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B.A. University of Connecticut Biology M.D. University of Connecticut Health Center Medicine

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Biomimetic Calcium Phosphate/Polyelectrolyte Multilayer Coatings for Sequential Delivery of Multiple Biological Factors.Jacobs, E; Gronowicz, G; Hurley, M; Kuhn, L T Journal of biomedical materials research. Part A 2016 Dec; FGF2 High Molecular Weight Isoforms Contribute to Osteoarthropathy in Male Mice.Burt, Patience Meo; Xiao, Liping; Dealy, Caroline; Fisher, Melanie C; Hurley, Marja M Endocrinology 2016 Oct;en20161548 FGF23 Neutralizing Antibody Ameliorates Hypophosphatemia and Impaired FGF Receptor Signaling in Kidneys of HMWFGF2 Transgenic Mice.Du, E; Xiao, L; Hurley, M M Journal of cellular physiology 2016 Jun; Loss of Bone in Sickle Cell Trait and Sickle Cell Disease Female Mice Is Associated with Reduced IGF-1 in Bone and Serum.Xiao, Liping; Andemariam, Biree; Taxel, Pam; Adams, Douglas J; Zempsky, William T; Hurley, Marja M Endocrinology 2016 May;en20152001 FGFR Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt Signaling in FGF2 High Molecular Weight Isoform Transgenic Mice.Du, Erxia; Xiao, Liping; Hurley, Marja M Journal of cellular biochemistry 2016 Jan; Age-Related Changes in FGF-2, Fibroblast Growth Factor Receptors and β-Catenin Expression in Human Mesenchyme-Derived Progenitor Cells.Hurley, Marja M; Gronowicz, Gloria; Zhu, Li; Kuhn, Liisa T; Rodner, Craig; Xiao, Liping Journal of cellular biochemistry 2015 Sep; Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2.Hurley, Marja M; Adams, Douglas J; Wang, Liping; Jiang, Xi; Meo Burt, Patience; Du, Erxia; Xiao, Liping Journal of cellular biochemistry 2015 Aug; Effects of low dose FGF-2 and BMP-2 on healing of calvarial defects in old mice.Charles, Lyndon F; Woodman, Jessica L; Ueno, Daisuke; Gronowicz, Gloria; Hurley, Marja M; Kuhn, Liisa T Experimental gerontology 2015 Apr;6462-9 Knockout of nuclear high molecular weight FGF2 isoforms in mice modulates bone and phosphate homeostasis.Homer-Bouthiette, Collin; Doetschman, Thomas; Xiao, Liping; Hurley, Marja M The Journal of biological chemistry 2014 Nov;289(52):36303-14 Optimizing BMP-2-induced bone repair with FGF-2.Gronowicz, Gloria; Hurley, Marja M; Kuhn, Liisa T The Journal of the American Academy of Orthopaedic Surgeons 2014 Oct;22(10):677-9 Fibroblast growth factor-2 isoform (low molecular weight/18 kDa) overexpression in preosteoblast cells promotes bone regeneration in critical size calvarial defects in male mice.Xiao, Liping; Ueno, Daisuke; Catros, Sylvain; Homer-Bouthiette, Collin; Charles, Lyndon; Kuhn, Liisa; Hurley, Marja M Endocrinology 2014 Jan;155(3):965-74 FGF-2 enhances Runx-2/Smads nuclear localization in BMP-2 canonical signaling in osteoblasts.Agas, Dimitrios; Sabbieti, Maria Giovanna; Marchetti, Luigi; Xiao, Liping; Hurley, Marja M Journal of cellular physiology 2013 Nov;228(11):2149-58 Fibroblast growth factor-2 and bone morphogenetic protein-2 have a synergistic stimulatory effect on bone formation in cell cultures from elderly mouse and human bone.Kuhn, Liisa T; Ou, Guomin; Charles, Lyndon; Hurley, Marja M; Rodner, Craig