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B.S. Yale University Biology M.D. University of California San Francisco Medicine

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Consensus computational network analysis for identifying candidate outer membrane proteins from Borrelia spirochetes. Kenedy, Melisha R; Scott, Edgar J; Shrestha, Binu; Anand, Arvind; Iqbal, Henna; Radolf, Justin D; Dyer, David W; Akins, Darrin R BMC microbiology 2016 Jan;16(1):141 Genomic insights into the Ixodes scapularis tick vector of Lyme disease. Gulia-Nuss, Monika; Nuss, Andrew B; Meyer, Jason M; Sonenshine, Daniel E; Roe, R Michael; Waterhouse, Robert M; Sattelle, David B; de la Fuente, José; Ribeiro, Jose M; Megy, Karine; Thimmapuram, Jyothi; Miller, Jason R; Walenz, Brian P; Koren, Sergey; Hostetler, Jessica B; Thiagarajan, Mathangi; Joardar, Vinita S; Hannick, Linda I; Bidwell, Shelby; Hammond, Martin P; Young, Sarah; Zeng, Qiandong; Abrudan, Jenica L; Almeida, Francisca C; Ayllón, Nieves; Bhide, Ketaki; Bissinger, Brooke W; Bonzon-Kulichenko, Elena; Buckingham, Steven D; Caffrey, Daniel R; Caimano, Melissa J; Croset, Vincent; Driscoll, Timothy; Gilbert, Don; Gillespie, Joseph J; Giraldo-Calderón, Gloria I; Grabowski, Jeffrey M; Jiang, David; Khalil, Sayed M S; Kim, Donghun; Kocan, Katherine M; Koci, Juraj; Kuhn, Richard J; Kurtti, Timothy J; Lees, Kristin; Lang, Emma G; Kennedy, Ryan C; Kwon, Hyeogsun; Perera, Rushika; Qi, Yumin; Radolf, Justin D; Sakamoto, Joyce M; Sánchez-Gracia, Alejandro; Severo, Maiara S; Silverman, Neal; ?imo, Ladislav; Tojo, Marta; Tornador, Cristian; Van Zee, Janice P; Vázquez, Jesús; Vieira, Filipe G; Villar, Margarita; Wespiser, Adam R; Yang, Yunlong; Zhu, Jiwei; Arensburger, Peter; Pietrantonio, Patricia V; Barker, Stephen C; Shao, Renfu; Zdobnov, Evgeny M; Hauser, Frank; Grimmelikhuijzen, Cornelis J P; Park, Yoonseong; Rozas, Julio; Benton, Richard; Pedra, Joao H F; Nelson, David R; Unger, Maria F; Tubio, Jose M C; Tu, Zhijian; Robertson, Hugh M; Shumway, Martin; Sutton, Granger; Wortman, Jennifer R; Lawson, Daniel; Wikel, Stephen K; Nene, Vishvanath M; Fraser, Claire M; Collins, Frank H; Birren, Bruce; Nelson, Karen E; Caler, Elisabet; Hill, Catherine A Nature Communications 2016 Jan;710507 Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding. Bauer, William J; Luthra, Amit; Zhu, Guangyu; Radolf, Justin D; Malkowski, Michael G; Caimano, Melissa J Journal of structural biology 2015 Aug;192(1):48-58 Cyclic di-GMP modulates gene expression in Lyme disease spirochetes at the tick-mammal interface to promote spirochete survival during the blood meal and tick-to-mammal transmission. Caimano, Melissa J; Dunham-Ems, Star; Allard, Anna M; Cassera, Maria B; Kenedy, Melisha; Radolf, Justin D Infection and immunity 2015 May;83(8):3043-60 A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326. Luthra, Amit; Anand, Arvind; Hawley, Kelly L; LeDoyt, Morgan; La Vake, Carson J; Caimano, Melissa J; Cruz, Adriana R; Salazar, Juan C; Radolf, Justin D Journal of bacteriology 2015 Mar;197(11):1906-20 Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL β-BARREL DOMAIN. Anand, Arvind; LeDoyt, Morgan; Karanian, Carson; Luthra, Amit; Koszelak-Rosenblum, Mary; Malkowski, Michael G; Puthenveetil, Robbins; Vinogradova, Olga; Radolf, Justin D The Journal of biological chemistry 2015 Mar;290(19):12313-31 A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the serofast state after therapy. Se?a, Arlene C; Zhang, Xiao-Hui; Li, Trudy; Zheng, He-Ping; Yang, Bin; Yang, Li-Gang; Salazar, Juan C; Cohen, Myron S; Moody, M Anthony; Radolf, Justin D; Tucker, Joseph D BMC infectious diseases 2015 Jan;15479 Correction for Anand et al., The Major Outer Sheath Protein (Msp) of Treponema denticola Has a Bipartite Domain Architecture and Exists as Periplasmic and Outer Membrane-Spanning Conformers. Anand, Arvind; Luthra, Amit; Edmond, Maxwell E; LeDoyt, Morgan; Caimano, Melissa J; Radolf, Justin D Journal of bacteriology 2014 Sep;196(18):3361 Correction for Anand et al., TprC/D (Tp0117/131), a Trimeric, Pore-Forming Rare Outer Membrane Protein of Treponema pallidum, Has a Bipartite Domain Structure. Anand, Arvind; Luthra, Amit; Dunham-Ems, Star; Caimano, Melissa J; Karanian, Carson; LeDoyt, Morgan; Cruz, Adriana R; Salazar, Juan C; Radolf, Justin D Journal of bacteriology 2014 Sep;196(18):3360 HrpA, an RNA helicase involved in RNA processing, is required for mouse infectivity and tick transmission of the Lyme disease spirochete. Salman-Dilgimen, Aydan; Hardy, Pierre-Olivier; Radolf, Justin D; Caimano, Melissa J; Chaconas, George PLoS pathogens 2013 Dec;9(12):e1003841 Characterization of outer membranes isolated from Treponema pallidum, the syphilis spirochete. Radolf, J D; Robinson, E J; Bourell, K W; Akins, D R; Porcella, S F; Weigel, L M; Jones, J D; Norgard, M V Infection and immunity 2013 Nov;63(11):4244-52 TP0453, a concealed outer membrane protein of Treponema pallidum, enhances membrane permeability. Hazlett, Karsten R O; Cox, David L; Decaffmeyer, Marc; Bennett, Michael P; Desrosiers, Daniel C; La Vake, Carson J; La Vake, Morgan E; Bourell, Kenneth W; Robinson, Esther J; Brasseur, Robert; Radolf, Justin D Journal of bacteriology 2013 Sep;187(18):6499-508 The major outer sheath protein (Msp) of Treponema denticola has a bipartite domain architecture and exists as periplasmic and outer membrane-spanning conformers. Anand, Arvind; Luthra, Amit; Edmond, Maxwell E; Ledoyt, Morgan; Caimano, Melissa J; Radolf, Justin D Journal of bacteriology 2013 May;195(9):2060-71 Pulling the trigger on lyme arthritis. Radolf, Justin D The Journal of infectious diseases 2013 Mar;207(6):877-9

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