个人简介
B.S. Tianjin University of Science & Technology, Biochemical Engineering
M.S. Tianjin University of Science & Technology, Fermentation Engineering
Ph.D. Chinese Academy of Sciences, Biochemical Engineering
Postdoctoral Training: University of Kentucky, Lexington, KY
研究领域
Nanoparticle-based drug delivery for improving therapeutic indices of anti-cancer agents
Image-guided drug delivery for optimizing cancer diagnosis and therapy
Neutron-activatable nanoparticles for radiation therapy
近期论文
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Tran TH, Nguyen CT, Gonzalez-Fajardo L, Hargrove D, Song D, Deshmukh P, Mahajan L, Ndaya D, Lai L, Kasi RM, and Lu X. (2014) Long circulating self-assembled nanoparticles from cholesterol-containing brush-like block copolymers for improved drug delivery to tumors. Biomacromolecules., 15 (11): 4363–4375
Tran, T.H., Guo, Y., Song, D., Bruno, R.S., ,Lu, X. (2014) Quercetin-containing self-nanoemulsifying drug delivery system for improving oral bioavailability, Journal of Pharmaceutical Sciences 103 (3), 840–852.
Di Pasqua, A.J., Yuan, H., Chung, Y., Kim, J.K., Huckle, J.E., Li, C., Sadgrove, M., Tran, T.H., Jay, M., Lu, X. (2013) Neutron-activatable holmium-containing mesoporous silica nanoparticles as a potential radionuclide therapeutic agent for ovarian cancer, Journal of Nuclear Medicine 54,111-116.
Kim, J.K., Yuan, H., Nie, J., Yang, Y.T., Leggas, M., Potter, P.M., Rinehart, J., Jay, M. and Lu, X. (2012) High payload dual therapeutic-imaging nanocarriers for triggered tumor delivery, Small 8, 2895-903.
Di Pasqua, A.J., Huckle, J.E., Kim, J.K., Chung, Y., Wang A.Z., Jay, M. and Lu, X. (2012) Preparation of neutron activatable holmium nanoparticles for the treatment of ovarian cancer metastases, Small 8, 997-1000.
Kim, J.K., Howard, M.D., Dziubla, T.D., Rinehart, J., Jay, M. and Lu, X. (2011) Uniformity of drug payload and its effect on stability of solid lipid nanoparticles containing an ester prodrug, ACS Nano 5(1), 209-216.