Klobutcher, Lawrence - University of Connecticut - Department of Molecular Biology and Biophysics

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B.S. Loyola University Biology M.Phil. Yale University Human Genetics Ph.D. Yale University Human Genetics

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Position-dependent termination and widespread obligatory frameshifting in Euplotes translation. Lobanov, Alexei V; Heaphy, Stephen M; Turanov, Anton A; Gerashchenko, Maxim V; Pucciarelli, Sandra; Devaraj, Raghul R; Xie, Fang; Petyuk, Vladislav A; Smith, Richard D; Klobutcher, Lawrence A; Atkins, John F; Miceli, Cristina; Hatfield, Dolph L; Baranov, Pavel V; Gladyshev, Vadim N Nature structural & molecular biology 2016 Nov; Vacuolar protein sorting protein 13A, TtVPS13A, localizes to the tetrahymena thermophila phagosome membrane and is required for efficient phagocytosis. Samaranayake, Haresha S; Cowan, Ann E; Klobutcher, Lawrence A Eukaryotic cell 2011 Sep;10(9):1207-18 In memoriam: David Marshall Prescott (1926-2011). Klobutcher, Lawrence A The Journal of eukaryotic microbiology 2011 Jan;58(4):394-6 Genetic code supports targeted insertion of two amino acids by one codon. Turanov, Anton A; Lobanov, Alexey V; Fomenko, Dmitri E; Morrison, Hilary G; Sogin, Mitchell L; Klobutcher, Lawrence A; Hatfield, Dolph L; Gladyshev, Vadim N Science (New York, N.Y.) 2009 Jan;323(5911):259-61 The Tetrahymena thermophila phagosome proteome. Jacobs, Mary Ellen; DeSouza, Leroi V; Samaranayake, Haresha; Pearlman, Ronald E; Siu, K W Michael; Klobutcher, Lawrence A Eukaryotic cell 2006 Dec;5(12):1990-2000 The Bacillus subtilis spore coat provides "eat resistance" during phagocytic predation by the protozoan Tetrahymena thermophila. Klobutcher, Lawrence A; Ragkousi, Katerina; Setlow, Peter Proceedings of the National Academy of Sciences of the United States of America 2006 Jan;103(1):165-70 Distinct paths to stop codon reassignment by the variant-code organisms Tetrahymena and Euplotes. Salas-Marco, Joe; Fan-Minogue, Hua; Kallmeyer, Adam K; Klobutcher, Lawrence A; Farabaugh, Philip J; Bedwell, David M Molecular and cellular biology 2006 Jan;26(2):438-47 Sequencing of random Euplotes crassus macronuclear genes supports a high frequency of +1 translational frameshifting. Klobutcher, Lawrence A Eukaryotic cell 2005 Dec;4(12):2098-105 Evolution of programmed ribosomal frameshifting in the TERT genes of Euplotes. M?llenbeck, Matthias; Gavin, Michael C; Klobutcher, Lawrence A Journal of molecular evolution 2004 Jun;58(6):701-11 Assessing the effectiveness of coding and non-coding regions in antisense ribosome inhibition of gene expression in Tetrahymena. Jacobs, Mary Ellen; Cortezzo, Donnamarie E; Klobutcher, Lawrence A The Journal of eukaryotic microbiology 2004 Jan;51(5):536-41 Tec3, a new developmentally eliminated DNA element in Euplotes crassus. Jacobs, Mary Ellen; Sánchez-Blanco, Adolfo; Katz, Laura A; Klobutcher, Lawrence A Eukaryotic cell 2003 Feb;2(1):103-14 De novo telomere addition to spacer sequences prior to their developmental degradation in Euplotes crassus. M?llenbeck, Matthias; Klobutcher, Lawrence A Nucleic acids research 2002 Jan;30(2):523-31 Genome remodeling in ciliated protozoa. Jahn, Carolyn L; Klobutcher, Lawrence A Annual review of microbiology 2002 Jan;56489-520 The Euplotes crassus conjugation-specific conN1 gene encodes a transcription elongation factor TFIIS-like protein. Ghosh, S; Barrett, D M; Klobutcher, L A The Journal of eukaryotic microbiology 2001 Jan;48(2):218-20 A development-specific histone H3 localizes to the developing macronucleus of Euplotes. Ghosh, S; Klobutcher, L A Genesis (New York, N.Y. : 2000) 2000 Mar;26(3):179-88 conZA8 encodes an abundant protein targeted to the developing macronucleus in Euplotes crassus. Jacobs, M E; Ling, Z; Klobutcher, L A The Journal of eukaryotic microbiology 2000 Jan;47(2):105-15 Characterization of in vivo developmental chromosome fragmentation intermediates in E. crassus. Klobutcher, L A Molecular cell 1999 Nov;4(5):695-704 Conserved DNA sequences adjacent to chromosome fragmentation and telomere addition sites in Euplotes crassus. Klobutcher, L A; Gygax, S E; Podoloff, J D; Vermeesch, J R; Price, C M; Tebeau, C M; Jahn, C L Nucleic acids research 1998 Sep;26(18):4230-40 An unusual histone H3 specific for early macronuclear development in Euplotes crassus. Jahn, C L; Ling, Z; Tebeau, C M; Klobutcher, L A Proceedings of the National Academy of Sciences of the United States of America 1997 Feb;94(4):1332-7 Conjugation-specific genes in the ciliate Euplotes crassus: gene expression from the old macronucleus. Ling, Z; Ghosh, S; Jacobs, M E; Klobutcher, L A The Journal of eukaryotic microbiology 1997 Jan;44(1):1-11 Micronuclear and macronuclear sequences of a Euplotes crassus gene encoding a putative nuclear protein kinase. Hale, C A; Jacobs, M E; Estes, H G; Ghosh, S; Klobutcher, L A The Journal of eukaryotic microbiology 1996 Jan;43(5):389-92 Genetic code deviations in the ciliates: evidence for multiple and independent events. Tourancheau, A B; Tsao, N; Klobutcher, L A; Pearlman, R E; Adoutte, A The EMBO journal 1995 Jul;14(13):3262-7 Consensus inverted terminal repeat sequence of Paramecium IESs: resemblance to termini of Tc1-related and Euplotes Tec transposons. Klobutcher, L A; Herrick, G Nucleic acids research 1995 Jun;23(11):2006-13 Developmentally excised DNA sequences in Euplotes crassus capable of forming G quartets. Klobutcher, L A Proceedings of the National Academy of Sciences of the United States of America 1995 Mar;92(6):1979-83 Telomeric repeat sequences are not associated with Tec1 elements in Euplotes crassus. Knecht, K., and Klobutcher, L.A. Eur. J. Protistol. 1995 Jan;31201-207