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个人简介

学习经历: 1978–1983 中国 吉林大学 生物化学 学士学位 1984–1986 美国 纽约大学医学院 生物医学科学 硕士学位 1986–1990 美国 纽约大学医学院 生物医学科学 博士学位 工作经历: 2003年11月至今,中国科学院北京基因组研究所,研究员 2003年–2012年,中国科学院北京基因组研究所,副所长 2006年–2012年,中国科学院基因组科学与信息重点实验室,主任 1998年–2003年,中国科学院遗传研究所人类基因组中心,研究员,副主任 1993年–1998年,美国华盛顿大学(西雅图)资深研究员(Senior Fellow, non-tenure faculty position) 1990年–1993年,美国纽约大学医学院泌尿系研究助理教授

研究领域

基因组学的系统研究。包括动植物家养化、杂种优势、性别决定等基因组学机制;比较基因组学和基因组组分动力学研究(如植物、脊椎动物和节肢动物等基因组结构变化与规律);人类疾病的遗传学与基因组生物学;动植物和细菌等物种表型可塑性的分子机制; 遗传密码、分子生物学机制及细胞过程起源;DNA测序仪及测序新方法研究。

近期论文

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1. Aljohi, H. A., W. Liu, Q. Lin, J. Yu and S. Hu (2017). ISVASE: identification of sequence variant associated with splicing event using RNA-seq data. BMC Bioinformatics 18(1): 320. 2. Liu, W., C. Xin, J. Yu and H. A. Aljohi (2017). MicroRNA Expression in Multistage Date Fruit Development. Methods Mol Biol 1638: 339-351. 3. Qi, H., Y. B. Zhang, L. Sun, C. Chen, B. Xu, F. Xu, J. W. Liu, J. C. Liu, C. Chen, W. W. Jiao, C. Shen, J. Xiao, J. Q. Li, Y. J. Guo, Y. H. Wang, Q. J. Li, Q. Q. Yin, Y. J. Li, T. Wang, X. Y. Wang, M. L. Gu, J. Yu and A. D. Shen (2017). Discovery of susceptibility loci associated with tuberculosis in Han Chinese. Hum Mol Genet 26(23): 4752-4763. 4. Sui, S., Y. Yang, Y. Sun, X. M. Wang, G. L. Wang, G. L. Shan, J. C. Wang and J. Yu (2017). On the core bacterial flora of Ixodes persulcatus (Taiga tick). PLos One 12(7). 5. Xue, Y., E. W. Lameijer, K. Ye, K. L. Zhang, S. H. Chang, X. Y. Wang, J. M. Wu, G. Gao, F. Q. Zhao, J. Li, C. S. Han, S. H. Xu, J. F. Xiao, X. R. Yang, X. M. Ying, X. G. Zhang, W. H. Chen, Y. Liu, Z. Zhang, K. Huang and J. Yu (2016). Precision Medicine: What Challenges Are We Facing? Genomics Proteomics & Bioinformatics 14(5): 253-261. 6. Yuan, L., Y. Yu, Y. M. Zhu, Y. L. Li, C. Q. Li, R. J. Li, Q. Ma, G. K. H. Siu, J. Yu, T. J. Jiang, J. F. Xiao and Y. Kang (2017). GAAP: Genome-organization-framework-Assisted Assembly Pipeline for prokaryotic genomes. BMC Genomics 18. 7. Hasan Awad Aljohi, Wanfei Liu1, Qiang Lin, Yuhui Zhao, Jingyao Zeng, Ali Alamer, Ibrahim O. Alanazi, Abdullah O. Alawad, Abdullah M. Al-Sadi4 Songnian Hu, Yu J. Complete Sequence and Analysis of Coconut Palm (Cocos nucifera) Mitochondrial Genome. PLOS ONE 2016 | DOI:10.1371/journal.pone.0163990 October 13, 2016. 8. Tang CR, Yang M, Fang YJ, Luo YF, Gao SH, …, Yu J, Hu SN and Huang HS. (2016) The rubber tree genome reveals new insights into rubber production and species adaptation. Nature Plants 16073 (2016) doi:10.1038/nplants.2016.73 9. Xin S, Wu JY, Sun QQ, Li X, Xian F, Sun M, Fang W, Chen ML, Yu J, Xiao JF. (2016) MTD: a mammalian transcriptomic database to explore gene expression and regulation. Briefings in Bioinformatics 2016 Jan 27. pii: bbv117. [Epub ahead of print] 10. Zhang YB, J Hu, J Zhang, X Zhou, X Li, C Gu, T Liu, Y Xie, Dr. J Liu , M Gu , P Wang, T Wu, J Qian , Y Wang , J Yu , Q Zhang. (2015) Genome-wide Association Study Identifies Multiple Susceptibility Loci for Craniofacial Microsomia. Nature Communications 7:10605. doi: 10.10 7:10605. doi: 10.1038/ncomms10605. 38/ncomms10605. 11. Meili Chen, Yibo Hu, Jingxing Liu, Qi Wu, Chenglin Zhang, Jun Yu, Jingfa Xiao, Fuwen Wei & Jiayan Wu. (2015) Improvement of genome assembly completeness and identification of novel full-length protein-coding genes by RNA-seq in the giant panda genome. Sci Reports 5: 18019 (2015). 12. Gu ZQ, Wang BB, Zhang YB, Ding H, Zhang YL, Yu J, Gu ML, Chan P, Cai YN. (2015) Association of ARNTL and PER1 genes with Parkinson's disease: a case-control study of Han Chinese. Sci Reports 5: 15891. 13. Chen F, Li Q, Gu M, Li X, Yu J, Zhang YB. (2015) Identification of a Mutation in FGF23 Involved in Mandibular Prognathism. Sci Reports 2015 5:11250. 14. Sun LY, Zhang YB, Jiang L, Wan N, Wu WF, Pan XD, Yu J, Zhang F, Wang L. Identification of the gene defect responsible for severe hypercholesterolaemia using whole-exome sequencing. Sci Reports 5:11380. 15. Yu J. (2015). The Human Transcriptomes Project: Is it hard? Next Generat Sequenc & Applic 2:2. 16. Wang D, Xu JY, Yu J. (2015) KGCAK: a K-mer based database for genome-wide phylogeny and complexity evaluation. Biology Direct 10:53. 17. Wang D, Yu J ?. (2015) LCGserver: A Webserver for Exploring Evolutionary Trajectory of Gene Orders in a Large Number of Genomes. OMICS 19:574–577. 18. Chengqi Xin, Wanfei Liu, Qiang Lin, Xiaowei Zhang, Peng Cui, Fusen Li, Guangyu Zhang, Linlin Pan, Ali Al-Amer, Hailiang Mei, Ibrahim S. Al-Mssallem, Songnian Hu, Hasan Awad Al-Johi, Jun Yu?. (2015) Profiling MicroRNA Expression during Multi-staged Date Palm (Phoenix dactylifera L.) Fruit Development. Genomics 105:242–251. 19. Yongbing Zhao, Jinlong Yin, Haiyan Guo, Yuyu Zhang, Wen Xiao, Chen Sun, Jiayan Wu, Xiaobo Qu, Jun Yu, Xumin Wang, and Jingfa Xiao. (2015) The complete chloroplast genome provides insight into the evolution and polymorphism of Panax ginseng. Front Plant Sci 5: 696.

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