林正红 - 重庆大学 - 生命科学学院

个人简介

教育背景： 2003-2008：清华大学，生物科学与技术系，博士 1998-2001：中国农业科学院研究生院，硕士 1994-1998：中国农业大学，动物科技学院，学士科研经历： 2014.12-现在：重庆大学生命科学学院‘百人计划’学者、研究员、博士生导师 2012.07-2014.11：美国西北大学，Feinberg School of Medicine，研究助理教授 2009.12-2012.06：美国西北大学，Feinberg School of Medicine, 研究助理 2009.1-2009.11：美国芝加哥大学，Ben May癌症生物学系，博士后 2008.09-2009.01：美国匹兹堡大学，医学院，博士后

研究领域

分子细胞生物学

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.Ling Dong; Le Yu; Chunrong Bai; Liu Liu; Hua Long; Lei Shi; Zhenghong Lin*. USP27-mediated Cyclin E Stabilization Drives Cell Cycle Progression and Hepatocellular Tumorigenesis. Oncogene, 2018 Mar, 10(1038) ; SCI 1区 2. Lei Shi*; Lihua Yu; Fagu iZou; Huimin Hu; Kun Liu; Zhenghong Lin*. Gene expression profiling and functional analysis reveals that p53 pathway-related gene expression is highly activated in cancer cells treated by cold atmosphe c plasma-activated medium. Peer J, 2017 Aug, 5: e3751; 3. Yuqiong Wang; Xiyu Zhang; Wei Tang; Zhenghong Lin; Limei Xu; Ruifen Dong; Yiluo Li; Jieyin Li; Zaixin Zhang; Xiangzhi Li; Ling Zhao; Jian-jun Wei; Changshun Shao; Beihua Kong; Zhaojian Liu. miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma. Cell Death Differ, 2017 Dec, 24(12): 2089~2100 ; SCI 1区 4. Yan Wu，Chunxiang Bian，Chunlin Zhen，Liu Liu，Zhenghong Lin，Muhammad Farrukh Nisar，Mei Wang，Joerg W.Bartsch，Enyi Huang，Ping Ji，Li Yang，Yanhong Yu，Junfeng Yang，Xuemei Jiang，Julia Li Zhong,*. Telomerase reverse transcriptase mediates EMT through NF-kappa B signaling in tongue squamous cell carcinoma. ONCOTARGET，2017.10.17，8（49）：85492~85503; 5. Xuebao Zhang，Juan Cai，Ze Zheng，Lisa Polin，Zhenghong Lin，Aditya Dandekar，Li Li，Fei Sun，Russell L Finley Jr，Deyu Fang，Zeng-Quan Yang，Kezhong Zhang*. A novel ER–microtubule-binding protein, ERLIN2, stabilizes Cyclin B1 and regulates cell cycle progression. Cell Discovery，2015.9.8，1：15024 6. Sinyi Kong，Hongxin Dong，Jianxun Song，Muthusamy Thiruppathi，Bellur S.Prabhakar，Quan Qiu，Zhenghong Lin，Chini, Eduardo，Bin Zhang，Deyu Fang. Deleted in Breast Cancer 1 Suppresses B Cell Activation through RelB and Is Regulated by IKK alpha Phosphorylation. JOURNAL OF IMMUNOLOGY，2015.10.15，195（8）：3685~3693 ; 7. Lin Z*. SIRT7: from a Metabolic Regulator to a Disease Marker International Journal of Cancer Studies & Research (IJCR), 2015.2.23, 4(1): 63~66 ; 8. Zhenghong Lin; Can Tan; Quan Qiu; Sinyi Kong; Heeyoung Yang; Fang Zhao; Zhaojian Liu; Jinping Li; Qingfei Kong; Beixue Gao; Terry Barrett; Guang-Yu Yang; Jianing Zhang; Deyu Fang*. Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1. Cell Discov, 2015 Apr, 1: 15028 9. Heeyoung Yang, Quan Qiu, Beixue Gao, Sinyi Kong, Zhenghong Lin and Deyu Fang. Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation.J Exp Med. 2014 Nov 3 . (影响因子13.9) 10. Sinyi Kong, Muthusamy Thiruppathi, Quan Qiu, Zhenghong Lin, Hongxin Dong, Bellur S. Prabhakar, Eduardo Nunes Chini and Deyu Fang. DBC1 Is a Suppressor of B Cell Activation by Negatively Regulating Alternative NF-кB Transcriptional Activity. J Immunol.2014 Oct 31 . (影响因子5.5) 11. Zhenghong Lin* and Jinping Li. SIRT6 Links Immune Response and Metabolism to Cancer.Austin J Clin Pathol.2014;1(1) (*corresponding author) 12. Zhenghong Lin, Heeyoung Yang, Can Tan, Jinping Li, Zhaojian Liu, Qiu Quan, Sinyi Kong, Junsheng Ye, Beixue Gao and Deyu Fang. The Deubiquitinase USP10 Antagonizes c-Myc Transcriptional Activation through SIRT6 Stabilization to Suppress Tumor Formation. Cell Reports.2013 Dec 11. (影响因子7.2) 13. Kyeorda L. Kemp, Zhenghong Lin, Fang Zhao, Beixue Gao, Jianxun Song, Kezhong Zhang and Deyu Fang. The serine-threonine kinase Inositol-requiring enzyme 1 α (IRE1α) promotes IL-4 production in T helper cells.J Biol Chem.2013 Nov 15;288(46):33272-82 . (影响因子4.7) 14. Quan Qiu, Ze Zheng, Lin Chang, Yuan-Si Zhao, Can Tan, Aditya Dandekar, Zheng Zhang, Zhenghong Lin, Ming Gui, Xiu Li, Tongshuai Zhang, Qingfei Kong, Hulun Li, Sha Chen, An Chen, Randal J Kaufman, Wei-Lei Yang, Hui-Kuan Lin, Donna Zhang, Harris Perlman, Edward Thorp, Kezhong Zhang, and Deyu Fang.Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis. EMBO J. 2013 Aug 13. (影响因子10.8) 15. Po-Han Chen, Xiaoyan Chen, Zhenghong Lin, Deyu Fang, and Xiaolin He.The structural basis of R-spondin recognition by LGR5 and RNF43.Genes Dev.2013 Jun 11. (影响因子12.3)