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B.A. Reed College Biology Ph.D. Tufts University Molecular Biology and Microbiology

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Iron addiction: a novel therapeutic target in ovarian cancer. Basuli, D; Tesfay, L; Deng, Z; Paul, B; Yamamoto, Y; Ning, G; Xian, W; McKeon, F; Lynch, M; Crum, C P; Hegde, P; Brewer, M; Wang, X; Miller, L D; Dyment, N; Torti, F M; Torti, S V Oncogene 2017 Mar; DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms. Lemler, David J; Lynch, Miranda L; Tesfay, Lia; Deng, Zhiyong; Paul, Bibbin T; Wang, Xiaohong; Hegde, Poornima; Manz, David H; Torti, Suzy V; Torti, Frank M Breast cancer research : BCR 2017 Mar;19(1):25 Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective. Chifman, Julia; Arat, Seda; Deng, Zhiyong; Lemler, Erica; Pino, James C; Harris, Leonard A; Kochen, Michael A; Lopez, Carlos F; Akman, Steven A; Torti, Frank M; Torti, Suzy V; Laubenbacher, Reinhard PLoS computational biology 2017 Feb;13(2):e1005352 Mitochondria and Iron: current questions. Paul, Bibbin T; Manz, David H; Torti, Frank M; Torti, Suzy V Expert review of hematology 2017 Jan;10(1):65-79 Iron and cancer: recent insights. Manz, David H; Blanchette, Nicole L; Paul, Bibbin T; Torti, Frank M; Torti, Suzy V Annals of the New York Academy of Sciences 2016 Feb; Modulation of hepcidin to treat iron deregulation: potential clinical applications. Blanchette, Nicole L; Manz, David H; Torti, Frank M; Torti, Suzy V Expert review of hematology 2015 Dec;1-18 In Vitro and In Vivo Correlates of Physiologic and Neoplastic Human Fallopian Tube Stem Cells. Yamamoto, Yusuke; Ning, Gang; Howitt, Brooke E; Mehra, Karishma; Wu, Lingyan; Wang, Xia; Hong, Yue; Kern, Florian; Wei, Tay Seok; Zhang, Ting; Nagarajan, Niranjan; Basuli, Debargha; Torti, Suzy; Brewer, Molly; Choolani, Mahesh; McKeon, Frank; Crum, Christopher P; Xian, Wa The Journal of pathology 2015 Sep; Targeting breast cancer with sugar-coated carbon nanotubes. Fahrenholtz, Cale D; Hadimani, Mallinath; King, S Bruce; Torti, Suzy V; Singh, Ravi Nanomedicine (London, England) 2015 Aug;10(16):2481-97 Yet another function of p53--the switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: implications for autophagy inhibition as a therapeutic strategy. Chakradeo, Shweta; Sharma, Khushboo; Alhaddad, Aisha; Bakhshwin, Duaa; Le, Ngoc; Harada, Hisashi; Nakajima, Wataru; Yeudall, W Andrew; Torti, Suzy V; Torti, Frank M; Gewirtz, David A Molecular pharmacology 2015 May;87(5):803-14 Hepcidin regulation in prostate and its disruption in prostate cancer. Tesfay, Lia; Clausen, Kathryn A; Kim, Jin Woo; Hegde, Poornima; Wang, Xiaohong; Miller, Lance D; Deng, Zhiyong; Blanchette, Nicole; Arvedson, Tara; Miranti, Cindy K; Babitt, Jodie L; Lin, Herbert Y; Peehl, Donna M; Torti, Frank M; Torti, Suzy V Cancer research 2015 Apr;75(11):2254-63 IRP2 regulates breast tumor growth. Wang, Wei; Deng, Zhiyong; Hatcher, Heather; Miller, Lance D; Di, Xiumin; Tesfay, Lia; Sui, Guangchao; D'Agostino, Ralph B; Torti, Frank M; Torti, Suzy V Cancer research 2014 Jan;74(2):497-507 Epidemiological associations between iron and cardiovascular disease and diabetes. Basuli, Debargha; Stevens, Richard G; Torti, Frank M; Torti, Suzy V Frontiers in pharmacology 2014 Jan;5117 Ferritin H is a novel marker of early erythroid precursors and macrophages. Wang, Wei; Grier, David D; Woo, Jennifer; Ward, Martha; Sui, Guangchao; Torti, Suzy V; Torti, Frank M; Beaty, Michael W Histopathology 2013 