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研究领域

Research interests: I am a neurophysiologist and my primary research interest is studying how stress (physical or psychological) alters neural activity in the mammalian brain. I am particularly interested in stress-evoked responses in the prefrontal cortex, the hippocampus, amygdala, striatum, and the interactions between these brain structures. This research has important implications for many diseases that are triggered by or exacerbated by stress, including Post-Traumatic Stress Disorder (PTSD), depression, schizophrenia, cardiovascular disease, as well as drug addition and just understanding how the brain works. My experimental techniques include single-unit electrophysiological recording in awake rats, animal behavior, cognitive measures, and pharmacological manipulation of the neuroendocrine system. My work also requires computational modeling of individual neurons and systems of neurons, as well as computational analysis of spike train responses.

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Baeg E, Jackson ME, Jedema, H, & Bradberry CW. 2009. Orbitofrontal and Anterior Cingulate Cortex Neurons Selectively Process Cocaine-Associated Environmental Cues in the Rhesus Monkey. Journal of Neuroscience. 29(37):11619-11627 Jackson ME & Moghaddam B. 2006. Distinct patterns of plasticity in prefrontal cortex neurons that encode slow and fast responses to stress, European Journal of Neuroscience, 24:1702-1710.

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