汪小龙 - 中国海洋大学 - 海洋生命学院

个人简介

教育背景 2002–2006 博士，中国海洋大学，研究方向：海洋生物技术 1996–1999 硕士，西北农林科技大学，研究方向：分子生物学 1992–1996 本科，西北农林科技大学，主修动物科学专业，辅修计算机科学专业工作经历 2006–至今中国海洋大学，副教授 2007–2008 美国俄克拉荷马州立大学（Oklahoma State University），博士后/访问学者 2001–2005 中国海洋大学，讲师 1999–2000 中国海洋大学，助教

研究领域

目前研究方向为生物技术制药、分子生物技术、生物信息学、计算生物学及其交叉学科。研究兴趣包括开发和应用新型核酸扩增技术，设计和开发新型基因转移、基因表达调控及基因治疗的方法和药物（包括反义寡核苷酸、siRNA和miRNA等）。开发新型生物计算算法，编写用户友好的生物信息学软件，用于DNA和蛋白质序列分析，数据挖掘，进行蛋白质空间结构模拟、分子系统发生、分子进化和分子生物学研究。另外，本人还对DNA计算机研究感兴趣，开发新型DNA计算算法。

近期论文

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(1). Biao Li, Shihua Dong, Jiajun Wu, Jianye Zhang, Gang Chen, Quanjiang Dong, Xinhong Zhu, Xiaolong Wang* (2013) Preparation of 5′-O-(1-Thiotriphosphate)-Modified Oligonucleotides Using Polymerase-Endonuclease Amplification Reaction (PEAR). PLoS ONE 8(7): e67558. doi:10.1371/journal.pone.0067558 (2). Shuang-yong Xu, Rebecca L. Nugent, Julie Kasamkattil, Alexey Fomenkov, Yogesh Gupta, Aneel Aggarwal, Xiaolong Wang, Zhiru Li, Yu Zheng, and Richard Morgan (2012) Characterization of Type II and III restriction-modification systems from Bacillus cereus strains ATCC10987 and ATCC14579, Journal of Bacteriology, 194(1): 49-60, doi:10.1128/JB.06248-11 (SCI IF 2010: 3.726) (3). Xiaolong WANG, Deming GOU, Shuang-yong XU. (2010) Polymerase- Endonuclease Amplification Reaction (PEAR) for Large-Scale Enzymatic Production of Antisense Oligonucleotides. PLoS ONE, 5(1): e8430. doi:10.1371/journal.pone.0008430. (SCI IF 2010: 4.351) (4). Xiaolong WANG, Zhenmin BAO, Jingjie HU, Deming GOU. (2008) DNA computing solves the 3-SAT problem with a small solution space, Current Nanoscience, 4 (4): 354-360. DOI: 10.2174/157341308786306099 (SCI IF 2008: 2.437) (5). Xiaolong WANG, Zhenmin BAO, Jingjie HU, Shi WANG, Aibin ZHAN, (2008), Solving the SAT problem using a DNA computing algorithm based on ligase chain reaction, Biosystems, 91: 117–125. doi:10.1016/j.biosystems.2007.08.006 (SCI IF 2008: 1.477) (6). Xiaolong WANG, Jingjie HU, Jie PAN, Zhuojun MA, Ke BI, Quanqi ZHANG and Zhenmin BAO. (2004), Polyethylenimine promotes sperm-mediated transgene and oligonucleotide delivery in abalone haliotis discus hannai. Journal of shellfish Research, 23(4): 1123-1127 (SCI IF 2009: 0.891) (7). Shi WANG, Lingling ZHANG , Aibin ZHAN, Xiaolong WANG, Zhanjiang Liu, Jingjie Hu and Zhenmin BAO. (2007), Patterns of concerted evolution of an rDNA family in a natural population of Zhikong scallop, Chlamys farreri. J. Molecular Evolution. 65(6): 660-667 1127 (SCI IF 2007: 3.234) (8). Aibin ZHAN, Jingjie HU, Xiaolong WANG, Wei Lu, Min Hui and Zhenmin Bao. (2006) A panel of polymorphic EST-derived microsatellite loci for the bay scallop (Argopecten irradians) J. Molluscan Studies, 72: 435-438 (SCI IF 2006: 0.968) (9). AIBIN ZHAN, ZHENMIN BAO, BING YAO, XIAOLONG WANG, MIN HUI, JINGJIE HU. (2006) Polymorphic microsatellite markers in the Zhikong scallop, Chlamys farreri, Molecular Ecology Notes, 6: 127-129 (SCI IF 2006: 1.220) (10). [Xiaolong WANG, Jie PAN，Shi WANG, et al. (2006) Identification of the Raw Material of Ejiao Using the CytB Gene PCR-RFLP Method, PERIODICAL OF OCEAN UNIVERSITY OF CHINA, 36 (4): 645-648 (Article in Chinese) ] (11). [Xiaolong WANG, Zhifa YUAN, et al. (2002) Maximum entropy principle and population genetic equilibrium, ACTA GENETICA SINICA, 29(6) 562-564 (Article in Chinese) [PDF]