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个人简介

1980-1984 1954年毕业于北京农业大学植保系。中科院微生物所研究员,博导,中科院院士,“中科院病原微生物与免疫学重点实验室”名誉主任。武大生命科学院兼职教授及其“病毒学国家重点实验室”学术委员会名誉主任。美国病毒学会高级会员,印度病毒学会终身会员,曾任国际类病毒工作组成员。被亚太生物技术双周刊(Asia-Pacific Biotech News)遴选为亚裔著名科学家。八九届全国政协委员。五十多年来一直从事病毒学研究。承担“973”、“863”、国家十五科技攻关等以及国际合作和横向项目等。在Lancet, PNAS, Nucleic Acids Research和J. of Immunol.等国内外学术刊物上发表论文180余篇,其中70余篇为国际SCI学术刊物收录,出版编著8部。曾获中国科学院自然科学和科技进步奖五次,国家自然科学与科技进步奖两次,省部级科学与技术进步奖三次及何梁何利科学与技术进步奖等。

研究领域

研究方向:HBV T-细胞分子免疫及囊膜病毒融合机制和融合抑制剂的研究。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Pang W, Wang RR, Yang LM, Liu CM, Tien* P, Zheng* YT. Recombinant protein of heptad-repeat HR212, a stable fusion inhibitor with potent anti-HIV action in vitro. Virology, 377: 80-87, 2008. 2 Su Yan,Po Tien*, Analysis of a point mutation of H5N1 avian influenza virus hemagglutinin in relation to virus entry into live mammalian cells, Archives of Virology, 153(12): 2253-61, 2008. 3 Yan Su, Xiaodong Zhu, Yao Wang, Min Wu, Po Tien*, Evaluation of the Glu11 and Gly8 of H5N1 influenza hemagglutinin fusion peptide for membrane fusion using reverse genetics, Archives of Virology,153(2): 247-257, 2008. 4 H.G.Liu, Z.P.Fan, W.W.Chen, H.Y.Yang, Q.F.Liu, H.Zhang, P.Tien* and F.S.Wang*, A mutant HBs antigen (HBsAg) 183-191 epitope elicits specific cytotoxic T lymphocytes in acute hepatitis B patients, Clinical and Experimental Immunology, 151: 441-447, 2008. 5 Yan Su,Huaiyi Yang, Baojiang Zhang, Xiaoxuan Qi, Po Tian*, A Dual reporter gene based system to quantitate the cell fusion of avian influenza virus H5N1, Biotechonology letter,30: 73-79, 2008. 6 Lun Cai, Zheng Zhang, Lin Zhou, Haiyan Wang, Junliang Fu,Shuye Zhang, Hui Zhang, Lei Jin, Fu-Sheng Wang*,Po Tian*. 2008. Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients. Clinical Immunology, 129(3): 428-37, 2008. 7 Chang-Mei Liu, Zhuo Yang, Chao-Wu Liu, Rong Wang, Po Tien*  Roderick Dale and Lun-Quan Sun*. Myostatin antisense RNA-mediated muscle growth in normal and cancer cachexia mice. Gene Therapy. 15(3):155-60, 2008. 8 Zhuo Yang, Jingwu Zhang, Haolong Cong, Zenghong Huang, Lunquan Sun, Changmei Liu, Po Tien*, A retrovirus-based system to stably silence GDF-8 expression and enhance myogenic differentiation in human rhabdomyosarcoma cell. Journal of Gene Medicine, 10: 825–833, 2008.

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