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B.A. Mount Holyoke College Chemistry Ph.D. Yale University Mol Biophys & Biochem

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Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model.Minas, Tsion Zewdu; Surdez, Didier; Javaheri, Tahereh; Tanaka, Miwa; Howarth, Michelle; Kang, Hong-Jun; Han, Jenny; Han, Zhi-Yan; Sax, Barbara; Kream, Barbara E; Hong, Sung-Hyeok; ?elik, Haydar; Tirode, Franck; Tuckermann, Jan; Toretsky, Jeffrey A; Kenner, Lukas; Kovar, Heinrich; Lee, Sean; Sweet-Cordero, E Alejandro; Nakamura, Takuro; Moriggl, Richard; Delattre, Olivier; üren, Aykut Oncotarget 2016 May; Insulin-Like Growth Factor I Does Not Drive New Bone Formation in Experimental Arthritis.van Tok, Melissa N; Yeremenko, Nataliya G; Teitsma, Christine A; Kream, Barbara E; Knaup, Véronique L; Lories, Rik J; Baeten, Dominique L; van Duivenvoorde, Leonie M PloS one 2016 Jan;11(10):e0163632 Impact of targeted PPARγ disruption on bone remodeling.Cao, Jay; Ou, Guomin; Yang, Nianlan; Ding, Kehong; Kream, Barbara E; Hamrick, Mark W; Isales, Carlos M; Shi, Xing-Ming Molecular and cellular endocrinology 2015 Feb;41027-34 Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac.Vang, Amanda G; Housley, William; Dong, Hongli; Basole, Chaitali; Ben-Sasson, Shlomo Z; Kream, Barbara E; Epstein, Paul M; Clark, Robert B; Brocke, Stefan The Biochemical journal 2013 Dec;456(3):463-73 GSK-3β function in bone regulates skeletal development, whole-body metabolism, and male life span.Gillespie, J R; Bush, J R; Bell, G I; Aubrey, L A; Dupuis, H; Ferron, M; Kream, B; DiMattia, G; Patel, S; Woodgett, J R; Karsenty, G; Hess, D A; Beier, F Endocrinology 2013 Oct;154(10):3702-18 Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells.Yang, Wuchen; Guo, Dayong; Harris, Marie A; Cui, Yong; Gluhak-Heinrich, Jelica; Wu, Junjie; Chen, Xiao-Dong; Skinner, Charles; Nyman, Jeffry S; Edwards, James R; Mundy, Gregory R; Lichtler, Alex; Kream, Barbara E; Rowe, David W; Kalajzic, Ivo; David, Val; Quarles, Darryl L; Villareal, Demetri; Scott, Greg; Ray, Manas; Liu, S; Martin, James F; Mishina, Yuji; Harris, Stephen E Journal of cell science 2013 Sep;126(Pt 18):4085-98 Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop.Khosla, Sundeep; Bellido, Teresita M; Drezner, Marc K; Gordon, Catherine M; Harris, Tamara B; Kiel, Douglas P; Kream, Barbara E; LeBoff, Meryl S; Lian, Jane B; Peterson, Charlotte A; Rosen, Clifford J; Williams, John P; Winer, Karen K; Sherman, Sherry S Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011 Nov;26(11):2565-78 Selective osteoblast overexpression of IGF-I in mice prevents low protein-induced deterioration of bone strength and material level properties.Brennan-Speranza, Tara C; Rizzoli, René; Kream, Barbara E; Rosen, Clifford; Ammann, Patrick Bone 2011 Nov;49(5):1073-9 Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo.Zhang, Xianrong; Tamasi, Joseph; Lu, Xin; Zhu, Ji; Chen, Haiyan; Tian, Xiaoyan; Lee, Tang-Cheng; Threadgill, David W; Kream, Barbara E; Kang, Yibin; Partridge, Nicola C; Qin, Ling Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011 May;26(5):1022-34 Col3.6-HSD2 transgenic mice: a glucocorticoid loss-of-function model spanning early and late osteoblast differentiation.Yang, Maobin; Trettel, Lorin B; Adams, Douglas J; Harrison, John R; Canalis, Ernesto; Kream, Barbara E Bone 2010 Sep;47(3):573-82 New roles and mechanism of action of BMP4 in postnatal tooth cytodifferentiation.Gluhak-Heinrich, J; Guo, D; Yang, W; Harris, M A; Lichtler, A; Kream, B; Zhang, J; Feng, J Q; Smith, L C; Dechow, P; Harris, S