M; Gronowicz, Gloria The journals of gerontology. Series A, Biological sciences and medical sciences 2013 Oct;68(10):1170-80 BMP-2 differentially modulates FGF-2 isoform effects in osteoblasts from newborn transgenic mice.Sabbieti, Maria Giovanna; Agas, Dimitrios; Marchetti, Luigi; Coffin, J Douglas; Xiao, Liping; Hurley, Marja M Endocrinology 2013 Aug;154(8):2723-33 Nuclear fibroblast growth factor 2 (FGF2) isoforms inhibit bone marrow stromal cell mineralization through FGF23/FGFR/MAPK in vitro.Xiao, Liping; Esliger, Alycia; Hurley, Marja M Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Jan;28(1):35-45 Prostaglandin F2α: a bone remodeling mediator.Agas, Dimitrios; Marchetti, Luigi; Hurley, Marja M; Sabbieti, Maria Giovanna Journal of cellular physiology 2013 Jan;228(1):25-9 Fibroblast growth factor 2 stimulation of osteoblast differentiation and bone formation is mediated by modulation of the Wnt signaling pathway.Fei, Yurong; Xiao, Liping; Doetschman, Thomas; Coffin, Douglas J; Hurley, Marja M The Journal of biological chemistry 2011 Nov;286(47):40575-83 The impaired bone anabolic effect of PTH in the absence of endogenous FGF2 is partially due to reduced ATF4 expression.Fei, Yurong; Xiao, Liping; Hurley, Marja M Biochemical and biophysical research communications 2011 Aug;412(1):160-4 Fibroblast growth factor-2 stimulates the proliferation of mesenchyme-derived progenitor cells from aging mouse and human bone.Ou, Guomin; Charles, Lyndon; Matton, Seth; Rodner, Craig; Hurley, Marja; Kuhn, Liisa; Gronowicz, Gloria The journals of gerontology. Series A, Biological sciences and medical sciences 2010 Oct;65(10):1051-9 Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells.Xiao, Liping; Sobue, Takanori; Esliger, Alycia; Kronenberg, Mark S; Coffin, J Douglas; Doetschman, Thomas; Hurley, Marja M Bone 2010 Aug;47(2):360-70 Signaling pathways implicated in PGF2alpha effects on Fgf2+/+ and Fgf2-/- osteoblasts.Sabbieti, Maria Giovanna; Agas, Dimitrios; Marchetti, Luigi; Santoni, Giorgio; Amantini, Consuelo; Xiao, Liping; Menghi, Giovanna; Hurley, Marja M Journal of cellular physiology 2010 Aug;224(2):465-74 Important roles of PI3Kgamma in osteoclastogenesis and bone homeostasis.Kang, Heeseog; Chang, Woochul; Hurley, Marja; Vignery, Agnès; Wu, Dianqing Proceedings of the National Academy of Sciences of the United States of America 2010 Jul;107(29):12901-6 Nuclear isoforms of fibroblast growth factor 2 are novel inducers of hypophosphatemia via modulation of FGF23 and KLOTHO.Xiao, Liping; Naganawa, Takahiro; Lorenzo, Joseph; Carpenter, Thomas O; Coffin, J Douglas; Hurley, Marja M The Journal of biological chemistry 2010 Jan;285(4):2834-46 Fibroblast growth factor 2 positively regulates expression of activating transcription factor 4 in osteoblasts.Fei, Yurong; Xiao, Liping; Hurley, Marja M Biochemical and biophysical research communications 2010 Jan;391(1):335-9 Endogenous FGF-2 is critically important in PTH anabolic effects on bone.Sabbieti, Maria Giovanna; Agas, Dimitrios; Xiao, Liping; Marchetti, Luigi; Coffin, J Douglas; Doetschman, Thomas; Hurley, Marja M Journal of cellular physiology 2009 Apr;219(1):143-51

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