吴海波 - 重庆大学 - 生命科学学院

个人简介

2018年7月任重庆大学百人计划学者，博士生导师。以主持人身份主持国家自然基金等省部级以上项目6项，以主要参加人身份参与国家转基因生物新品种培育重大专项，国家高新技术研究发展计划，国家自然科学基金重点项目等重大科研项目3项。以第一作者或通讯作者署名发表SCI论文10篇，累计影响因子超过60。

研究领域

研究细菌或病毒（目前主要为结核分枝杆菌）在侵入机体过程中，宿主的免疫应答反应以及客体的免疫逃避机制。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Wu H#, Wu Y, Ai Z, Yang L, Gao Y, Du J, Guo Z, Zhang Y*. Vitamin C enhances nanog expression via activation of the JAK/STAT signaling pathway. Stem Cells. 32(1):166-76, 2014. (中科院1区，IF=7.701) 2. Wu H#, Wang Y, Zhang Y, Yang M, Lv J, Liu J, and Zhang Y*. TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis. Proc Natl Acad Sci U S A, Mar 31; 112(13): E1530–E1539, 2015. (中科院1区，IF=9.809. Featured article, highlighted by Christopher K. Tuggle, Proc Natl Acad Sci U S A, 112(13): 3854-3855, 2015) 3. Gao Y#, Wu H#, Wang Y#, Liu X, Chen L, Li Q, Cui C, Liu X, Zhang J, Zhang Y*. Single Cas9 nickase induced generation of NRAMP1 knockin cattle with reduced off-target effects. Genome Biol;18(1):13,2017. (中科院1区，IF=11.908) 4. Wu H#*, Song C, Zhang J, Zhao J, Fu B, Mao T, Zhang Y*.Melatonin-mediated upregulation of GLUT1 blocks exit from pluripotency by increasing the uptake of oxidized vitamin C in mouse embryonic stem cells. FASEB J;31(4):1731-1743, 2017. (中科院2区TOP，IF=5.498) 5. Wu H#*, Zhao J, Fu B, Yin S, Song C, Zhang J, Zhao S, Zhang Y*. Retinoic acid-induced upregulation of miR-219 promotes the differentiation of embryonic stem cells into neural cells. Cell Death Dis;8(7):e2953,2017. (中科院2区，IF=5.965) 6. Song C, Zhao J, Fu B, Dan Li, Mao T, Peng W, Wu H*, Zhang Y*. Melatonin-mediated upregulation of Sirt3 attenuates sodium fluoride-induced hepatotoxicity by activating the MT1-PI3K/AKT-PGC-1α signaling pathway.Free Radic Biol Med;112:616-630, 2017. (中科院2区TOP，IF=5.605) 7. Song C, Fu B, Zhang J, Zhao J, Yuan M, Peng W, Zhang Y*, Wu H*. Sodium fluoride induces nephrotoxicity via oxidative stress-regulated mitochondrial SIRT3 signaling pathway. Sci Rep. 6;7(1):672,2017. (中科院2区，IF=5.228) 8. Song C, Peng W, Yin S, Zhao J, Fu B, Zhang J, Mao T, Wu H*, Zhang Y*. Melatonin improves age-induced fertility decline and attenuates ovarian mitochondrial oxidative stress in mice. Sci Rep. 12;6:35165,2016. (中科院2区，IF=5.578) 9. Fu B, Zhao J, Peng W, Wu H*, Zhang Y*. Resveratrol rescues cadmium-induced mitochondrial injury by enhancing transcriptional regulation of PGC-1α and SOD2 via the Sirt3/FoxO3a pathway in TCMK-1 cells. Biochemical and Biophysical Research Communications, 486(1): 198-204, 2017. 10. Zhao J, Fu B, Peng W, Mao T, Wu H*, Zhang Y*. Melatonin protect the development of preimplantation mouse embryos from sodium fluoride-induced oxidative injury. Environmental Toxicology and Pharmacology, 54, 133-141, 2017.