E Bone 2010 Jun;46(6):1533-45 Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse.Gaur, Tripti; Hussain, Sadiq; Mudhasani, Rajini; Parulkar, Isha; Colby, Jennifer L; Frederick, Dana; Kream, Barbara E; van Wijnen, Andre J; Stein, Janet L; Stein, Gary S; Jones, Stephen N; Lian, Jane B Developmental biology 2010 Apr;340(1):10-21 Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: role of the calcium-calcineurin-NFAT pathway.Huang, Hechang; Chikazu, Daichi; Voznesensky, Olga S; Herschman, Harvey R; Kream, Barbara E; Drissi, Hicham; Pilbeam, Carol C Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010 Apr;25(4):819-29 PDE8 regulates rapid Teff cell adhesion and proliferation independent of ICER.Vang, Amanda G; Ben-Sasson, Shlomo Z; Dong, Hongli; Kream, Barbara; DeNinno, Michael P; Claffey, Michelle M; Housley, William; Clark, Robert B; Epstein, Paul M; Brocke, Stefan PloS one 2010 Jan;5(8):e12011 The role of proximal camp responsive element (cre) in parathyroid hormone and camp induction of human interleukin-6 promoter activityHuang Y.-F., Harrison J.R., Kream B.E. Journal of Hard Tissue Biology 2010 Jan;19(1):65-74 Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice.Gao, Qi; Zhan, Peili; Alander, Cynthia B; Kream, Barbara E; Hao, Chuanming; Breyer, Matthew D; Pilbeam, Carol C; Raisz, Lawrence G Bone 2009 Jul;45(1):98-103 Osteopenia in transgenic mice with osteoblast-targeted expression of the inducible cAMP early repressor.Chandhoke, Taranpreet K; Huang, Yu-Feng; Liu, Fei; Gronowicz, Gloria A; Adams, Douglas J; Harrison, John R; Kream, Barbara E Bone 2008 Jul;43(1):101-9 Calcitonin induces expression of the inducible cAMP early repressor in osteoclasts.Yang, Maobin; Kream, Barbara E Endocrine 2008 Jun;33(3):245-53 CREM deficiency in mice alters the response of bone to intermittent parathyroid hormone treatment.Liu, Fei; Lee, Sun-Kyeong; Adams, Douglas J; Gronowicz, Gloria A; Kream, Barbara E Bone 2007 Apr;40(4):1135-43 Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice.Notini, Amanda J; McManus, Julie F; Moore, Alison; Bouxsein, Mary; Jimenez, Mark; Chiu, W S Maria; Glatt, Vaida; Kream, Barbara E; Handelsman, David J; Morris, Howard A; Zajac, Jeffrey D; Davey, Rachel A Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007 Mar;22(3):347-56 Rearrangement of a conditional allele regardless of inheritance of a Cre recombinase transgene.Cochrane, Rebecca L; Clark, Stephen H; Harris, Adam; Kream, Barbara E Genesis (New York, N.Y. : 2000) 2007 Jan;45(1):17-20 Transgenic mice with osteoblast-targeted insulin-like growth factor-I show increased bone remodeling.Jiang, Jin; Lichtler, Alexander C; Gronowicz, Gloria A; Adams, Douglas J; Clark, Stephen H; Rosen, Clifford J; Kream, Barbara E Bone 2006 Sep;39(3):494-504 Congenic mice provide in vivo evidence for a genetic locus that modulates serum insulin-like growth factor-I and bone acquisition.Delahunty, K M; Shultz, K L; Gronowicz, G A; Koczon-Jaremko, B; Adamo, M L; Horton, L G; Lorenzo, J; Donahue, L R; Ackert-Bicknell, C; Kream, B E; Beamer, W G; Rosen, C J Endocrinology 2006 Aug;147(8):3915-23 Impaired cortical bone acquisition and osteoblast differentiation in mice with osteoblast-targeted disruption of glucocorticoid signaling.Sher, L B; Harrison, J R; Adams, D J; Kream, B E Calcified tissue international 2006 Aug;79(2):118-25 Analysis of internal deletions of a rat Col1a1 promoter fragment in transfected ROS17/2.8 cells.Ivkosic, Ante; Kronenberg, Mark S; Lichtler, Alexander C; Kream, Barbara E Collegium antropologicum 2006 Jun;30(2):401-4

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