个人简介
Ph.D., Brandeis Univ. (1987)
B.A., College of the Holy Cross (1980)
研究领域
Cell to Cell Communication
Molecular Genetics
Signal Transduction
Nuclear Trafficking
Cellular Differentiation
近期论文
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Fleming, Robert J. “Notch Signaling,” AccessScience (McGraw-Hill Education, 2014).
Fleming, Robert J., Hori, Kazuya, Sen, Anindya, Filloramo, Gina V., Langer, Jillian M., Obar, Robert A., Artavanis-Tsakonas, Spyros and Maharaj-Best, Ayiti C. "An extracellular region of Serrate is essential for ligand-induced cis-inhibition of Notch signaling." Development 140 (2013): 2039-2049.
Ratan, R., Mason, D.A., Sinnot, B., Goldfarb, D.S. and Fleming, R. J. "Drosophila importin a1 performs paralog-specific functions essential for gametogenesis." Genetics 178 (2008): 839-850.
Trang, T.T., Tannous, V., Gu, Y., Mosher, J. and Fleming, R. J. "Ser+r83k is a second site mutation of SerD affecting the N-terminus of Serrate." Genesis 39 (2004): 42-51.
Yan, S-J., Gu, Y., Li, W.X., and Fleming, R.J. "Multiple signaling pathways and a selector protein sequentially regulate Drosophila wing development." Development 131 (2004): 285-298.
Mason, D. A., Máthé, E., Fleming, R. J. and Goldfarb, D. S. "The Drosophila melanogaster importin a3 locus encodes an essential gene required for the development of both larval and adult tissues." Genetics 165 (2003): 1943-1958.
Mason, D. A., Fleming, R. J. and Goldfarb, D. S. "Drosophila melanogaster Importin a1 and a3 can replace importin a2 during spermatogenesis but not oogenesis." Genetics 161 (2002): 157-170.
Fleming, R. J. "Structural conservation of Notch receptors and ligands." Semin Cell Dev Biol. 9 (1998): 599-607.