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研究领域

Dr. Harper-Leatherman's research focuses on studying the spectroscopic and electrochemical characteristics of proteins encapsulated within aerogels. Aerogels are highly porous solids with high surface areas making them ideal for applications in catalysis, sensing, batteries, or fuel cells in which numerous, efficient surface reactions are important. Exploring biofunctionality within aerogels will enhance knowledge of how protein environment and organization effect protein properties, and will aid in the future development of bioanalytical devices.

近期论文

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Harper-Leatherman, A. S.; Wallace, J. M.; Rolison, D. R. Cytochrome c stabilization and immobilization in aerogels. In Enzyme Stabilization: Methods and Protocols; S. D. Minteer, Ed.; Humana Press: New York, NY, 2011; Vol. 679, pp 193-205. Menard, L. D.; Xu, H.; Gao, S.-P.; Twesten, R. D.; Harper, A. S.; Song, Y.; Wang, G.; Douglas, A. D.; Yang, J. C.; Frenkel, A. I.; Murray, R. W.; Nuzzo, R. G., "Metal Core Bonding Motifs of Monodisperse Icosahedral Au13 and Larger Au Monolayer-Protected Clusters As Revealed by X-ray Absorption Spectroscopy and Transmission Electron Microscopy," J. Phys. Chem. B 2006, 110, 14564-14573. Menard , L. D.; Gao, S.-P.; Xu, H; Twesten, R. D.; Harper, A. S.; Song, Y.; Wang, G.; Douglas, A. D.; Yang, J. C.; Frenkel, A. I.; Nuzzo, R. G.; Murray, R. W., "Sub-Nanometer Au Monolayer-Protected Clusters Exhibiting Molecule-like Electronic Behavior: Quantitative High-Angle Annular Dark-Field Scanning Transmission Electron Microscopy and Electrochemical Characterization of Clusters with Precise Atomic Stoichiometry," J. Phys. Chem. B 2006, 110, 12874-12883. Harper, A. S.; Leone, A. M.; Lee, D.; Wang, W.; Ranganathan, S.; Williams, M. E.; Murray, R. W., "Ion atmosphere relaxation controlled electron transfers in cobaltocenium polyether molten salts," J. Phys. Chem. B 2005, 109, 18852-18859. Song, Y.; Harper, A. S.; Murray, R. W., "Ligand heterogeneity on monolayer-protected gold clusters," Langmuir 2005, 21, 5492-5500. Jimenez, V. L.; Georganopoulou, D. G.; White R. J.*; Harper, A. S.; Mills, A. J.; Lee, D.; Murray, R. W., "Hexanethiolate monolayer protected 38 gold atom cluster," Langmuir 2004, 20, 6864-6870. Lee, D.; Donkers, R. L.; Wang, G.; Harper, A. S.; Murray, R. W., "Electrochemistry and optical absorbance and luminescence of molecule-like Au38 nanoparticles," J. Am. Chem. Soc. 2004, 126, 6193-6199. Harper, A. S.; Lee, D.; Crooker, J. C.; Wang, W.; Williams, M. E.; Murray, R. W., "Parallel variation of mass transport and heterogeneous and homogeneous electron transfer rates in hybrid redox polyether molten salts," J. Phys. Chem. B 2004, 108, 1866-1873. Lee, D.; Harper, A. S.; DeSimone, J. M.; Murray, R. W., "Ion atmosphere relaxation control of electron transfer dynamics in a plasticized carbon dioxide redox polyether melt," J. Am. Chem. Soc. 2003, 125, 1096-1103.

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