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B.S. Rensselaer Polytechnic Institute Physics M.D. State University of New York, Downstate Medical Center Medicine

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Runx1 regulates myeloid precursor differentiation into osteoclasts without affecting differentiation into antigen presenting or phagocytic cells in both males and females.Paglia, David N; Yang, Xiaochuan; Kalinowski, Judith; Jastrzebski, Sandra; Drissi, Hicham; Lorenzo, Joseph Endocrinology 2016 Jun;en20152037 Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-Stimulated cAMP Signaling in Murine Osteoblasts.Choudhary, Shilpa; Goetjen, Alexandra; Estus, Thomas; Jacome-Galarza, Christian E; Aguila, Hector L; Lorenzo, Joseph; Pilbeam, Carol The Journal of biological chemistry 2015 Dec; Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.Adapala, Naga Suresh; Holland, Danielle; Scanlon, Vanessa; Barbe, Mary F; Langdon, Wallace Y; Tsygankov, Alexander Y; Lorenzo, Joseph A; Sanjay, Archana Bone 2014 Jul;671-9 Runx1-mediated regulation of osteoclast differentiation and function.Soung, Do Y; Kalinowski, Judith; Baniwal, Sanjeev K; Jacome-Galarza, Christian E; Frenkel, Baruch; Lorenzo, Joseph; Drissi, Hicham Molecular endocrinology (Baltimore, Md.) 2014 Apr;28(4):546-53 Altered hematopoietic stem cell and osteoclast precursor frequency in cathepsin K null mice.Jacome-Galarza, Christian; Soung, Do Yu; Adapala, Naga Suresh; Pickarski, Maureen; Sanjay, Archana; Duong, Le T; Lorenzo, Joseph A; Drissi, Hicham Journal of cellular biochemistry 2014 Mar;115(8):1449-57 Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b.Adapala, Naga Suresh; Barbe, Mary F; Tsygankov, Alexander Y; Lorenzo, Joseph A; Sanjay, Archana Journal of cellular biochemistry 2014 Jan;115(7):1277-89 Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery.Jacome-Galarza, Christian E; Lee, Sun-Kyeong; Lorenzo, Joseph A; Aguila, Hector Leonardo Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 May;28(5):1203-13 Changes in bone sclerostin levels in mice after ovariectomy vary independently of changes in serum sclerostin levels.Jastrzebski, Sandra; Kalinowski, Judith; Stolina, Marina; Mirza, Faryal; Torreggiani, Elena; Kalajzic, Ivo; Won, Hee Yeon; Lee, Sun-Kyeong; Lorenzo, Joseph Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Mar;28(3):618-26 Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling.Park-Min, Kyung-Hyun; Lee, Eun Young; Moskowitz, Neal K; Lim, Elisha; Lee, Sun-Kyeong; Lorenzo, Joseph A; Huang, Chuanxin; Melnick, Ari M; Purdue, P Edward; Goldring, Steven R; Ivashkiv, Lionel B Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Jan;28(1):135-49 Osteoblast-specific overexpression of human interleukin-7 rescues the bone mass phenotype of interleukin-7-deficient female mice.Aguila, Hector L; Mun, Se Hwan; Kalinowski, Judith; Adams, Douglas J; Lorenzo, Joseph A; Lee, Sun-Kyeong Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012 May;27(5):1030-42 Long-term treatment with raloxifene, but not bisphosphonates, reduces circulating sclerostin levels in postmenopausal women.Chung, Y E; Lee, S H; Lee, S-Y; Kim, S-Y; Kim, H-H; Mirza, F S; Lee, S-K; Lorenzo, J A; Kim, G S; Koh, J-M Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2012 Apr;23(4):1235-43 Parathyroid hormone regulates the distribution and osteoclastogenic potential of hematopoietic progenitors in the bone marrow.Jacome-Galarza, Christian