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B.S. SMU Geology Ph.D. Yale University Geophysics M.D. Yale University School of Medicine Medicine

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Spontaneous Glutamatergic Synaptic Activity Regulates Constitutive COX-2 Expression in Neurons: Opposing roles for the transcription factors CREB and Sp1. Hewett, Sandra J; Shi, Jingxue; Gong, Yifan; Dhandapani, Krishnan; Pilbeam, Carol; Hewett, James A The Journal of biological chemistry 2016 Nov; Prostaglandin-mediated inhibition of PTH-stimulated β-catenin signaling in osteoblasts by bone marrow macrophages. Estus, Thomas L; Choudhary, Shilpa; Pilbeam, Carol C Bone 2016 Feb;85123-130 Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-Stimulated cAMP Signaling in Murine Osteoblasts. Choudhary, Shilpa; Goetjen, Alexandra; Estus, Thomas; Jacome-Galarza, Christian E; Aguila, Hector L; Lorenzo, Joseph; Pilbeam, Carol The Journal of biological chemistry 2015 Dec; Increased expression of L-selectin (CD62L) in high-grade urothelial carcinoma: A potential marker for metastatic disease. Choudhary, Dharamainder; Hegde, Poornima; Voznesensky, Olga; Choudhary, Shilpa; Kopsiaftis, Stavros; Claffey, Kevin P; Pilbeam, Carol C; Taylor, John A Urologic oncology 2015 Jan;33(9):387.e17-27 Cyclooxygenase-2 suppresses the anabolic response to PTH infusion in mice. Choudhary, Shilpa; Canalis, Ernesto; Estus, Thomas; Adams, Douglas; Pilbeam, Carol PloS one 2015 Jan;10(3):e0120164 Randomized double-blind placebo-controlled trial of celecoxib for oral mucositis in patients receiving radiation therapy for head and neck cancer. Lalla, Rajesh V; Choquette, Linda E; Curley, Kathleen F; Dowsett, Robert J; Feinn, Richard S; Hegde, Upendra P; Pilbeam, Carol C; Salner, Andrew L; Sonis, Stephen T; Peterson, Douglas E Oral oncology 2014 Aug;50(11):1098-103 Prostaglandin E2 acts via bone marrow macrophages to block PTH-stimulated osteoblast differentiation in vitro. Choudhary, Shilpa; Blackwell, Katherine; Voznesensky, Olga; Deb Roy, Abhijit; Pilbeam, Carol Bone 2013 Sep;56(1):31-41 Macrophage migratory inhibitory factor promotes bladder cancer progression via increasing proliferation and angiogenesis. Choudhary, Shilpa; Hegde, Poornima; Pruitt, James R; Sielecki, Thais M; Choudhary, Dharamainder; Scarpato, Kristen; Degraff, David J; Pilbeam, Carol C; Taylor, John A Carcinogenesis 2013 Aug;34(12):2891-9 Basal bone phenotype and increased anabolic responses to intermittent parathyroid hormone in healthy male COX-2 knockout mice. Xu, Manshan; Choudhary, Shilpa; Voznesensky, Olga; Gao, Qi; Adams, Douglas; Diaz-Doran, Vilmaris; Wu, Qian; Goltzman, David; Raisz, Lawrence G; Pilbeam, Carol C Bone 2010 Aug;47(2):341-52 Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: role of the calcium-calcineurin-NFAT pathway. Huang, Hechang; Chikazu, Daichi; Voznesensky, Olga S; Herschman, Harvey R; Kream, Barbara E; Drissi, Hicham; Pilbeam, Carol C Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010 Apr;25(4):819-29 Role of the cyclooxygenase pathway in chemotherapy-induced oral mucositis: a pilot study. Lalla, Rajesh V; Pilbeam, Carol C; Walsh, Stephen J; Sonis, Stephen T; Keefe, Dorothy M K; Peterson, Douglas E Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2010 Jan;18(1):95-103 Neuropeptide Y is expressed by osteocytes and can inhibit osteoblastic activity. Igwe, John C; Jiang, Xi; Paic, Frane; Ma, Li; Adams, Douglas J; Baldock, Paul A; Pilbeam, Carol C; Kalajzic, Ivo Journal of cellular biochemistry 2009 Oct;108(3):621-30 Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice. Gao, Qi; Zhan, Peili; Alander, Cynthia B; Kream, Barbara E; Hao, Chuanming; Breyer, Matthew D; Pilbeam, Carol C; Raisz, Lawrence G Bone 2009 Jul;45(1):98-103 Effects of prostaglandin E2 on bone in mice in vivo. Gao, Qi; Xu, Manshan; Alander, Cynthia B; Choudhary, Shilpa; Pilbeam, Carol C; Raisz, Lawrence G Prostaglandins & other lipid mediators 2009 Jun;89(1-2):20-5 Bone morphogenetic protein 2 enhances PGE2-stimulated osteoclast formation in murine bone marrow cultures Blackwell K.A., Hortschansky P., Sanovic S., Choudhary S., Raisz L.G., Pilbeam C.C. Prostaglandins and Other Lipid Mediators 2009 Jan;90(40241):76-80 Effects of Prostaglandin E2 on bone in mice in vivo. Gao Q, Xu M, Alander CB, Choudhary S, Pilbeam CC, and Raisz LG. Prostaglandins Other Lipid Mediat 2009 Jan;8920-25 Regulation of the prostaglandin pathway during development of invasive bladder cancer in mice. Taylor, John A; Ristau, Benjamin; Bonnemaison, Mathilde; Voznesensky, Olga S; Hegde, Poornima; Kuchel, George A; Pilbeam, Carol C Prostaglandins & other lipid mediators 2009 Jan;88(1-2):36-41 Anabolic effects of PTH in cyclooxygenase-2 knockout osteoblasts in vitro. Choudhary, Shilpa; Huang, Hechang; Raisz, Lawrence; Pilbeam, Carol Biochemical and biophysical research communications 2008 Aug;372(4):536-41 Effect of deletion of the prostaglandin EP2 receptor on the anabolic response to prostaglandin E2 and a selective EP2 receptor agonist. Choudhary, Shilpa; Alander, Cynthia; Zhan, Peili; Gao, Qi; Pilbeam, Carol; Raisz, Lawrence Prostaglandins & other lipid mediators 2008 Jun;86(1-4):35-40 Effect of MKP-1 deletion on the fluid shear stress induction of COX-2 expression in osteoblasts. Ma L, Mehrotra M, Choudhary S, Raisz L, Pilbeam C. J Bone Miner Res 2008 Jan;23S234 Measurement of muscle disease by quantitative second-harmonic generation imaging. Plotnikov, Sergey V; Kenny, Anne M; Walsh, Stephen J; Zubrowski, Beata; Joseph, Cherian; Scranton, Victoria L; Kuchel, George A; Dauser, Deborah; Xu, Manshan; Pilbeam, Carol C; Adams, Douglas J; Dougherty, Robert P; Campagnola, Paul J; Mohler, William A Journal of biomedical optics 2008 Jan;13(4):044018 Cyclooxygenase-2 gene disruption promotes proliferation of murine calvarial osteoblasts in vitro. Xu, Zheng; Choudhary, Shilpa; Okada, Yosuke; Voznesensky, Olga; Alander, Cynthia; Raisz, Lawrence; Pilbeam, Carol Bone 2007 Jul;41(1):68-76 Strontium ranelate promotes osteoblastic differentiation and mineralization of murine bone marrow stromal cells: involvement of prostaglandins. Choudhary, Shilpa; Halbout, Philippe; Alander, Cynthia; Raisz, Lawrence; Pilbeam, Carol Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007 Jul;22(7):1002-10 Effects of prostaglandin E2 and lipopolysaccharide on osteoclastogenesis in RAW 264.7 cells. Kaneko, H; Mehrotra, M; Alander, C; Lerner, U; Pilbeam, C; Raisz, L Prostaglandins, leukotrienes, and essential fatty acids 2007 Jan;77(3-4):181-6 Null mutation in macrophage migration inhibitory factor prevents muscle cell loss and fibrosis in partial bladder outlet obstruction. Taylor, John A; Zhu, Qing; Irwin, Brian; Maghaydah, Yazeed; Tsimikas, John; Pilbeam, Carol; Leng, Lin; Bucala, Richard; Kuchel, George A American journal of physiology. Renal physiology 2006 Dec;291(6):F1343-53 Fluid flow induces Rankl expression in primary murine calvarial osteoblasts. Mehrotra, Meenal; Saegusa, Masatomo; Wadhwa, Sunil; Voznesensky, Olga; Peterson, Donald; Pilbeam, Carol Journal of cellular biochemistry 2006 Aug;98(5):1271-83

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