May;62(6):931-40 Iron and cancer: more ore to be mined. Torti, Suzy V; Torti, Frank M Nature reviews. Cancer 2013 May;13(5):342-55 Spatial and temporal measurements of temperature and cell viability in response to nanoparticle-mediated photothermal therapy. Whitney, Jon R; Rodgers, Amanda; Harvie, Erica; Carswell, William F; Torti, Suzy; Puretzky, Alex A; Rouleau, Christopher M; Geohegan, David B; Rylander, Christopher G; Rylander, Marissa N Nanomedicine (London, England) 2012 Nov;7(11):1729-42 Heat localization for targeted tumor treatment with nanoscale near-infrared radiation absorbers. Xie, Bin; Singh, Ravi; Torti, F M; Keblinski, Pawel; Torti, Suzy Physics in medicine and biology 2012 Sep;57(18):5765-75 Hybrid 2D nanomaterials as dual-mode contrast agents in cellular imaging. Narayanan, Tharangattu N; Gupta, Bipin K; Vithayathil, Sajna A; Aburto, Rebeca R; Mani, Sendurai A; Taha-Tijerina, Jaime; Xie, Bin; Kaipparettu, Benny A; Torti, Suzy V; Ajayan, Pulickel M Advanced materials (Deerfield Beach, Fla.) 2012 Jun;24(22):2992-8 The core control system of intracellular iron homeostasis: a mathematical model. Chifman, J; Kniss, A; Neupane, P; Williams, I; Leung, B; Deng, Z; Mendes, P; Hower, V; Torti, F M; Akman, S A; Torti, S V; Laubenbacher, R Journal of theoretical biology 2012 May;30091-9 Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27. Wan, Meimei; Huang, Weiwei; Kute, Timothy E; Miller, Lance D; Zhang, Qiang; Hatcher, Heather; Wang, Jingxuan; Stovall, Daniel B; Russell, Gregory B; Cao, Paul D; Deng, Zhiyong; Wang, Wei; Zhang, Qingyuan; Lei, Ming; Torti, Suzy V; Akman, Steven A; Sui, Guangchao The American journal of pathology 2012 May;180(5):2120-33 The resistance of breast cancer stem cells to conventional hyperthermia and their sensitivity to nanoparticle-mediated photothermal therapy. Burke, Andrew R; Singh, Ravi N; Carroll, David L; Wood, James C S; D'Agostino, Ralph B; Ajayan, Pulickel M; Torti, Frank M; Torti, Suzy V Biomaterials 2012 Apr;33(10):2961-70 Ferritin blocks inhibitory effects of two-chain high molecular weight kininogen (HKa) on adhesion and survival signaling in endothelial cells. Tesfay, Lia; Huhn, Annissa J; Hatcher, Heather; Torti, Frank M; Torti, Suzy V PloS one 2012 Jan;7(7):e40030 An iron regulatory gene signature predicts outcome in breast cancer. Miller, Lance D; Coffman, Lan G; Chou, Jeff W; Black, Michael A; Bergh, Jonas; D'Agostino, Ralph; Torti, Suzy V; Torti, Frank M Cancer research 2011 Nov;71(21):6728-37 Development of iron-containing multiwalled carbon nanotubes for MR-guided laser-induced thermotherapy. Ding, Xuanfeng; Singh, Ravi; Burke, Andrew; Hatcher, Heather; Olson, John; Kraft, Robert A; Schmid, Michael; Carroll, David; Bourland, J Daniel; Akman, Steven; Torti, Frank M; Torti, Suzy V Nanomedicine (London, England) 2011 Oct;6(8):1341-52 SOSTDC1 differentially modulates Smad and beta-catenin activation and is down-regulated in breast cancer. Clausen, Kathryn A; Blish, Kimberly R; Birse, Charles E; Triplette, Matthew A; Kute, Timothy E; Russell, Gregory B; D'Agostino, Ralph B; Miller, Lance D; Torti, Frank M; Torti, Suzy V Breast cancer research and treatment 2011 Oct;129(3):737-46 Bioinformatics tools for cancer metabolomics. Blekherman, Grigoriy; Laubenbacher, Reinhard; Cortes, Diego F; Mendes, Pedro; Torti, Frank M; Akman, Steven; Torti, Suzy V; Shulaev, Vladimir Metabolomics : Official journal of the Metabolomic Society 2011 Sep;7(3):329-343

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