E; Lee, Sun-Kyeong; Lorenzo, Joseph A; Aguila, Hector Leonardo Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011 Jun;26(6):1207-16 How B cells influence bone biology in health and disease.Horowitz, Mark C; Fretz, Jackie A; Lorenzo, Joseph A Bone 2010 Sep;47(3):472-9 Immature osteoblast lineage cells increase osteoclastogenesis in osteogenesis imperfecta murine.Li, Haitao; Jiang, Xi; Delaney, John; Franceschetti, Tiziana; Bilic-Curcic, Ines; Kalinovsky, Judy; Lorenzo, Joseph A; Grcevic, Danka; Rowe, David W; Kalajzic, Ivo The American journal of pathology 2010 May;176(5):2405-13 Serum sclerostin levels negatively correlate with parathyroid hormone levels and free estrogen index in postmenopausal women.Mirza, Faryal S; Padhi, I Desmond; Raisz, Lawrence G; Lorenzo, Joseph A The Journal of clinical endocrinology and metabolism 2010 Apr;95(4):1991-7 Nuclear isoforms of fibroblast growth factor 2 are novel inducers of hypophosphatemia via modulation of FGF23 and KLOTHO.Xiao, Liping; Naganawa, Takahiro; Lorenzo, Joseph; Carpenter, Thomas O; Coffin, J Douglas; Hurley, Marja M The Journal of biological chemistry 2010 Jan;285(4):2834-46 Ebf1-dependent control of the osteoblast and adipocyte lineages.Hesslein, David G T; Fretz, Jackie A; Xi, Yougen; Nelson, Tracy; Zhou, Shoaming; Lorenzo, Joseph A; Schatz, David G; Horowitz, Mark C Bone 2009 Apr;44(4):537-46 Accentuated osteoclastic response to parathyroid hormone undermines bone mass acquisition in osteonectin-null mice.Machado do Reis, Luciene; Kessler, Catherine B; Adams, Douglas J; Lorenzo, Joseph; Jorgetti, Vanda; Delany, Anne M Bone 2008 Aug;43(2):264-73 Estradiol rapidly inhibits osteoclastogenesis and RANKL expression in bone marrow cultures in postmenopausal women: a pilot study.Taxel, P; Kaneko, H; Lee, S-K; Aguila, H L; Raisz, L G; Lorenzo, J A Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2008 Feb;19(2):193-9 v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation.Lee, Seoung-Hoon; Rho, Jaerang; Jeong, Daewon; Sul, Jai-Yoon; Kim, Taesoo; Kim, Nacksung; Kang, Ju-Seob; Miyamoto, Takeshi; Suda, Toshio; Lee, Sun-Kyeong; Pignolo, Robert J; Koczon-Jaremko, Boguslawa; Lorenzo, Joseph; Choi, Yongwon Nature medicine 2006 Dec;12(12):1403-9 Megakaryocyte-mediated inhibition of osteoclast development.Kacena, Melissa A; Nelson, Tracy; Clough, Mary E; Lee, Sun-Kyeong; Lorenzo, Joseph A; Gundberg, Caren M; Horowitz, Mark C Bone 2006 Nov;39(5):991-9 T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy.Lee, Sun-Kyeong; Kadono, Yuho; Okada, Fumihiko; Jacquin, Claire; Koczon-Jaremko, Boguslawa; Gronowicz, Gloria; Adams, Douglas J; Aguila, Hector L; Choi, Yongwon; Lorenzo, Joseph A Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006 Nov;21(11):1704-12 Congenic mice provide in vivo evidence for a genetic locus that modulates serum insulin-like growth factor-I and bone acquisition.Delahunty, K M; Shultz, K L; Gronowicz, G A; Koczon-Jaremko, B; Adamo, M L; Horton, L G; Lorenzo, J; Donahue, L R; Ackert-Bicknell, C; Kream, B E; Beamer, W G; Rosen, C J Endocrinology 2006 Aug;147(8):3915-23 Interleukin-7 influences osteoclast function in vivo but is not a critical factor in ovariectomy-induced bone loss.Lee, Sun-Kyeong; Kalinowski, Judith F; Jacquin, Claire; Adams, Douglas J; Gronowicz, Gloria; Lorenzo, Joseph A Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006 May;21(5):695-702

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