近期论文
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1. Li G and Qin Y* (2018) A brief review: the mitochondrial translation factor EF4 regulated mitochondrial respiratory chain and induced the production of ROS, Free Radical Res. (accepted)
2. Zhou Z, Hu Y, Li A, Li Y, Zhao H, Wang S, Otecko NO, Zhang D, Wang J, Liu Y, Irwin DM, Qin Y & Ya-Ping Zhang* (2018) Genome wide analyses uncover allele-specific RNA editing in human and mouse，Nucleic Acids Res. https://doi.org/10.1093/nar/gky613
3. Wang F, Zhang L, Bai X, Cao X, Jiao X, Huang Y, Li Y, Qin Y* and Wen Y* (2018) (*corresponding author) Stimuli-Responsive Nanocarrier for Co-delivery of MiR-31 and Doxorubicin To Suppress High MtEF4 Cancer, ACS Applied Materials & Interfaces, doi: 10.1021/acsami.8b07698
4. Zhu P, Liu Y, Zhang F, Bai X, Chen Z, Shangguan F, Zhang B, Zhang L, Chen Q, Xie D, Lan L, Xue X, Liang X, LU B, Wei T, Qin Y* (2018) (*corresponding author) Human Elongation Factor 4 Regulates Cancer Bioenergetics by Acting as a Mitochondrial Translation Switch. Cancer research. doi: 10.1158/0008-5472.CAN-17-2059.
5. Cao X, Qin Y* (2016) (*corresponding author) Mitochondrial translation factors reflect coordination between organelles and cytoplasmic translation via mTOR signaling: Implication in disease, Free Radic Biol Med. 100, 231-7.
6. Song G, Qin Y* (2016) (*corresponding author) EF4 reveals the energy barrier for tRNA back-translocation in the peptidyl transferase center, RNA Biol. 13(10), 934-9.
7. Gao Y, Bai X, Zhang D, Han C,Yuan J, Liu W, Cao X, Chen Z, Shangguan F, Zhu Z, Gao F and Qin Y* (2016) (*corresponding author) Mammalian elongation factor 4 regulates mitochondrial translation essential for spermatogenesis, Nat Struct Mol Biol.10.1038/nsmb.3206
8. Zhang D, Kaige Y, Liu G, Song G, Luo J, Shi Y, Cheng E, Wu S, Jiang T, Lou Z, Gao N* and Qin Y* (2016) (*corresponding author) EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome, Nat Struct Mol Biol. 23, 125-131
9. Zhang Y, Mandava CS, Cao W, Li X, Zhang D, Li N, Zhang Y, Zhang X, Qin Y, Mi K, Lei J*, Sanyal S*, Gao N* (2015) (*corresponding author) HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions, Nat Struct Mol Biol. 22, 906–913.
10. Zhang D, Kaige Y, Zhang Y, Liu G, Cao X, Song G, Xie Q*, Gao N*, Qin Y* (2015) (*corresponding author) New insights into the enzymatic role of EF-G in ribosome recycling, Nucleic Acids Res. 1674–1683.
11. Liu G, Zhang D, Song G, Li Z, Zhang D, Lyv Z, Aachenbach J, Dong J, Gong W, Zhao X, Nierhaus K H and Qin Y* (2014) (*corresponding author) EF-G catalyzes tRNA translocation by disrupting interactions between decoding center and codon-anticodon duplex, Nat Struct Mol Biol. 21, 817–824.
12. Yang F, Gao Y, Li ZK, Chen LM, Xia Z, Xu T*, Qin Y* (2014) (*corresponding author) Mitochondrial EF4 links respiratory dysfunction and cytoplasmic translation in Caenorhabditis elegans. Biochim Biophys Acta. 1674–1683
13. Yamamoto H#, Qin Y#, Achenhach J#, Li X, Kijek J, Kijek J, Sphan CMT and Nierhaus HK (2014) (#co-first author) EF-G and EF4: Translocation and back-translocation on the bacterial ribosome. Nature Reviews Microbiology, 12 (2) 89-100 (Invited review).
14. Zhang D and Qin Y* (2013) (*corresponding author) The Paradox of Elongation Factor 4: highly conserved yet of no physiological significance? Biochem. J., 452 (2), 173-181 (invited review)
15. Zhang D, Liu G, Xue J, Lou J, Nierhaus K H, Gong W* and Qin Y* (2012) (*corresponding author) Common chaperone activity in the G-domain of trGTPase protects L11–L12 interaction on the ribosome, Nucleic Acids Res., 40 (21) 10851-10865.
16. Wang L, Yang F, Zhang D, Chen Z, Xu R, Nierhaus K H, Gong W and Qin Y* (2012) (*corresponding author) A conserved proline switch on the ribosome facilitates the recruitment and binding of trGTPases, Nat. Struct. Mol. Biol., 19(4)403-410
17. Di Giacco V#, Marquez V#, Qin Y#, Pech M, Triana-Alonso FJ, Wilson DN, Nierhaus KH (2008) (#co-first author). Shine-dalgarno interaction prevents incorporation of noncognate amino acids at the codon following the aug. PNAS 105(31):10715-10720.
18. Connell SR#, Topf M#, Qin Y#, Wilson DN, Mielke T, Fucini P, Nierhaus KH, Spahn CM (2008) (#co-first author) A new trna intermediate revealed on the ribosome during ef4-mediated back-translocation. Nature Struct. Mol. Biol. 15(9):910-915.
19. Qin Y, Polacek N, Vesper O, Staub E, Einfeldt E, Wilson DN, Nierhaus KH (2006) The highly conserved lepa is a ribosomal elongation factor that back-translocates the ribosome. Cell 127(4):721-733.
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