X, Hammack C, McLauchlan J, Watanabe N, Wakita T, Kneteman NM, Douglas DN, Tang H. Hepatitis C virus induced degradation of cell death-inducing DFFA-like effector B leads to hepatic lipid dysregulation. J Virol. 2016 Feb 10. pii: JVI.02891-15. [Epub ahead of print]
Hookway TA, Butts JC, Lee E, Tang H, McDevitt TC. Aggregate formation and suspension culture of human pluripotent stem cells and differentiated progeny. Methods. 2015 Dec 2. pii: S1046-2023(15)30167-5. doi: 10.1016/j.ymeth.2015.11.027. [Epub ahead of print]
Ogden SC, Tang H. The missing pieces of the HCV entry puzzle. Future Virol. 2015;10(4):415-428.
Lee T, Di Paola D, Malina A, Mills JR, Kreps A, Grosse F, Tang H, Zannis-Hadjopoulos M, Larsson O, Pelletier J. Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner. J Biol Chem. 2014 Aug 15;289(33):22798-814. doi: 10.1074/jbc.M114.568535. Epub 2014 Jul 2.
Wu X, Lee EM, Hammack C, Robotham JM, Basu M, Lang J, Brinton MA, Tang H. Cell death-inducing DFFA-like effector b is required for hepatitis C virus entry into hepatocytes. J Virol. 2014 Aug;88(15):8433-44. doi: 10.1128/JVI.00081-14. Epub 2014 May 14
Yu F, Peng Y, Wang Q, Shi Y, Si L, Wang H, Zheng Y, Lee E, Xiao S, Yu M, Li Y, Zhang C, Tang H, Wang C, Zhang L, Zhou D. Development of bivalent oleanane-type triterpenes as potent HCV entry inhibitors. Eur J Med Chem. 2014 Apr 22;77:258-68. doi: 10.1016/j.ejmech.2014.03.017. Epub 2014 Mar 7.
Che P, Tang H, Li Q. The interaction between claudin-1 and dengue viral prM/M protein for its entry. Virology. 2013 Nov;446(1-2):303-13. doi: 10.1016/j.virol.2013.08.009. Epub 2013 Sep 7.
Frausto SD, Lee E, Tang H. Cyclophilins as modulators of viral replication.Viruses. 2013 Jul 11;5(7):1684-701. doi: 10.3390/v5071684. Review.
Jiang J, Wu X, Tang H, Luo G. Apolipoprotein E mediates attachment of clinical hepatitis C virus to hepatocytes by binding to cell surface heparan sulfate proteoglycan receptors. PLoS One. 2013 Jul 2;8(7):e67982. doi: 10.1371/journal.pone.0067982. Print 2013.
Wu X, Robotham JM, Lee E, Dalton S, Kneteman NM, Gilbert DM, Tang H. Productive Hepatitis C Virus Infection of Stem Cell-Derived Hepatocytes Reveals a Critical Transition to Viral Permissiveness during Differentiation. PLoS Pathog. 2012 Apr;8(4):e1002617. Epub 2012 Apr 5.
Nag A, Robotham JM, Tang H. Suppression of Viral RNA Binding and the Assembly of Infectious Hepatitis C Virus Particles in vitro by Cyclophilin Inhibitors. J Virol. 2012 Sep 12. [Epub ahead of print]
Grisé H, Frausto S, Logan T, Tang H. A Conserved Tandem Cyclophilin-Binding Site in Hepatitis C Virus Nonstructural Protein 5A Regulates Alisporivir Susceptibility. J Virol. 2012 May;86(9):4811-22. Epub 2012 Feb 15.
Jiang J, Cun W, Wu X, Shi Q, Tang H, Luo G. Hepatitis C virus attachment mediated by apolipoprotein E binding to cell surface heparan sulfate. J Virol. 2012 Jul;86(13):7256-67. Epub 2012 Apr 24
Hebner CM, Han B, Brendza KM, Nash M, Sulfab M, Tian Y, Hung M, Fung W, Vivian RW, Trenkle J, Taylor J, Bjornson K, Bondy S, Liu X, Link J, Neyts J, Sakowicz R, Zhong W, Tang H, Schmitz U. The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function. PLoS One. 2012;7(6):e39163. Epub 2012 Jun 13.
Yang F, Robotham JM, Grise H, Frausto S, Madan V, et al. (2010) A Major Determinant of Cyclophilin Dependence and Cyclosporine Susceptibility of Hepatitis C Virus Identified by a Genetic Approach. PLoS Pathog 6(9): e1001118. doi:10.1371
Tang H. Cyclophilin Inhibitors as a Novel HCV Therapy. Viruses. 2010; 2(8):1621-1634.
Tang H, Grisé H. Cellular and molecular biology of HCV infection and hepatitis. Clin Sci (Lond). 2009 Jun 15;117(2):49-65.
Kenworthy R, Lambert D, Yang F, Wang N, Chen Z, Zhu H, Zhu F, Liu C, Li K, Tang H. Short-hairpin RNAs delivered by lentiviral vector transduction trigger RIG-I-mediated IFN activation. Nucleic Acids Res. 2009 Oct;37(19):6587-99. Epub 2009 Sep 3.
Liu Z, Robida JM, Chinnaswamy S, Yi G, Robotham JM, Nelson HB, Irsigler A, Kao CC, Tang H. Mutations in the hepatitis C virus polymerase that increase RNA binding can confer resistance to cyclosporine A. Hepatology. 2009 Jul;50(1):25-33.
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