Chakraborty, Sourav - Central Connecticut State University - Department of Chemistry & Biochemistry

个人简介

Dr. Chakraborty is an interdisciplinary scientist who is skilled at developing method for complex matrices. He received his classical analytical chemistry training from Dr. Matthew Tarr at University of New Orleans. In collaboration with Dr. Yang Cai, he developed a free radical footprinting method for mapping apolipoprotein B-100 oxidation sites using liquid chromatography - tandem mass spectrometry techniques. These oxidations play important role in atherosclerotic plaque formation. Dr. Chakraborty was further mentored in plant metabolomics and large scale proteomics research by chemical ecologist Dr. Enrico Bonello at the Ohio State University and had opportunity to collaborate with leading experts in the field. During his tenure as a postdoctoral researcher, Dr. Chakraborty integrated research at the interface of chemistry, biology and environmental science studying plant-insect interactions using ash (Fraxinus spp.) and emerald ash borer (Agrilus plannipenis F.) as a model system. His research shed light on induced metabolomic and proteomic putative biomarkers of resistance in ash trees against emerald ash borer.

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Chakraborty, S.; Hill, A.L.; Shirsekar, G.; Afzal, A.; Wang, G.-L.; Mackey, D; Bonello, P., Quantification of hydrogen peroxide in plant tissues using Amplex Red, Methods. (2016). doi:10.1016/j.ymeth.2016.07.016. (post-refereed version available from Chakraborty_Methods_2016_post-review proof) Lieurance, D.; Chakraborty, S.; Whitehead, S. R.; Powell, J.; Bonello, P.; Bowers, M. D., Cipollini, D., Comparative herbivory rates and specialized metabolite profiles in the leaves of native and non-native Lonicera species Journal of Chemical Ecology, 41 (12), 1069-1079. (available from https://www.researchgate.net/publication/283748739_Comparative_Herbivory_Rates_and_Secondary_Metabolite_Profiles_in_the_Leaves_of_Native_and_Non-Native_Lonicera_Species) Chakraborty, S.; Cai, Y.; Tarr, M.A.; 2014. “In vitro surface mapping of apolipoprotein B-100 in low density lipoprotein using peroxynitrite and hypochlorite” Proteomics, 14 (21-22), 2614-22. (available from https://www.researchgate.net/publication/265171778_In_vitro_oxidative_footprinting_provides_insight_into_apolipoprotein_B-100_structure_in_low_density_lipoprotein) Shen, X.; Chakraborty, S.; Dugas, T.; and Kevil, C. G.; 2014 “Hydrogen sulfide measurement using sulfide dibimane: critical evaluation with electrospray ion trap mass spectrometry” Nitric Oxide, 41, 97-104. (available from https://www.researchgate.net/publication/263130637_Hydrogen_sulfide_measurement_using_sulfide_dibimane_Critical_evaluation_with_electrospray_ion_trap_mass_spectrometry) Chakraborty, S.; Whitehill, J.G.A.; Hill, A.L.; Opiyo, S; Cipollini, D.; Herms, D.A.; Bonello, P.; 2014. “Effects of water availability on emerald ash borer larval performance and phloem phenolics of Manchurian and black ash” Plant Cell and Environment, 37 (4), 1009-21. (available from https://www.researchgate.net/publication/257812829_Effects_of_Water_Availability_on_Emerald_Ash_Borer_Larval_Performance_and_Phloem_Phenolics_of_Manchurian_and_Black_Ash) Villari C, Battisti A, Chakraborty S, Michelozzi M, Bonello P, Faccoli M. 2012. Nutritional and pathogenic fungi associated with the pine engraver beetle trigger comparable defenses in scots pine. Tree Physiol. 32(7), 867-79 (freely available from the publisher's website http://treephys.oxfordjournals.org/content/32/7/867.full) Chakraborty, S.; Cai, Y.; Tarr, M. A., 2010, Mapping oxidations of apolipoprotein B-100 in human low-density lipoprotein by liquid chromatography–tandem mass spectrometry. Anal Biochem404, 109-117. (please send an email to the author for a copy) Chakraborty, S.; Tarr, M.A., 2007, Fluoride detection based on fluorescence enhancement of thioureido naphthalene derivative. Can J Chem85, 153. (available from https://www.researchgate.net/publication/237846481_Fluoride_detection_based_on_fluorescence_enhancement_of_thioureido_naphthalene_derivative)