夏玉先 - 重庆大学 - 生命科学学院

个人简介

夏玉先，教授，1964年生，教授(二级)、博士生导师、生物学一级学科博士点学术带头人、教育部“新世纪优秀人才”、重庆市百名杰出科技领军人才、重庆市微生物学科带头人、《中国生物防治学报》副主编、农业农村部专家指导委员会委员、国家标准委员会生物农药分委会副秘书长。现任重庆大学基因工程研究中心主任、重庆市“杀虫真菌农药工程技术研究中心”主任、重庆市功能基因与调控技术重点实验室主任。主要从事杀虫真菌农药研制相关的基础研究和应用技术研究。先后主持国家级和省部级科研、中试和产业化项目20多项；主持完成的研究成果获2009年度重庆市技术发明一等奖和2010年获中国侨界贡献奖（创新成果），获得国家发明专利20项。以第一或通讯作者在PLoS Genetics, Environmental Microbiology, Microbiology-SGM, BMC Genomics，Applied Microbiology and Biotechnology等著名学术刊物发表SCI收录论文60多篇；获得国家发明专利20项。学习经历： 1997-2000 英国Bath大学获博士学位（英国海外研究学生奖学金） 1988-1991 西南农业大学获硕士学位 1981-1985 四川农业大学获学士学位工作经历 1996-1997 英国Bath大学访问学者（中英友好奖学金） 1991-1997 西南大学历任助教、讲师、副教授 2000-至今重庆大学教授

研究领域

分子微生物学、昆虫病理学、微生物分子育种

近期论文

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【1】Zhang E。 , Cao Y., Xia Y。 Ethanol dehydrogenase I contributes to growth and sporulation under low oxygen condition via detoxification of acetaldehyde in Metarhiziumacridum，Front. Microbiol.2018，9:1932 【2】Li G., Fan A., Peng G., Keyhani NO., Xin J., Cao Y. Xia Y，A bifunctional catalase-peroxidase, MakatG1, contributes to virulence of Metarhizium acridum by overcoming oxidative stress on the host insect cuticle，Environ Microbiol，2017,19(10): 4365–4378 【3】Zhang W, Chen J, Keyhani NO, Jin K, Wei Q, Xia Y，Central Nervous System Responses of the Oriental migratory, Locusta migratoria manilensis, to Fungal Infection.Sci Rep.2017 ;7(1):1034 【4】Zhang J,Jin K, Xia Y,Contributions of β-tubulin to cellular morphology, sporulation and virulence in the insect-fungal pathogen, Fungal Genet Biol.2017, 103:16-24 【5】Hong M.，Peng G., Keyhani NO, Xia Y.Application of the entomogenous fungus, Metarhizium anisopliae, for leafroller (Cnaphalocrocis medinalis) control and its effect on rice phyllosphere microbial diversity，Appl Microbiol Biotechnol，2017,101:6793–6807 【6】Hu J, Xia Y.Increased virulence in the locust-specific fungal pathogen Metarhizium acridum expressing dsRNAs targeting the host F1 F0 -ATPase subunit genes.Pest Manag Sci，2018 May 23. doi: 10.1002/ps.5085 【7】Hu J, Xia Y.F1-ATP synthase α subunit: a potential target for RNAi-mediated pest management of Locusta migratoria manilensis.Pest Manag Sci2016, 72:1433- 1439 【8】 Wang ZL, Jin K, Xia YX. Transcriptional analysis of the conidiation pattern shift of the entomopathogenic fungus Metarhizium acridum in response to different nutrients. BMC Genomics. 2016, 17: 586. 【9】 Zhang W., Wanchoo A., Ortiz-Urquiza., Yuxian Xia, and Nemat O. Keyhani. Tissue, developmental, and caste-specific expression of odorant binding proteins in a eusocial insect, the red imported fire ant, Solenopsis invicta. Scientific Reports, 2016, 6. 【10】 Jin K, Peng GX, Liu YC, Xia YX. The acid trehalase, ATM1, contributes to the in vivo growth and virulence of the entomopathogenic fungus, Metarhizium acridum. Fungal Genetics and Biology. 2015, 77: 61-67. 【11】 Ma QS, Jin K, Peng GX, Xia YX. An ENA ATPase, MaENA1, of Metarhizium acridum influences the Nai+-, thermo- and UV-tolerances of conidia and is involved in multiple mechanisms of stress tolerance. Fungal Genetics and Biology.2015, 83: 68-77. 【12】 Peng GX, Jin K, Liu YC, Xia YX. Enhancing the utilization of host trehalose by fungal trehalase improves the virulence of fungal insecticide. Applied Microbiology and Biotechnology. 2015, 99(20):8611-8618. 【13】 Zhang W, Chen J, Keyhani NO, Zhang Z, Li S, Xia Y. Comparative transcriptomic analysis of immune responses of the migratory locust, Locusta migratoria, to challenge by the fungal insect pathogen, Metarhizium acridum. BMC genomics 2015, 16: 867- 【14】 Ming Y, Wei QL, Jin K, Xia YX. MaSnf1, a sucrose non-fermenting protein kinase gene, is involved in carbon source utilization, stress tolerance and virulence in Metarhizium acridum. Applied Microbiology and Biotechnology. 2014, 98: 10153-10164. 【15】 Cao Y., Du M., Luo S., Xia Y. Calcineurin modulates growth, stress tolerance, and virulence in Metarhizium acridum and its regulatory network. Applied Microbiology and Biotechnology. 2014, 98: 8253-8265 【16】 Zhang W., Xia Y. ER type I signal peptidase subunit (LmSPC1) is essential for the survival of Locusta migratoria manilensis and